A5054036135- Retinal Diseases and Treatments
- Retinal Imaging and Analysis
- Global Cancer Incidence and Screening
- Antioxidant Activity and Oxidative Stress
- Effects of Radiation Exposure
- Cancer Risks and Factors
- Radiation Dose and Imaging
- Colorectal Cancer Screening and Detection
- Tuberculosis Research and Epidemiology
- Menopause: Health Impacts and Treatments
- Radioactive contamination and transfer
- Retinal and Optic Conditions
- Estrogen and related hormone effects
- Glaucoma and retinal disorders
- Global Public Health Policies and Epidemiology
- Birth, Development, and Health
- Nutritional Studies and Diet
- Ethics in Clinical Research
- Pneumonia and Respiratory Infections
- Ophthalmology and Visual Impairment Studies
- Acute Myocardial Infarction Research
- Fatty Acid Research and Health
- melanin and skin pigmentation
- Global Health Care Issues
- Insurance, Mortality, Demography, Risk Management
National Institute for Health Development
2010-2023
University College London
2012
National Eye Institute
2012
University of Cambridge
2012
Netherlands Institute for Neuroscience
2012
London School of Hygiene & Tropical Medicine
2012
National Institutes of Health
2006-2011
Danish Cancer Society
2011
Tampere University
2003-2011
Finnish Cancer Registry
2011
Age-related macular degeneration (AMD) is the most common cause of incurable visual impairment in high-income countries. Previous studies report inconsistent associations between AMD and apolipoprotein E (APOE), a lipid transport protein involved low-density cholesterol modulation. Potential interaction APOE sex, smoking status has been reported. We present pooled analysis (n = 21,160) demonstrating late APOε4 (odds ratio [OR] 0.72 per haplotype; confidence interval [CI]: 0.65-0.74; P...
Myopia is becoming increasingly common globally and associated with potentially sight-threatening complications. Spending time outdoors protective, but the mechanism underlying this association poorly understood.To examine of myopia ultraviolet B radiation (UVB; directly sunlight exposure), serum vitamin D concentrations, pathway genetic variants, adjusting for years in education.A cross-sectional, population-based random sample participants 65 older was chosen from 6 study centers European...
Purpose: To determine the prevalence of visual impairment (VI) in populations 65 year or older from six European countries and describe association with vision-related quality life. VI was defined according to WHO as best corrected acuity <6/18/log MAR >0,48 (World Health Organization (1992): International Statistical Classification Diseases Related Problems, 10th revised ed. Vol 1. Geneva). Methods: 4166 participants The Eye study, years selected randomly general census participating...
Abstract Aim To evaluate the association between hyperglycaemia on admission, previously known diabetes and 180‐day mortality in acute myocardial infarction (AMI) patients. Methods The study population consisted of 779 consecutive AMI patients from Myocardial Infarction Registry Estonia who had an admission venous plasma glucose level recorded were admitted to Tartu University Clinics within a period 2 years. Logistic regression analysis was used estimate crude adjusted odds ratios (OR) with...
<h3>Objective:</h3> To examine the association between self-reported diabetes history and early or late age-related macular degeneration (AMD) in European population. <h3>Methods:</h3> Participants aged 65 years over cross-sectional population-based EUREYE study underwent an eye examination including digital retinal photography. The images were graded at a single centre. A structured questionnaire was administered by trained field workers for putative risk factors AMD of mellitus. Logistic...
The aims of the EUREYE study are to evaluate prevalence age-related maculopathy (ARM), including macular degeneration (AMD), in elderly European populations, investigate risk factors for ARM and AMD, especially solar radiation diet, measure impact these conditions on vision-related quality life.A population-based cross-sectional with retrospective current exposure measurements. Risk factor assessment is via questionnaires (for lifestyle such as smoking alcohol, dietary factors, outdoor...
Success of genetic association and the prediction phenotypic traits from DNA are known to depend on accuracy phenotype characterization, amongst other parameters. To overcome limitations in characterization human iris pigmentation, we introduce a fully automated approach that specifies areal proportions proposed represent differing pigmentation types, such as pheomelanin, eumelanin, non-pigmented areas within iris. We demonstrate utility this using high-resolution digital eye imagery...
Two cohorts of Chernobyl cleanup workers from Estonia (4,786 men) and Latvia (5,546 were followed 1986 to 1998 investigate cancer incidence among persons exposed ionizing radiation the accident. Each cohort was identified various independent sources using nationwide population mortality registries. Cancers ascertained by linkage with Overall, 75 incident cancers in Estonian 80 Latvian cohort. The combined-cohort standardized ratio (SIR) for all 1.15 (95% confidence interval (CI) = 0.98-1.34)...
Background: The determinants of teenage sexual health, including pregnancies, can be addressed from social, familial and individual level perspectives. main objective this study was to examine whether pregnancy among 18 years old younger girls were associated with selected (age at coitarche, score health knowledge, dislike school) family (mother's education) functioning (alcohol abuse in the family, parents' acceptance relationship) characteristics. Methods: An interview survey two medical...