A5030746324- Genetic and phenotypic traits in livestock
- Genetic Mapping and Diversity in Plants and Animals
- Cancer-related molecular mechanisms research
- Animal Genetics and Reproduction
- Veterinary Equine Medical Research
- Reproductive Physiology in Livestock
- Genomics and Phylogenetic Studies
- Meat and Animal Product Quality
- Genetic diversity and population structure
- Genetics and Plant Breeding
- Molecular Biology Techniques and Applications
- Effects of Environmental Stressors on Livestock
- Muscle metabolism and nutrition
- Agricultural Systems and Practices
- Animal Behavior and Welfare Studies
- Animal Nutrition and Physiology
- Animal Disease Management and Epidemiology
- Livestock Farming and Management
- Genetics and Physical Performance
- Identification and Quantification in Food
- Livestock and Poultry Management
- Toxoplasma gondii Research Studies
- Vector-Borne Animal Diseases
- Neurogenetic and Muscular Disorders Research
- Genetics, Aging, and Longevity in Model Organisms
The University of Queensland
2019-2024
The University of Sydney
2014-2019
Discerning the traits evolving under neutral conditions from those rapidly because of various selection pressures is a great challenge. We propose new method, composite signals (CSS), which unifies multiple pieces evidence rank distribution its diverse constituent tests. The extreme CSS scores capture highly differentiated loci and underlying common variants hauling excess haplotype homozygosity in samples target population. data on high-density genotypes were analyzed for an association...
Abstract Background Thousands of years natural and artificial selection since the domestication horse has shaped distinctive genomes Chinese Mongolian populations. Consequently, genomic signatures can provide insights into human-mediated history specific traits evolutionary adaptation to diverse environments. Here, we used genome-wide SNPs from five distinct populations identify regions under for population-specific traits, gait, black coat colour, hoof quality. Other global breeds were...
Understanding the evolution and molecular architecture of complex traits is important in domestic animals. Due to phenotypic selection, genomic regions develop unique patterns genetic diversity called signatures which are challenging detect, especially for polygenic traits. In this study, we applied composite selection signals (CSS) method investigate evidence positive a trait by examining stature phenotypically diverse cattle comprising 47 European 8 African Bos taurus breeds, utilizing...
Abstract Background Insulin dysregulation (ID) is central to equine metabolic syndrome. There are limited epidemiological studies investigating dynamic testing of ID in ponies. Objectives To evaluate prevalence and risk factors for through hyperinsulinaemia (DHI) insulin resistance (IR). Study design Cross‐sectional. Methods Sex, age, breed, height, cresty neck score (CNS), body condition (BCS), laminitis, HMGA2 :c.83G>A genotype pituitary pars intermedia dysfunction (PPID) status were...
Kerry cattle are an endangered landrace heritage breed of cultural importance to Ireland. In the present study we have used genome-wide SNP array data evaluate genomic diversity within population and between other European breeds. Patterns genetic differentiation gene flow among breeds using phylogenetic trees with ancestry graphs highlighted historical from British Shorthorn into ancestral modern cattle. Principal component analysis (PCA) clustering emphasised distinctiveness relative...
Extensively grazed cattle are often mustered only once a year. Therefore, birthdates typically unknown or inaccurate. Birthdates would be useful for deriving important traits (growth rate; calving interval), breed registrations, and making management decisions. Epigenetic clocks use methylation of DNA to predict an individual’s age. An epigenetic clock could provide solution the challenges industry birthdate recording. Here we derived first tropically adapted using portable sequencing...
Criollo cattle, the descendants of animals brought by Iberian colonists to Americas, have been subject natural and human-mediated selection in novel tropical agroecological zones for centuries. Consequently, these breeds evolved distinct characteristics such as resistance diseases exceptional heat tolerance. In addition European taurine (
Dehorning is the process of physically removing horns to protect animals and humans from injury, but costly, unpleasant, faces increasing public scrutiny. Genetic selection for polled (hornless), which genetically dominant horned, a long-term solution eliminate need dehorning. However, due limited number Australian Brahman bulls, northern beef cattle population remains predominantly horned. The potential use gene editing produce high-genetic-merit was recently demonstrated. To further...
Breeding for polled animals is deemed the most practical solution to eradicate horns naturally and circumvent management costs risks on health welfare. However, there has been a historical reluctance by some farmers select due perceived lower productivity of their calves. This study compared estimated breeding values (EBVs) between horned (N = 2,466,785) 12 production carcass traits assess (before 2000) recent (2000–2018) genetic implications poll breeding. Older generations in breeds had...
Abstract Many breeds of modern cattle are naturally horned, and for sound husbandry management reasons the calves frequently undergo procedures to physically remove horns by disbudding or dehorning. These however a welfare concern. Selective breeding polledness – absence has been effective in some but not others (Bos indicus genotypes) due part complex genetics horn phenotype. To address this problem different approaches genetic testing which provide accurate early-in-life prediction...
Most traits in livestock, crops and humans are polygenic, that is, a large number of loci contribute to genetic variation. Effects at these lie along continuum ranging from common low-effect rare high-effect variants cumulatively the overall phenotype. Statistical methods calculate effect have been developed can be used predict phenotypes new individuals. In agriculture, select superior individuals using genomic breeding values; quantitatively measure an individual's disease risk, termed...
Thoroughbred horse racing is a global sport with major hubs in Europe, North America, Australasia and Japan. Regional preferences for certain traits have resulted phenotypic variation that may result from adaptation to the local ecosystem. Here, we test hypothesis genes selected regional be identified by analysis of selection signatures pan-genomic SNP genotype data. Comparing Australian non-Australian horses (n = 99), most highly differentiated loci composite signals (CSS) were on ECA6...
The Galway sheep population is the only native Irish breed and this livestock genetic resource currently categorised as "at-risk". In present study, comparative genomics analyses of other populations European origin were used to investigate microevolution recent history breed. These support hypothesis that British Leicester in formation Galway. When compared conventional endangered breeds, was intermediate effective size, genomic inbreeding runs homozygosity. This indicates that, although...
Vietnamese smallholder dairy cows (VDC) are the result of crossbreeding between different zebu (ZEB) and taurine breeds through many undefined generations. Thus, predominant breed composition VDC is currently unknown. This study aimed to evaluate level genetic diversity VDC. The SNP data 344 animals from 32 farms located across four regions Vietnam were collected merged with genomic reference data, which included three ZEB breeds: Red Sindhi, Sahiwal Brahman, Holstein (HOL), Jersey (JER)...
Bovine trichomoniasis, caused by the protozoal parasite Tritrichomonas foetus, is a highly contagious venereal disease characterised early pregnancy loss, abortion and pyometra. Persistently infected bulls cows are primary reservoirs of infection in herds. This research investigated prevalence T. foetus from properties located across northern Australia New South Wales. Preputial samples were collected 606 at slaughter tested for using VetMAX-Gold Trich Detection Kit (Thermo Fisher...
ABSTRACT Genomic selection (GS) and genome‐wide association studies (GWAS) have not been investigated in Vietnamese dairy cattle, even for basic milk production traits, largely due to the scarcity of individual phenotype recording smallholder farms (SDFs). This study aimed estimate heritability ( h 2 ) test applicability GS GWAS production, body conformation novel heat tolerance traits using single day phenotypic data. Thirty‐two SDFs located either north (a lowland vs. a highland) or south...
Abstract Most traits in livestock, crops and humans are polygenic, that is, a large number of loci contribute to genetic variation. Effects at these lie along continuum ranging from common low-effect rare high-effect variants cumulatively the overall phenotype. Statistical methods calculate effect have been developed can be used predict phenotypes new individuals. In agriculture, select superior individuals using genomic breeding values; quantitatively measure an individual’s disease risk,...