The existence of non-celiac gluten sensitivity has been debated. Indeed, the intestinal and extra-intestinal symptoms many patients with irritable bowel syndrome (IBS) but without celiac disease or wheat allergy have shown to improve on a gluten-free diet. Therefore, this study set out evaluate effects IBS symptoms.We performed double-blind randomized placebo-controlled rechallenge trial in tertiary care hospital who fulfilled Rome III criteria. Patients were appropriately excluded....

Splanchnic venous system thrombosis is a well recognized local vascular complication of acute pancreatitis (AP). It may involve splenic vein (SplV), portal (PV) and superior mesenteric (SMV), either separately or in combinations, often detected incidentally, indeed some cases present with upper gastrointestinal bleed, bowel ischemia hepatic decompensation. Incidence variable depending on study subjects diagnostic modalities. Pathogenesis multifactorial centered systemic inflammation....

Abdominal tuberculosis is an increasing problem in developing world.The objective of the study was to describe clinical presentations, drug resistance pattern and treatment outcomes abdominal Western India.All cases from May 2014 April 2017, diagnosed on basis profile gross morphological findings at endoscopy, imaging, followed by histology and/or GeneXpert MGIT culture were included. All patients received antitubercular (AKT) therapy according national protocol. Patients diagnoses till...

Present study aims to the occurrence of cirrhotic cardiomyopathy and its correlation hepatorenal syndrome by assessing cardiac status in patients with cirrhosis liver healthy controls.Thirty alcoholic cirrhotic, thirty non-alcoholic controls were enrolled for study. Cardiac parameters assessed color doppler echocardiography. Patients followed up twelve months period development syndrome.Mild diastolic dysfunction was present 18 (30%): grade I fifteen II three. Diastolic unrelated age; sex...

The aim of this study was to analyze the natural history and treatment outcomes autoimmune hepatitis (AIH) variants presenting with severe-AIH.Severe acute presentation is an uncommon manifestation AIH, it remains poorly characterized.We included 101 patients AIH from January 2011 December 2015. Patients were classified as seropositive-AIH seronegative-AIH. liver failure, acute-on-chronic severe defined severe-AIH patients. Patient characteristics follow-up until 12 months analyzed between...

Acute kidney injury increases mortality in cirrhotic patients by four fold. This study aimed to determine the usefulness of urinary neutrophil gelatinase-associated lipocalin (uNGAL) for differential diagnosis acute and predicting short-term patients.We enrolled 94 decompensated cirrhosis. uNGAL was measured upon hospital admission all patients. Patients with tract infection anuria were excluded. followed 30 days or until death.Ten (9%) had normal function, 9 (11.37%) stable chronic disease,...

Gastroduodenal tuberculosis is infrequently seen in day-to-day clinical practice with few cases reported the literature. It usually associated features of gastric outlet obstruction. This a case series 4 patients 2 them having lower gastrointestinal involvement. One resembled growth cardia stomach which responded to antitubercular drugs. Another had duodenal erosions portal lymph node enlargement drug treatment. None required surgical management. should be considered high degree suspicion...

We conducted a prospective study to determine the most reliable indicator of common bile duct stones before laparoscopic cholecystectomy. One hundred thirty-seven patients were referred for endoscopic retrograde cholangiography cholecystectomy suspected choledocholithiasis due one or more following abnormalities: (a) altered liver function tests, (b) increased serum amylase levels, (c) dilated (>7 mm) with without evidence on sonography. Sensitivity, specificity, positive and negative...

Solitary rectal ulcer syndrome is a perplexing condition with complex multifactorial pathophysiology. Inappropriate contraction of the puborectalis muscle and mucosal prolapse have been commonly implicated, although self-induced trauma has suspected in some cases. Eight patients who presented bleeding excessive mucus were found to an isolated on proctosigmoidoscopy. Constipation, straining at stools, pain anal region present seven eight All them confessed digitation. Most had consulted more...

Background and Aims: Psychometric hepatic encephalopathy score (PHES) is used widely for diagnosis of minimal (MHE). This prospective study aimed to determine the utility inhibitory control test (ICT) MHE. Additionally, efficacy rifaximin lactulose reversal MHE was evaluated.

ABSTRACT BACKGROUND: Variceal bleeding remains important cause of upper gastrointestinal bleed. Various risk scores are used in stratification for non-variceal Their utility variceal patients is not clear. This study aims to compare probability these predicting various outcomes same population. OBJECTIVE: To characteristics and validate AIMS65, Rockall, Glasgow Blatchford score(GBS), Progetto Nazionale Emorragia Digestiva (PNED) score Upper Gastrointestinal Bleed (UGIB) our METHODS: Three...

Evaluation of mediastinal lymphadenopathy (MLA) is a great diagnostic challenge considering the myriad causes. In recent years, role endoscopic ultrasound (EUS) has been greatly extended in evaluation MLA due to its safety, reliability, and accuracy. The present study details EUS-guided-fine-needle aspiration/fine-needle biopsy (EUS-FNA/FNB) unknown origin.Seventy-two patients (34 men) with etiology were studied. Mediastinum was evaluated linear echoendoscope FNA/FNB performed 22-G needle...

Autoimmune hepatitis (AIH), despite being uncommon, is on the rise in elderly population. However, no study from India has described natural history and treatment outcome of AIH elderly. The aim was to characteristics population compare them with younger population.Patients a diagnosis based revised International Hepatitis Group (IAIHG) criteria were recruited January 2011 June 2018. Patients defined as when ≥ 60 years young < age. Clinical, serological, histological follow-up until 12...

Intestinal involvement in Schistosoma mansoni infection is usually confined to the ileum and colon. Duodenal infestation was diagnosed a patient with recurrent schistosomiasis despite treatment who presented postoperative small bowel fistula. can be suspected on endoscopy, but must always confirmed by biopsy.

Background Coronavirus disease 2019 (COVID-19) infection in chronic liver patients is associated with poor outcomes. In this study, we aimed to evaluate the predictors of severity and mortality group during second wave COVID-19 pandemic India. addition, compared cirrhotic from pre-COVID-19 period. Methodology This was a single-center observational study. We included data 50 cirrhosis retrospectively discharge/death files. A comparison 100 pre-COVID period also analyzed retrospectively....

ABSTRACT BACKGROUND: Hepatitis C virus (HCV) infection is the most common hepatotropic viral affecting patients on maintenance hemodialysis. Treatment of chronic HCV in stage 4 and 5 CKD includes a combination elbasvir/grazoprevir glecaprevir/pibrentasvir, which are not available many countries. OBJECTIVE: Hence, we have conducted this study to look for safety efficacy sofosbuvir therapy difficult treat population. METHODS: We single-center, prospective, open-label Stage hemodialysis with...

of the study: Decompensated hepatitis C virus (HCV) cirrhosis is a difficult to treat cohort, and there no gold standard predictor response direct-acting antiviral (DAA) therapy. We conducted this study look for factors responsible improvement in post-therapy status, i.e. attainment Child-Turcotte-Pugh (CTP) class A from B or C, devise new model predict response.and methods: Prospective analysis data decompensated HCV cirrhotics was done association each parameter with patient outcomes at 36...

Trichuris trichiura ( T. Trichiura) is a known parasite infestation among tropical children. Humans acquire Trichuriasis infection after ingestion of embryonated eggs via contaminated food or water. Most them are asymptomatic. A severe form trichuris as dysentery syndrome (TDS). It manifests mucous diarrhoea, bleeding, malnutrition and stunting, even life-threatening anaemia. We reporting an interesting case 7-year-old girl who presented with bloody diarrhoea for 2 years. Her growth was...

To study the extent of early atherosclerosis in ulcerative colitis (UC) patients by measuring carotid intima-media thickness (CIMT) and correlation between CIMT, serum homocysteine level homeostasis model assessment-insulin resistance (HOMA-IR) UC.We studied 60 UC healthy controls. Individuals with risk factors for were excluded from study. Fasting blood glucose, lipid profile, HOMA-IR, erythrocyte sedimentation rate (ESR), vitamin B12 levels measured all participants. CIMT was using a...

The role of endoscopic therapy after laparoscopic cholecystectomy (LC) was assessed in 62 patients referred for retrograde cholangiopancreatography (ERCP). Patients were because persistent biliary pain, jaundice, abnormal liver function tests, elevated serum amylase, ultrasound the system, or cholangiogram. Diagnostic imaging system 47 (76%) cases. Sonographic abnormalities seen 33 57 (58%) patients: common bile duct (CBD) stones present 10 58 (17%); CBD >7 mm, 22 (38%); and subhepatic fluid...