A5066894194- Neuroscience and Neural Engineering
- Diamond and Carbon-based Materials Research
- Analytical Chemistry and Sensors
- Advanced Memory and Neural Computing
- Gas Sensing Nanomaterials and Sensors
- Monoclonal and Polyclonal Antibodies Research
- Viral Infectious Diseases and Gene Expression in Insects
- Force Microscopy Techniques and Applications
- Electronic and Structural Properties of Oxides
- Semiconductor materials and devices
- Electrochemical sensors and biosensors
- CAR-T cell therapy research
- Photoreceptor and optogenetics research
- Laser Design and Applications
- Supercapacitor Materials and Fabrication
- Water Quality Monitoring and Analysis
- Conducting polymers and applications
- Advanced Sensor and Energy Harvesting Materials
- Laser Material Processing Techniques
- Fuel Cells and Related Materials
- Nonlinear Optical Materials Studies
- Sensor Technology and Measurement Systems
- Metal and Thin Film Mechanics
- Semiconductor Lasers and Optical Devices
- Electron and X-Ray Spectroscopy Techniques
The University of Melbourne
2018-2025
Pfizer (United States)
2022
University of York
1989
Abstract This study presents a semiconducting optoelectronic system for light‐controlled non‐genetic neuronal stimulation using visible light. The architecture is entirely wireless, comprising thin film of nitrogen‐doped ultrananocrystalline diamond directly grown on silicon substrate. When immersed in physiological medium and subjected to pulsed illumination the (595 nm) or near‐infrared wavelength (808 range, charge accumulation at device‐medium interface induces transient ionic...
Durable and safe energy storage is required for the next generation of miniature bioelectronic devices, in which aqueous electrolytes are preferred due to advantages safety, low cost, high conductivity. While rechargeable batteries among primary choices with relatively power requirements, their lifetime generally limited a few thousand charging/discharging cycles as electrode material can degrade electrochemical reactions. Electrical double layer capacitors (EDLCs) possess increased cycling...
This study demonstrates the control of neuronal survival and development using nitrogen-doped ultrananocrystalline diamond (N-UNCD). We highlight role N-UNCD in regulating activity via near-infrared illumination, demonstrating generation stable photocurrents that enhance neurite outgrowth foster a more active, synchronized network. Whole transcriptome RNA sequencing reveals substrates improve cellular–substrate interaction by upregulating extracellular matrix gap junction-related genes. Our...
In recent years, various forms of nanocrystalline diamond (NCD) have emerged as an attractive group diamond/graphite mixed-phase materials for a range applications from electron emission sources to electrodes neural interfacing. To tailor their properties different uses, NCD surfaces can be terminated with chemical functionalities, in particular hydrogen and oxygen, which shift the band edge positions affinity values. While chemically single crystal are well understood, same is not true...
Semiconducting electrodes are increasingly utilised for neural interfacing applications, such as recording, stimulation, and photomodulation. To characterize the performance of these electrodes, photoelectrochemical analysis is often undertaken in biologically relevant electrolytes. These include electrochemical impedance spectroscopy (EIS), cyclic voltammetry (CV), photomodulation photocurrent (PC) measurements. From measurements, it possible to deduce key properties semiconductor surfaces,...
The ability to form diamond electrodes on insulating polycrystalline substrates using single-step laser patterning, and the use of as a substrate that supports adhesion proliferation human mesenchymal stem cells (hMSCs) is demonstrated. Laser induced graphitisation results in conductive amorphous carbon surface, rich oxygen nitrogen terminations. This an electrode with high specific capacitance 182 uF/cm2, wide water window 3.25 V, low electrochemical impedance 129 Ohms/cm2 at 1 kHz. surface...
Views Icon Article contents Figures & tables Video Audio Supplementary Data Peer Review Share Twitter Facebook Reddit LinkedIn Tools Reprints and Permissions Cite Search Site Citation A. Chambers; An inexpensive ‘‘shuttered viewport’’ device. J. Vac. Sci. Technol. A 1 March 1989; 7 (2): 259–260. https://doi.org/10.1116/1.576130 Download citation file: Ris (Zotero) Reference Manager EasyBib Bookends Mendeley Papers EndNote RefWorks BibTex toolbar search Dropdown Menu input auto suggest filter...
Abstract Site‐specific integration (SSI) cell line systems are gaining popularity for biotherapeutic development and production. Despite the proven advantages these expression hosts, SSI system is still susceptible to rare off‐target events potential vector rearrangements. Here we describe process of an production IgG1 monoclonal antibody (mAb‐086). During generational studies assess suitability clone C10 commercial purposes, restriction fragment lengths genomic DNA harboring light chain...
Electrical stimulation is one of several methods for controlling differentiation and proliferation stem cells. This work demonstrated the use nitrogen-doped ultra-nanocrystalline diamond (N-UNCD) electrodes as a substrate growth human mesenchymal cells (hMSCs). As well exhibiting high charge injection capacity, N-UNCD displays cytocompatibility making it suitable electrode material cell stimulation.Clinical Relevance—This establishes that can support hMSCs.
Nitrogen-doped ultrananocrystalline diamond (N-UNCD) is a promising material for variety of neural interfacing applications, due to its unique combination high conductivity, bioinertness, and durability. One emerging application N-UNCD as photoelectrode high-precision optical stimulation. This may be used the treatment neurological disorders implantable bionic devices such cochlear ear implants retinal prostheses. well-suited stimulation photoelectrodes, exhibiting photocurrent response...