Shuangqing Li

ORCID: 0000-0001-7208-2015
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About
Contact & Profiles
Research Areas
  • Liver Disease Diagnosis and Treatment
  • Thyroid Disorders and Treatments
  • Diabetes Treatment and Management
  • Conducting polymers and applications
  • Lipid metabolism and disorders
  • Diabetes, Cardiovascular Risks, and Lipoproteins
  • Growth Hormone and Insulin-like Growth Factors
  • Metabolism, Diabetes, and Cancer
  • Adipokines, Inflammation, and Metabolic Diseases
  • Advanced Sensor and Energy Harvesting Materials
  • ZnO doping and properties
  • Diet, Metabolism, and Disease
  • Cancer, Hypoxia, and Metabolism
  • Diet and metabolism studies
  • Hepatitis B Virus Studies
  • Gout, Hyperuricemia, Uric Acid
  • Regulation of Appetite and Obesity
  • Nutrition and Health in Aging
  • Body Composition Measurement Techniques
  • Fibroblast Growth Factor Research
  • Bone health and osteoporosis research
  • Copper-based nanomaterials and applications
  • Supercapacitor Materials and Fabrication
  • Diabetes Management and Research
  • Ga2O3 and related materials

Bohai University
2024-2025

Gannan Normal University
2025

West China Medical Center of Sichuan University
2020-2024

West China Hospital of Sichuan University
2013-2024

Jinhua Central Hospital
2013-2024

Zhejiang University
2024

Sichuan University
2013-2024

Zhengzhou University
2020-2024

Wuhan National Laboratory for Optoelectronics
2024

Huazhong University of Science and Technology
2023-2024

Background Sarcopenia, common in the elderly, often linked to chronic diseases, correlates with inflammation.The association between SII and mortality sarcopenia patients is underexplored, this study investigates relationship a U.S. adult cohort. Methods We analyzed 1999–2018 NHANES data, focusing on 2,974 adults sarcopenia. Mortality outcomes were determined by linking National Death Index (NDI) records up December 31, 2019. Using weighted sampling design, participants grouped into three...

10.3389/fimmu.2024.1376544 article EN cc-by Frontiers in Immunology 2024-04-04

Globally, cardiovascular disease (CVD) constitutes the primary cause of death, with insulin resistance (IR), measured by triglyceride-glucose (TyG) index, and visceral obesity, reflected Chinese Visceral Adiposity Index (CVAI), as key contributors. However, relationship between TyG index CVAI regarding CVD risk remains insufficiently understood. This research investigates interactive impact on disease. We analyzed data from 8,358 participants China Health Retirement Longitudinal Study...

10.1186/s12933-024-02518-2 article EN cc-by-nc-nd Cardiovascular Diabetology 2024-11-27

Background Oxidative Balance Score (OBS) is a novel indicator of the overall antioxidant/oxidant balance, providing comprehensive reflection body’s oxidative stress status, with higher OBS suggesting more substantial antioxidant exposures. We aimed to investigate possible relationship between serum uric acid (SUA) and hyperuricemia. Methods Data utilized in this study were sourced from 2011–2018 National Health Nutrition Examination Survey (NHANES). Participants under 18 years old, those ≤16...

10.3389/fendo.2024.1414075 article EN cc-by Frontiers in Endocrinology 2024-06-20

Abstract Background The triglyceride and glucose index (TyG) to high-density lipoprotein cholesterol ratio (TG/HDL-C) are substitute markers of insulin resistance (IR). In a retrospective cross-sectional study, the authors aimed compare efficacy two indicators in diagnosing metabolic-associated fatty liver disease (MAFLD) construct novel diagnosis model. Methods Overall, 229 patients (97 MAFLD 132 Non-MAFLD at West China Hospital Sichuan University were included. was diagnosed using...

10.1186/s12944-022-01661-7 article EN cc-by Lipids in Health and Disease 2022-06-25

Background Depression and the increased risk of sarcopenia are prevalent among elderly population. However, causal associations between these factors remain unclear. To investigate potential association depression in older adults, this study was performed. Methods In baseline survey, a total 14,258 individuals aged 40 above from China Health Retirement Longitudinal Study (2015) participated. We initially described prevalence disease. Then, logistic regression restricted cubic spline (RCS)...

10.3389/fpsyt.2023.1263553 article EN cc-by Frontiers in Psychiatry 2023-10-18

Abstract Background Hypoxia-inducible transcription factor-1α (HIF-1α), which plays an important role in controlling the hypoxia-induced glycolysis pathway, is a "master" gene tissue hypoxia response during tumor development. However, its apoptosis of non-small cell lung cancer remains unknown. Here, we have studied effects HIF-1α on by modulating expression A549 cells through both siRNA knock-down and over-expression. Methods were transfected with plasmid or vector. Transfected exposed to...

10.1186/1471-2407-6-26 article EN cc-by BMC Cancer 2006-01-27

A growing body of research has demonstrated that the degeneration chondrocytes is primary cause osteoarthritis (OA). Parathyroid hormone-related protein (PTHrP) can alleviate via promotion chondrocyte proliferation and inhibition terminal differentiation, but underlying mechanism remains unknown. This study aimed to identify microRNAs (miRNAs) may target PTHrP regulate differentiation chondrocytes.Bioinformatic analysis was used predict which miRNAs PTHrP. We collected human knee cartilage...

10.1155/2019/3904923 article EN BioMed Research International 2019-03-05
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