A5010794266- Pituitary Gland Disorders and Treatments
- Sexual Differentiation and Disorders
- Adrenal and Paraganglionic Tumors
- Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
- Diabetes Management and Research
- Diabetes and associated disorders
- Metabolism, Diabetes, and Cancer
- Growth Hormone and Insulin-like Growth Factors
- Pancreatic function and diabetes
- Hormonal Regulation and Hypertension
- Hormonal and reproductive studies
- Infectious Diseases and Tuberculosis
- Diagnosis and treatment of tuberculosis
- Nuclear Structure and Function
- Skin Diseases and Diabetes
- Diabetes Treatment and Management
- Parathyroid Disorders and Treatments
- Hyperglycemia and glycemic control in critically ill and hospitalized patients
- Neuroendocrine Tumor Research Advances
- Diabetic Foot Ulcer Assessment and Management
- Systemic Lupus Erythematosus Research
- Hypothalamic control of reproductive hormones
- Connective tissue disorders research
- Bone health and treatments
- Genetic Syndromes and Imprinting
KPC Medical College and Hospital
2006-2025
Medical College and Hospital, Kolkata
2012-2024
Institute of Post Graduate Medical Education and Research
2013-2023
Midnapore Medical College and Hospital
2010-2022
Creative Commons
2021
Indian Institute of Science Education and Research Pune
2020
University of Ottawa
2020
Yahoo (United Kingdom)
2016-2019
Google (United States)
2018
Bose Institute
2015
Abstract Morbidity and mortality rates in patients with autosomal recessive, congenital generalized lipodystrophy type 4 (CGL4), an ultra‐rare disorder, remain unclear. We report on 30 females 16 males from 10 countries biallelic null variants CAVIN1 gene (mean age, 12 years; range, 2 months to 41 years). Hypertriglyceridemia was seen 79% (34/43), hepatic steatosis 82% (27/33) but diabetes mellitus only 21% (8/44). Myopathy elevated serum creatine kinase levels (346–3325 IU/L) affected all...
Abstract Introduction: Cortisol concentration is often estimated by competitive chemiluminescent immunoassays, which are prone to interference due cross-reactivity. The extent of inconsistent across different adrenal disorders and among analyzers. Although liquid chromatography-mass spectrometry (LC-MS/MS) possesses better analytical specificity, it not widely available. We aimed compare cortisol values measured four analyzers disorders. Methods: concentrations were in the serum patients...
Dispersal syndromes (i.e. suites of phenotypic correlates dispersal) are potentially important determinants local adaptation in populations. Species that exhibit sexual dimorphism their life history or behaviour may sex-specific differences dispersal syndromes. Unfortunately, there is little empirical evidence sex and how they respond to environmental change evolution. We investigated these issues using two same-generation studies a long-term (greater than 70 generations) selection...
Background: Off-loading of the ulcer area is extremely important for healing plantar ulcers. with total contact cast (TCC) may be superior to other off-loading strategies studied so far, but practical limitations can dissuade clinicians from using this modality. This study was conducted evaluate efficacy TCC compared that a pressure-relieving ankle foot orthosis (PRAFO) in diabetic neuropathic ulcers and their effect on gait parameters. Methods: Thirty adult patients attending clinic...
Hemichorea-hemiballism (HCHB) is a hyperkinetic disorder characterized by continuous, nonpatterned, proximal, involuntary movements on one side of the body, resulting from involvement contralateral basal ganglia and particularly striatum. We report here an interesting case sudden onset HCHB associated with nonketotic hyperglycemia, complete remission symptoms after control blood glucose. as first presentation type 2 diabetes has been described rarely. This reinforces that, especially in...
Background: Traditionally, enteric feeds are withheld for a period of 48-72 hrs, sometimes even more following anastomosis depending upon return full peristaltic sounds. This results in nonstimulation gut Gut Rest, which was supposed to result better anastomotic healing. But this same also deprives the intestinal mucosa surface nutrients as well prolongs parenteral fluid therapy, thereby depriving patients adequate nutrition. Along with it, prolonged therapy keeps bound bed its resultant...
Abstract Introduction: We aimed to describe the clinical, biochemical and etiological profile of patients referred with a provisional diagnosis rickets in tertiary care centres. In addition, we tried propose diagnostic algorithm for evaluation such patients. Methods: This was retrospective cross-sectional study conducted two centres West Bengal. Data were retrieved between 2014 2021. Results: Out 101 children, 22 had conditions simulating rickets. Renal tubular acidosis (RTA) most common...
ABSTRACT While hypoglycemia is a frequent problem encountered in clinical practice, endogenous hyperinsulinemic patient with diabetes rare. Here, we describe such case of recurrent due to multifocal insulinoma (differential focal nesidioblastosis) an adult diabetes. The diagnostic dilemma, pitfalls interpreting advanced imaging techniques, and difficulty management underlying have been focused. utility acarbose uncooked cornstarch maintain euglycemia while combating two opposite sinister...
Though the pancreas has traditionally been considered a combination of two separate organ systems, both exocrine and endocrine portions are structurally functionally interrelated. Disease processes diffusely involving can give rise to dysfunctions pancreatic diseases account for less than 0.5% all cases diabetes. Chronic pancreatitis fibrocalculous diabetes most common which beta cell dysfunction On contrary, prominent changes in structure functions have identified significant number...
A 19-year-old male patient presented with a year-long history of progressive painful enlargement his hands and feet associated excessive sweating greasiness the face, palms soles. He also noticed pain over wrists ankles without any symptoms suggestive raised intracranial tension no recent increase in height. Family was unremarkable. Clinical examination revealed digital clubbing spade-like appearance (figures 1 2). The eyelids were hypertrophied partial drooping upper eyelids. skin patient's...
A 40-year-old woman presented after 3 years of progressively increasing proximal muscle weakness, severe myalgia and generalised bone pain. Clinical examination revealed weakness (power grade 3/5), diffuse bony tenderness kyphoscoliosis. Baseline biochemistry low serum phosphate (1.5 mg/dL) elevated alkaline phosphatase (552 IU/L (reference: 98–251 IU/L)) with normal calcium (corrected 9.2 mg/dL), creatinine (0.5 mg/dL), 25-hydroxy-vitamin D (34 ng/mL), calcitriol (32 pg/mL 19.6–54.3 pg/mL))...
A 16-year-old boy presented with complaints of recent onset difficulty in walking, progressive diminution vision and a long-standing persistent occipital headache. Physical examination suggested cerebellar ataxia, positive signs, macrocephaly bilateral papilloedema. MRI the brain revealed mass lesion prominent striated folial pattern involving right hemisphere causing obstructive hydrocephalus. The appeared hypointense on T1 (figure 1) hyperintense T2 2) weighted images, parallel linear...
Insulin hypersensitivity—a rare occurrence with currently available insulin preparations—may have varied manifestations, ranging from a local injection site allergy to severe generalized anaphylactic reactions. While various additives included in commercial preparations and peptides themselves remain the primary allergens responsible, faulty technique may at times potentiate development of allergy. Management is complex, potentially dangerous times, can be challenging for treating physician....
Pseudoacromegaly, or acromegaloidism, is characterised by a clinical appearance mimicking acromegaly in the absence of documented hypersomatotropism past exposure to excess growth hormone. It can develop secondary number congenital and acquired conditions which severe insulin resistance an important example. Lipodystrophy syndromes are group rare disorders autosomal recessive generalised lipodystrophy most common type. Patients with this disorder predisposed its associated complications such...
A 52-year-old man presented with high-grade fever, headache and painful vesicular skin rash involving the upper trunk extremities, 8 days after initiation of chemotherapy azathioprine (50 mg/day), which had been prescribed for acral vitiligo. There was neither any history preceding respiratory or gastrointestinal tract infection, nor patient known to have malignancy, drug hypersensitivity, inflammatory bowel disease, vasculitis other autoimmune disease. Laboratory results revealed...
A 65-year-old non-obese (body mass index 22.8 kg/m2) man with a long history of type 2 diabetes noticed unilateral, dull aching pain over the left side his upper abdomen for 3 months and subsequent swelling overlying area (figure 1), which prompted him to seek surgical consultation. working diagnosis lumbar hernia uncontrolled (fasting, postprandial plasma glucose glycosylated haemoglobin levels were 265 mg/dL (14.7 mmol/L), 382 mg/dL (21.2 mmol/L) 11.2% (NGSP) (IFCC 98.9 mmol/mol)...
Adrenal myelolipomas are infrequently encountered benign tumours of unknown aetiology. In the majority cases they unilateral, and clinically hormonally silent, only requiring periodic follow-up. However, bilateral adrenal sometimes associated with endocrine disorders warrant appropriate evaluation. Though understanding pathophysiology has long been elusive, adrenocorticotropic hormone (ACTH) proposed as main tropic factor in a number studies. Cushing's disease is rarely giant myelolipomas....