<p style="text-align: justify;"><strong>Objective:</strong> The study is to evaluate Yemeni medical and pharmacy students&rsquo; knowledge attitude regarding generic medicines. <strong>Method:</strong> A cross-sectional survey was used collect data from final-year students at six public private universities in Yemen. questionnaire distributed among the through their course coordinators. Students were clearly informed about objective of written consents taken before survey. responses entered...

This study provides the first investigation on occurrence of human pharmaceuticals in tropical aquatic environment Malaysia. Water samples were collected at seven different sites along Langat River and effluents from five sewage treatment plants (STPs) Basin. Samples extracted by solid phase extraction (SPE) analyzed using liquid chromatography coupled with a tandem mass spectrometry (LC-MS/MS) for 18 six therapeutic classes one metabolite. Fifteen out these 19 detected river water samples....

Aflatoxin B1 (AFB1) is a significant pollutant found in food and feed, posing threat to public health. The objective of this study was assess the effect Lactiplantibacillus plantarum (LACP) against AFB1 growing rabbits by investigating growth, serum metabolites, immunity, antioxidant capacity, inflammatory response. A total 60 male (721.5±2.68g) were allocated four experimental groups. control group receiving only basal diet, (0.3 mg AFB1/kg diet), LACP (1×109 cfu/g /kg combination + 0.3...

Objective: This study aimed to investigate the learning style preferences of dental students in their first and fifth academic years using VARK model identify potential changes over time. Methods: A cross-sectional was conducted among first- fifth-year undergraduate at University Science Technology, Aden, Yemen. The Arabic version questionnaire, comprising 16 multiple-choice questions, administered via Google Forms. Results: total 86 participated study, with a response rate 38.1%. Both...

Objective: This study examines the prevalence of interest among Yemeni pharmacy graduates in pursuing a master's degree and validates culturally sensitive questionnaire designed for same purpose. Method: A cross-sectional was conducted using an online distributed to 123 or their final year study. Data collected via Google form period between June – July 2024. Participants were either students pharmacy. The survey validated pilot analyzed by SPSS version 26. Results: indicated that majority...

Advances in microbiome profiling technologies enable the assessment of individual gut microbiota composition, paving way for personalized drug therapy. Tailoring medications based on a patient’s could enhance efficacy and minimize side effects. Pharmacogenomics, combined with analysis, lead to more accurate predictions responses optimized treatment plans. In this review, we explore relationship between metabolism microbiome, specific focus enzymatic processes how bacteria metabolize drugs,...

Monosodium glutamate (MSG) is commonly used worldwide as a food flavour enhancer by the industry. The current study investigated in vivo toxic effects of MSG on uterus adult female Sprague Dawley rats and vitro using MCF-7 MDA-MB-231 cells, computational toxicity molecular docking. average levels progesterone oestrogen MSG-treated animals significantly altered. Besides, uterine lumen area (μm2) was smaller than control group. showed high-affinity binding to acetylcholine receptors disrupted...

&lt;i&gt;Artemisia herba-alba &lt;/i&gt;(AHA), known as sheeh in Jordan, is recommended by regional traditional healers for the treatment of a variety diseases. AHA&lt;i&gt; &lt;/i&gt;has been used folk medicine to treat colds, coughing, bronchitis, intestinal disturbances, diarrhea, neuralgias, arterial hypertension, and diabetes. The objectives current study were identify chemical compositions essential oil extracted from dried leaf powder AHA cultivated Jordan investigate its...

Curcumin (CUR) has been used since ancient times to treat several ailments as it possesses many pharmacological activities. This study intended explore the mechanism underlying protective effects of CUR in remodeling oxidative stress and apoptotic signals cyclophosphamide (CP)-induced pulmonary injury albino rats. was administered at a dose 300 mg/kg/day for 7 days on seventh day single CP (200 mg/kg) given. Histopathological ultrastructural examinations CP-intoxicated rats showed complete...

Melatonin is one of the most versatile and ubiquitous molecule widely distributed in nature has been reported to play a role wide variety physiological responses including reproduction, circadian homeostasis, sleep, retinal neuromodulation, vasomotor responses. In vertebrates, humans, melatonin synthesized primarily pineal gland regulated by environmental light ⁄ dark cycle via suprachiasmatic nucleus. all areas body such as gastrointestinal tract, skin, bone marrow, retina lymphocytes, from...

Abstract The development of natural insecticide from plant products may have a beneficial effect as promising candidate for practical strategies controlling vector‐borne diseases without current treatment. present study was carried out to characterize green synthesized metallic nanomaterials silver (Ag‐NPs) and gold (Au‐NPs) extract leaf Nerium oleander L., assess in vivo toxicity, evaluate the larvicidal activity against Aedes aegypti . prepared (Ag‐NPs Au‐NPs) were characterized by...

5 Abstract: The objective of this study was to determine the use complementary and alternative medicine (CAM) among cancer patients in Malaysia. A cross-sectional carried out at two Malaysian referral hospitals. questionnaire consisted 28 items includes patients' socio-demographic characteristics, clinical characteristics questions about CAM use. total number 200 participated study. majority were female, Malay, married, with tertiary education working (54.5%, 36.5%, 53.5%, 46.5%, 45.0%;...

Understanding current perceptions of medical students regarding learning pharmacology and understanding pharmacology's important role in both clinical practice research may be helpful improving the teaching this discipline. This study was conducted to evaluate students' opinions toward pharmacology. One hundred fifty students, randomly selected from Management Sciences University (MSU) Malaysia, completed a self-administered questionnaire that inquired concerning their views The majority...

Novel mononuclear complexes 2–8 derived from hybrid Urea Schiff base HL were synthesized using various metal Ni2+, Fe3+, Cu2+, Co2+, Mn2+, Zn2+, and Cr3+. The results revealed the ligand reacts with ions as monobasic or neutral monodentate chelator it via nitrogen of azomethine deprotonated/protonated phenolic oxygen atom adopting octahedral geometry. elemental analysis showed bonding in a ratio 1: 1 all-metal complexes. XRD its indicate monoclinic, tetragonal, orthorhombic corresponding to...

13α,21-Dihydroeurycomanone (1), a known quassinoid of Eurycoma longifolia Jack was recrystallized from chloroform into novel crystal structure in space group P21. Its X‐ray data were compared with those eurycomanone (2). Following intraperioneal injections at similar doses 2.44 µmol/kg/day for 3 consecutive days, 2 displayed comparable potency tamoxifen but more potent than 1 the anti-estrogenic effect against 17α-ethynylestradiol (EE)-induced uterotrophy immature rats.

The objective of this study was to explore the knowledge and perceptions Malaysian tradition healers towards cancer prevention.A total 25 participants agreed participate in qualitative during period from 20th July 2011 until 24th September 2011. proposal approved by Ethics Committee Management Science University (MSU). Once participant be interviewed, date, time place interviews were determined. Consent form obtained before interview began. Participants briefed about its purpose, after...

Background: Ganoderma lucidum spores (GLS) exhibit disease prevention properties, but no study has been carried out on the anti-diabetic cardiomyopathy property of GLS. The aim this was to evaluate hyperglycemia-mediated protection and mechanisms GLS in streptozotocin (STZ)induced diabetic rats. Methods: Male SD rats were randomly divided into three groups. Two groups given STZ (50 mg/kg, i.p.) treatment when their fasting plasma glucose above 16.7 mmol/L, among them, one group placebo, as...

Thymoquinone (TQ), the active constituent of Nigella sativa , possesses several benefits in traditional and modern medicines. This study examined effect a single dose Nano‐TQ on chronic lung injury induced by repetitive intratracheal installation lipopolysaccharide (LPS). Rats received LPS twice weekly for 8 weeks via TQ‐PLGA NPs day after last LPS. Six rats from each group were sacrificed 10 weeks, samples collected analysis. Repetitive caused histopathological alterations, including...