Jan Ševčı́k

ORCID: 0000-0001-7174-593X
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About
Contact & Profiles
Research Areas
  • Diptera species taxonomy and behavior
  • Insect behavior and control techniques
  • Fossil Insects in Amber
  • Hymenoptera taxonomy and phylogeny
  • Education, Psychology, and Social Research
  • Forensic Entomology and Diptera Studies
  • Neuropeptides and Animal Physiology
  • Plant and animal studies
  • CRISPR and Genetic Engineering
  • BRCA gene mutations in cancer
  • Entomopathogenic Microorganisms in Pest Control
  • Forest Insect Ecology and Management
  • RNA Research and Splicing
  • RNA and protein synthesis mechanisms
  • DNA Repair Mechanisms
  • Pain Mechanisms and Treatments
  • Forest Ecology and Biodiversity Studies
  • Molecular Biology Techniques and Applications
  • Neuroscience and Neuropharmacology Research
  • Cancer Genomics and Diagnostics
  • Viral Infections and Vectors
  • Receptor Mechanisms and Signaling
  • Research on Leishmaniasis Studies
  • Trypanosoma species research and implications
  • Coleoptera Taxonomy and Distribution

University of Ostrava
2016-2025

Silesian Museum
2012-2024

Charles University
2012-2023

Vitalant
2023

Brno University of Technology
2018-2020

Bayer (Germany)
2019

Ludwig-Maximilians-Universität München
2019

The University of Queensland
2018-2019

Environmental Technologies (United States)
2017

University of New York in Prague
2016

The genus Pseudoaerumnosa Rudzinski, 2006 is redefined. includes the following species which are described, illustrated and keyed: acinacea sp. n., P. ampliata annae awanensis banari clavidactyla clivicola collicola consuota cryptoloba curvifalx eminula exacuta filispicata formosa fragilis impensa inviolata 2006, junciseta obovata pilicaudata quadriquetra saginata tenuidens n. tkoci Morphological characters phylogenetic position of discussed. For some species, barcode (COI) sequence data...

10.11646/zootaxa.4656.1.1 article EN Zootaxa 2019-08-13

Four Oriental species of Aerumnosa Mohrig, 1999 (Diptera: Sciaridae), a genus previously known only from Papua New Guinea, are newly described and illustrated: bituberculata sp. n. (India), A. gemmifera (Malaysia: Sabah), horrifica (Brunei, Thailand) impar Sabah). On the basis new material, is redefined. A key to presented, including four species. An updated molecular phylogenetic analysis based on gene markers (18S, 28S, 16S COI) shows be member subfamily Cratyninae. The monophyly...

10.11646/zootaxa.4399.2.8 article EN Zootaxa 2018-03-21

Germline mutations in checkpoint kinase 2 ( CHEK2 ), a multiple cancer‐predisposing gene, increase breast cancer (BC) risk; however, risk estimates differ substantially published studies. We analyzed germline variants 1,928 high‐risk Czech breast/ovarian (BC/OC) patients and 3,360 population‐matched controls (PMCs). For functional classification of VUS, we developed complementation assay human nontransformed RPE1‐ ‐knockout cells quantifying CHK2‐specific phosphorylation endogenous protein...

10.1002/ijc.32385 article EN International Journal of Cancer 2019-05-03

A new phylogenetic hypothesis is proposed for the relationships among species within genus Docosia Winnertz, 1863, based on a combined analysis of five DNA markers (28S, ITS2, COI, COII and CytB). Five are described, anatolica Ševčík sp. nov. from Turkey, D. japonica Kurina Japan, peloponnensis Greece, svanetica Caucasus polyspina Russian Far East. New country records following presented: diutina Plassmann, 1996 (Turkey), flavicoxa Strobl, 1900 (Georgia), gilvipes (Haliday in Walker, 1856)...

10.5852/ejt.2020.717.1095 article EN cc-by European Journal of Taxonomy 2020-09-17

The phylogeny of the insect infraorder Bibionomorpha (Diptera) is reconstructed based on combined analysis three nuclear (18S, 28S, CAD) and mitochondrial (12S, 16S, COI) gene markers. All analyses strongly support monophyly in both narrow ( sensu stricto ) broader lato concepts. major lineages (Sciaroidea, Bibionoidea, Anisopodoidea, Scatopsoidea) most included families are supported as monophyletic groups. Axymyiidae was not found to be part nor it its sister group. Bibionidae paraphyletic...

10.7717/peerj.2563 article EN cc-by PeerJ 2016-10-18

The genus Cabamofa, previously containing only C. mira from Costa Rica (Jaschhof 2005), is shown here to have a second species in Thailand, which described and named orientalis sp. nov. new known single male collected by the TIGER Project (Thailand Inventory Group for Entomological Research), mass-sampling program inventory insect diversity Southeast Asia (Plant et al. 2011; http://sharkeylab.org/tiger, accessed 14 December 2018). As circumstances of finding indicate, decidedly rare species,...

10.11646/zootaxa.4576.2.12 article EN Zootaxa 2019-04-02

We describe the earliest known representatives of subfamily Hesperininae, and species extant genus Penthetria, from mid-Cretaceous amber Myanmar. Penthetria is represented by tenue sp. nov. tipuloides also seven new in recently described Protopenthetria Li et al, 2021, which we provisionally place Hesperininae. In nominate subgenus (s.str.) rectangula P. longicornis are probably related to skartveiti al., 2021. The Megacephaletria subgen.n. described, including five species,...

10.11646/zootaxa.5601.3.3 article EN Zootaxa 2025-03-09

Abstract Ambrosia gall midges (AGM) represent an intriguing group within the Cecidomyiidae, one of most diversified dipteran families. AGM form galls on plants, where they cultivate and consume fungal symbionts (phytomycetophagy). This mutualistic relationship may play a critical role in larval nutrition, morphogenesis, protection against natural enemies. Although other fungus-farming taxa have been intensively studied, largely neglected. review synthesises current knowledge diversity,...

10.1093/femsre/fuaf010 article EN FEMS Microbiology Reviews 2025-04-02

Alterations in dihydropyrimidine dehydrogenase gene (DPYD) coding for the key enzyme (DPD) of fluoropyrimidines (FPs) catabolism contribute to development serious FPs-related toxicity. We performed mutation analysis DPYD based on cDNA sequencing 76 predominantly colorectal cancer patients treated by FPs with early high (grade 3-4) hematological and/or gastrointestinal Six previously described [85T>C (C29R), 496A>G (M166V), 775A>G (K259E), 1601G>A (S534N), 1627A>G (I543V), IVS14+1G>A, 2194G>A...

10.4149/neo_2009_04_303 article EN Neoplasma 2009-01-01

In this study, we surveyed six species of cockroaches, two synanthropic (i.e. ecologically associated with humans) and four wild, for intestinal trypanosomatid infections. Only the wild cockroach were found to be infected, flagellates genus Herpetomonas. Two distinct genotypes documented, one which was described as a new species, Herpetomonas tarakana sp. n. We also propose revision creation subfamily, Phytomonadinae, include Herpetomonas, Phytomonas, newly Lafontella gen. (type mariadeanei...

10.1111/jeu.12268 article EN Journal of Eukaryotic Microbiology 2015-09-09

Fungivorous gall midges of the subfamilies Lestremiinae, Micromyinae, Winnertziinae and Porricondylinae were largely neglected in previous inventories Diptera faunas Czech Slovak Republics. A taxonomic-faunistic study focusing on these identified a total 80 species, which 49 are new records for Republic 33 Slovakia. Species that have never before been found central Europe Aprionus dalarnensis Mamaev, 1998, A. oligodactylus Jaschhof, 2009, pigmentalis Asynapta inflata Spungis, 1988,...

10.5852/ejt.2017.303 article EN cc-by European Journal of Taxonomy 2017-03-22

1. Intracellular recordings were made in a pontine slice preparation of the rat brain containing nucleus locus coeruleus (LC). Locus neurons responded to brief hypoxic stimuli (replacement 95% O2‐5% CO2 with N2‐5% CO2) hyperpolarization and cessation spontaneous action potentials. When cells continuously hyperpolarized by about 15 mV order abolish firing, hypoxia induced an early depolarization (HD), followed (HH) after reoxygenation, posthypoxic (PHH). These responses accompanied decrease...

10.1113/jphysiol.1995.sp020788 article EN The Journal of Physiology 1995-07-01

Tramadol is a centrally acting analgesic with low opioid receptor affinity and, therefore, presumably additional mechanisms of action. and its main metabolite O‐desmethyltramadol were tested on rat central noradrenergic neurones the nucleus locus coeruleus (LC), which are involved in modulation nociceptive afferent stimuli. In pontine slices brain spontaneous discharge action potentials LC cells was recorded extracellularly. (−)‐Tramadol (0.1–100μ m ), (+)‐tramadol (0.1–100 μ...

10.1111/j.1476-5381.1993.tb13788.x article EN British Journal of Pharmacology 1993-09-01

Abstract The phylogeny of the fungus gnat family Mycetophilidae (Diptera) is reconstructed with a focus on species‐rich and taxonomically difficult subfamilies Gnoristinae Mycomyinae. multigene phylogenetic analyses are based five nuclear (18S, 28S, CAD, MCS, ITS2) four mitochondrial (12S, 16S, COI, CytB) gene markers. strongly support monophyly Manotinae, Sciophilinae, Leiinae, Mycomyinae, although paraphyletic respect to Mycetophilinae. All genera groups included supported as monophyletic,...

10.1111/syen.12312 article EN Systematic Entomology 2018-07-10

The phylogeny of Cecidomyiidae (Diptera) is reconstructed based on the combined analysis nine genetic markers (18S, 28S, EF1α, CAD1, CAD2, CAD5, 12S, 16S and COI). resulting hypotheses are compared contrasted with morphology-based classification prevailing for family. monophyly well supported, as subfamilies Lestremiinae, Catotrichinae Cecidomyiinae. Molecular shows Lestremiinae to be earliest branching lineage, which in conflict generally accepted idea having most generalized morphology...

10.1093/zoolinnean/zly029 article EN Zoological Journal of the Linnean Society 2018-04-13

We provide the first molecular phylogeny of Keroplatidae and Lygistorrhinidae, families fungus gnats (Diptera: Bibionomorpha: Sciaroidea). Phylogenies reconstructed by Maximum Likelihood Bayesian methods, based on four nuclear mitochondrial gene markers (5106 base pairs) sequenced for 75 genera 105 species, show as monophyletic only with family Lygistorrhinidae included, herewith treated subfamily Lygistorrhininae stat. nov. The Arachnocampinae is retained in family, although lowering its...

10.3390/insects11060348 article EN cc-by Insects 2020-06-04
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