A5045047427- Diabetes Treatment and Management
- Pituitary Gland Disorders and Treatments
- Adrenal Hormones and Disorders
- Sexual Differentiation and Disorders
- Genetic Syndromes and Imprinting
- Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
- Metabolism, Diabetes, and Cancer
- Growth Hormone and Insulin-like Growth Factors
- Hormonal Regulation and Hypertension
- Medical Imaging and Pathology Studies
- Diabetes Management and Research
- Adrenal and Paraganglionic Tumors
- Pancreatic function and diabetes
- Dermatological and Skeletal Disorders
- Vitamin D Research Studies
- Hormonal and reproductive studies
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Liver Disease Diagnosis and Treatment
- Pregnancy and preeclampsia studies
- Ion channel regulation and function
- Thyroid Disorders and Treatments
- Gestational Diabetes Research and Management
- Parathyroid Disorders and Treatments
- Thyroid Cancer Diagnosis and Treatment
- Hyperglycemia and glycemic control in critically ill and hospitalized patients
Institute of Post Graduate Medical Education and Research
2008-2024
Nil Ratan Sircar Medical College and Hospital
2013-2022
Medical College and Hospital, Kolkata
2008-2022
Pandit Bhagwat Dayal Sharma Post Graduate Institute of Medical Sciences
2020
The association of anemia with primary hypothyroidism has been common knowledge for many years. However; its pathogenesis is far from clear in cases. Often the causes are manifold.In this study, we evaluated patients hypothyroidism.Sixty adult nonpregnant untreated hypothyroid without any obvious cause were included. All subjected to full medical history, clinical examination, biochemical and imaging studies. Serum iron profile, vitamin B12, folic acid, anti parietal cell antibody, TPO bone...
Summary A 17-year-old girl presented with recurrent attacks of acute pancreatitis, associated severe hyperglycemia and hypertriglyceridemia, despite being on intensive insulin therapy for the last 10 years. She had acanthosis nigricans, generalized loss subcutaneous fat prominent veins over extremities. The serum levels glucose triglyceride did not reduce significantly, even maximally tolerated doses metformin (2 g), pioglitazone (45 mg) fenofibrate (160 mg), uncommonly seen in poor rural...
<b>Objective:</b> To compare the effectiveness and safety of add on therapy bromocriptine with metformin in type 2 diabetes mellitus (DM) patients.<br> <b>Material Methods:</b> Adult DM patients fulfilling inclusion criteria were randomized three groups. Group A received (1000 mg/ day), while group B treated mg/day) plus (0.8 C (1.6 for 12 weeks. Fasting plasma glucose (FPG), postprandial (PPPG), body weight measured at week 4, 8, visits glycosylated hemoglobin (HbA <sub>1C</sub> ) visit....
Hypothyroidism presenting as recurrent hypokalemic paralysis is rare in the literature. This transient and episodic neurological condition commonly associated with thyrotoxicosis. We report a case of young female admitted paralytic attacks since last 1 year. She had no symptom hypothyroidism. weakness all four limbs, delayed relaxation ankle jerks, normal higher mental function. There was enlargement thyroid. Serum potassium level ranged from 1.6 to 3.2 meq/L during attack high serum...
Diabetic dyslipidaemia poses a therapeutic challenge. New therapies have emerged in this patient subgroup to enhance outcome and improve compliance.The aim of study was compare the effectiveness safety add on therapy saroglitazar fenofibrate with metformin Indian patients diabetic dyslipidaemia.Adults fulfilling inclusion criteria were randomized two groups. Group A received (1000 mg/ day) (160 mg/day) while group B (4 mg/day). Glycosylated haemoglobin (HbA1C), triglyceride (TG), LDL-...
Here we report a case of young male who developed full blown iatrogenic Cushing's syndrome after use superpotent clobetasol propionate cream 0.05% for long duration to suppress psoriatic skin lesions. He also osteoporosis and hypogonadism. This demonstrates that injudicious topical steroids can have disastrous consequences.
BACKGROUNDMetformin has established as an ideal first-line treatment for type 2 diabetes and hypothetically a particularly attractive drug use in pregnancy.Metformin is known to cross the placenta its pregnancy been limited by concerns regarding potential adverse effects on both mother foetus.Randomised trials assess efficacy safety of Gestational Diabetes Mellitus (GDM) are lacking. METHODSSeventy six women with singleton diagnosed GDM per International Association Pregnancy Study Groups...
Background: Neonatal sepsis is a frequent and important cause of morbidity mortality which accounts for one quarter neonatal deaths. There are very few studies done in India to evaluate the role MPV as diagnostic marker sepsis.Methods: Prospective case control study tertiary care hospital. Neonates > 30 weeks gestation admitted intensive unit during period 1 year with clinically suspected were included study. Septic screen positive culture group A normal neonates Group B. was all subjects...
Klinefelter syndrome usually presents in the puberty and adulthood with its characteristic features. We report a boy who had hypospadias hydrocele.Six half year old complaints of genitourinary problem form hypospadias, small phallus hydrocele. Karyotyping showed 47,XXY.This case illustrates that was presented infancy hydrocele which are very uncommon presentation disease.
A 6½ years Indian boy was brought by his parents, who were anxious about the excessive increase in size of boy's phallus, from age 2 years. On physical examination, child had a penis length greater than 97th centile for age, sexual maturity rating gonads at stage and pubic hair 3, with height high normal range (90–97th centile). The bone 12 Laboratory evaluation showed pubertal levels testosterone gonadotropin response to stimulation, confirming central precocious puberty (CPP)....
46, XY difference/disorder of sex development (DSD) is a relatively uncommon group heterogeneous disorders with varying degree underandrogenization male genitalia. Such patients should be approached systematically to reach an aetiological diagnosis. However, we lack, at present, clinical practice guideline on diagnostic approach in DSD from this part the globe. Moreover, debate persists regarding timing and cut-offs different hormonal tests, performed these cases. The consensus committee...
This 7-year-old female, born out of non-consanguineous marriage, normal vaginal delivery, first in birth order without any history prolonged perinatal complications presented with short stature, progressive enlargement breasts, and galactorrhoea. Developmental milestones were achieved as per age, but her scholastic performance is below average. Menarche was attained at 5 years. Despite pubertal precocity, she had no pubic or axillary hair. On examination, height 112 cm (less than third...
A 23-year-old female presented with headache, palpitation, and hypertensive spells. There was no similar family history. Twenty-four (24) hour urine testing showed elevated normetanephrine level normal metanephrines [metanephrines 123 mcg/24 hrs (74-297); normetanephrines 5321.16 (73-808)]. biochemical diagnosis of normetanephrine-secreting pheochromocytoma made. Considering the age reports, a functional scan ordered. Imaging 18-FDG PET CT done which uptake indicative large left adrenal...
Rickets, one of the leading causes bony deformities and short stature, can be calciopenic (inciting event is defective intestinal calcium absorption) or phosphopenic phosphaturia). Early diagnosis timely treatment rickets are crucial for correction limb deformities. Guidelines exist nutritional rickets, but management relatively uncommon forms complex. This consensus aims to formulate a simplified diagnostic approach especially in resource-limited settings. The statement has been formulated...
The association between long-term metformin use in type 2 diabetes mellitus (T2DM) and low vitamin B12 levels has been proven screening for the same is recommended by American Diabetes Association (ADA) guidelines. potential of deficiency to cause or worsen diabetic peripheral neuropathy (DPN) T2DM patients investigated previous studies. However, prevalence estimates treated with long term having established DPN lacking our country. aim study was estimate on find out risk factors these patients.
Introduction: We report an unusual case of normotensive pheochromocytoma detected incidentally, presenting a pre-operative management problem. Case Note: A 40-year-old lady with vague abdominal symptoms was initially discovered left adrenal incidentaloma by ultrasound abdomen, which also revealed in computed tomography (CT). After exclusion all the causes possible necessary investigations, confirmed elevated 24 hour urinary metanephrine and normetanephrine. Her blood pressure low to range...
Background: Type 2 diabetes mellitus (DM) is mainly due to multifactorial of which insulin resistance and deficiency in the incretion are two important pathophysiological factors. Vildagliptin, an oral hypoglycemic agent, acts by inhibiting dipeptidyl peptidase-4 enzyme, often uses as a first line drug along with metformin enhance outcome. Aim Objective: The aim this study was compare effectiveness safety vildagliptin 50 mg twice daily dose 100 sustained release tablet (SR) once DM patients...
Vitamin D deficiency is widespread globally and associated with type 2 diabetes mellitus (T2DM). Studies suggest markedly lower prevalence of vitamin in outdoor workers compared to indoor workers. However, data on the status T2DM lacking.We assessed residing across several districts Southern West Bengal, India.The present study a descriptive observational study.A total 128 were for serum 25-hydroxyvitamin (25(OH)D) during December 2019 after excluding common confounders except sun exposure...
Mauriac syndrome (MS) is one of the rare complications poorly controlled Type 1 Diabetes Mellitus (T1DM). It characterized by poor glycemic control, short stature hepatomegaly, Cushingoid features and delayed puberty [1]. Since introduction easy availability longer acting insulin analogues, cases are hardly reported now [2]. This more frequently encountered in children adolescents with control increases susceptibility micro vascular like diabetic retinopathy nephropathy. most common cause...