The existence of non-celiac gluten sensitivity has been debated. Indeed, the intestinal and extra-intestinal symptoms many patients with irritable bowel syndrome (IBS) but without celiac disease or wheat allergy have shown to improve on a gluten-free diet. Therefore, this study set out evaluate effects IBS symptoms.We performed double-blind randomized placebo-controlled rechallenge trial in tertiary care hospital who fulfilled Rome III criteria. Patients were appropriately excluded....

Abdominal tuberculosis is an increasing problem in developing world.The objective of the study was to describe clinical presentations, drug resistance pattern and treatment outcomes abdominal Western India.All cases from May 2014 April 2017, diagnosed on basis profile gross morphological findings at endoscopy, imaging, followed by histology and/or GeneXpert MGIT culture were included. All patients received antitubercular (AKT) therapy according national protocol. Patients diagnoses till...

The aim of this study was to analyze the natural history and treatment outcomes autoimmune hepatitis (AIH) variants presenting with severe-AIH.Severe acute presentation is an uncommon manifestation AIH, it remains poorly characterized.We included 101 patients AIH from January 2011 December 2015. Patients were classified as seropositive-AIH seronegative-AIH. liver failure, acute-on-chronic severe defined severe-AIH patients. Patient characteristics follow-up until 12 months analyzed between...

Esophageal tuberculosis is rare, constituting about 0.3% of gastrointestinal tuberculosis. It presents commonly with dysphagia, cough, chest pain in addition to fever and weight loss. Complications may include hemorrhage from the lesion, development arterioesophageal fistula, esophagocutaneous fistula or tracheoesophageal fistula. There are very few reports esophageal presenting hematemesis due ulceration. We report a patient that was erosion tuberculous subcarinal lymph nodes into...

We describe a case of 42-year-old female presenting with abdominal pain associated loss weight and fever for 8 mo.On evaluation she had gross hepatomegaly raised alkaline phosphatase GGT levels normal transaminases bilirubin.On imaging diffuse enlargement liver heterogeneous contrast uptake in liver.Her viral marker autoimmune markers were negative.Liver biopsy depicted massive deposition amyloid peri-sinusoidal spaces which revealed apple green birefringence on polarizing microscopy after...

Acute kidney injury increases mortality in cirrhotic patients by four fold. This study aimed to determine the usefulness of urinary neutrophil gelatinase-associated lipocalin (uNGAL) for differential diagnosis acute and predicting short-term patients.We enrolled 94 decompensated cirrhosis. uNGAL was measured upon hospital admission all patients. Patients with tract infection anuria were excluded. followed 30 days or until death.Ten (9%) had normal function, 9 (11.37%) stable chronic disease,...

Esophageal duplication cyst is a rare congenital embryonal gastrointestinal (GI) malformation which diagnosed most commonly in childhood. In adults, they can present with variety of symptoms ranging from dysphagia, chest pain, epigastric discomfort, and vomiting to more serious complications including infections, hemorrhage, ulcerations. A 30-year-old male presented gradually progressive dysphagia solids for 4 months without significant weight loss. Clinical examination routine laboratory...

The paediatric obesity is on the rise so as complications of like cardiovascular diseases, liver dyslipidaemia are increasing. changing dietary habits and less outdoor activities risk factors for obesity.The study was conducted to find out prevalence overweight among students in four schools Mumbai compare with studies from rest country.It school based, cross-sectional Schools class 5(th) 10(th). anthropometric measurements height, weight were taken each student. body mass index calculated...

Esophageal squamous cell carcinoma (ESCC) is the commonest primary malignant esophageal tumor, which typically presents as endoscopically visible surface mucosal ulcerations, irregularities, or polyploidal masses. We here report a rare case of ESCC with completely intramural growth under normal looking intact nondysplastic epithelium disguising submucosal tumor. Upper gastrointestinal endoscopy-guided biopsy was negative for malignancy. Endoscopic ultrasound (EUS) revealed heteroechoic solid...

Background and Aims: Psychometric hepatic encephalopathy score (PHES) is used widely for diagnosis of minimal (MHE). This prospective study aimed to determine the utility inhibitory control test (ICT) MHE. Additionally, efficacy rifaximin lactulose reversal MHE was evaluated.

ABSTRACT BACKGROUND: Variceal bleeding remains important cause of upper gastrointestinal bleed. Various risk scores are used in stratification for non-variceal Their utility variceal patients is not clear. This study aims to compare probability these predicting various outcomes same population. OBJECTIVE: To characteristics and validate AIMS65, Rockall, Glasgow Blatchford score(GBS), Progetto Nazionale Emorragia Digestiva (PNED) score Upper Gastrointestinal Bleed (UGIB) our METHODS: Three...

Evaluation of mediastinal lymphadenopathy (MLA) is a great diagnostic challenge considering the myriad causes. In recent years, role endoscopic ultrasound (EUS) has been greatly extended in evaluation MLA due to its safety, reliability, and accuracy. The present study details EUS-guided-fine-needle aspiration/fine-needle biopsy (EUS-FNA/FNB) unknown origin.Seventy-two patients (34 men) with etiology were studied. Mediastinum was evaluated linear echoendoscope FNA/FNB performed 22-G needle...

This was single-center, open-label, randomized trial. Patients who were undergoing ERCP and at high risk for the development of PEP selected study. into 3 treatment groups: diclofenac suppository group, RL a combination group.Eight 57 patients (14.03%) in 9 (15.78%) 6 (10.52%) group developed PEP. The incidence between three groups not statistically significant (P = 0.70). Serum amylase level >252 U/L had 91.3% sensitivity 92.6% specificity diagnosis PEP.Post-ERCP pancreatitis is usually...

Trichuris trichiura ( T. Trichiura) is a known parasite infestation among tropical children. Humans acquire Trichuriasis infection after ingestion of embryonated eggs via contaminated food or water. Most them are asymptomatic. A severe form trichuris as dysentery syndrome (TDS). It manifests mucous diarrhoea, bleeding, malnutrition and stunting, even life-threatening anaemia. We reporting an interesting case 7-year-old girl who presented with bloody diarrhoea for 2 years. Her growth was...

<p class="ABS"><span class="ABS_Bold-Italic" lang="en-GB">Background</span><span class="Bold">:</span> The risk of acquiring hepatitis B virus (HBV) and C (HCV) infections through exposure to blood or its products contact with other body fluids is high amongst health care workers (HCWs). Despite potential risks, a proportion HCWs never get vaccinated. This study aimed investigate the vaccination practices prevalence HBV infection in HCWs. <span...

To study the extent of early atherosclerosis in ulcerative colitis (UC) patients by measuring carotid intima-media thickness (CIMT) and correlation between CIMT, serum homocysteine level homeostasis model assessment-insulin resistance (HOMA-IR) UC.We studied 60 UC healthy controls. Individuals with risk factors for were excluded from study. Fasting blood glucose, lipid profile, HOMA-IR, erythrocyte sedimentation rate (ESR), vitamin B12 levels measured all participants. CIMT was using a...

The spectrum of liver disease among HIV-infected patients is changing. In the era antiretroviral therapy, opportunistic infections are diminishing and deranged function appears to be due usually drug-induced injury, alcohol, non-alcoholic steatohepatitis (NASH) or chronic hepatitis B. To test this hypothesis, 98 HIV-positive with were compared matched normal likewise HIV-negative tests.