Pseudomonas sp. phDV1 is a polyhydroxyalkanoate (PHA) producer. The presence of the endogenous PHA depolymerase (phaZ) responsible for degradation intracellular one main shortages in bacterial production PHA. Further, can be affected by regulatory protein phaR, which important accumulating different PHA-associated proteins. phaZ and phaR knockout mutants were successfully constructed. We investigate from 4.25 mM phenol grape pomace wild type. was screened fluorescence microscopy, quantified...

The cognitive and affective impacts of video games are subjects ongoing debate, with recent research recognizing their potential benefits. This study employs the Gaming Skill Questionnaire (GSQ) to evaluate participants’ gaming skills across six genres overall proficiency. A total 88 individuals aged 20–40 participated, completing assessments empathy abilities: verbal short-term memory, working visuospatial psychomotor speed (hand–eye coordination), attention. Participants’ abilities were...

The cognitive and affective impacts of video games are subjects ongoing debate, with recent research recognizing their potential benefits. This study employs the Gaming Skill Questionnaire (GSQ) to evaluate participants’ gaming skills across six genres overall proficiency. A total 88 individuals aged 20–40 participated, completing assessments empathy abilities: verbal short-term memory, working visuospatial psychomotor speed (hand–eye coordination), attention. Participants’ abilities were...

The cognitive and affective impacts of video games are subjects ongoing debate, with recent research recognizing their potential benefits. This study employs the Gaming Skill Questionnaire (GSQ) to evaluate participants' gaming skills across six genres overall proficiency. Eighty-eight individuals aged 20-40 participated, completed assessments empathy abilities: verbal short-term memory, working visuospatial psychomotor speed (hand-eye coordination), attention. Cognitive abilities...

In order to address pathological cognitive decline effectively, it is critical adopt early preventive measures in individuals considered at risk. It therefore essential develop approaches that identify such before the onset of irreversible dementia. A deficient cholinergic system has been consistently implicated as one main factors associated with a heightened vulnerability aging process. present study we used mice lacking high affinity nicotinic receptors (β2-/-), which have proposed an...

Evaluating depressive symptomatology in older adults is important for monitoring and treatment. However, few studies have examined the association of Beck Depression Inventory-II (BDI-II) to demographic characteristics middle-aged or tested its factor structure using confirmatory analysis (CFA). Participants were 542 Greek community-dwellers a wide education range. The BDI-II score was correlated with age one-way variance compared mean men women, controlling differences education. In...

The cognitive and affective impacts of video games are subjects ongoing debate, with recent research recognizing their potential benefits. This study employs the Gaming Skill Questionnaire (GSQ) to evaluate participants' gaming skills across six genres overall proficiency. Eighty-eight individuals aged 20-40 participated, completed assessments empathy abilities: verbal short-term memory, working visuospatial psychomotor speed (hand-eye coordination), attention. Cognitive abilities were...

The mechanisms by which aging leads to alterations in brain structure and cognitive deficits are unclear. Α deficient cholinergic system has been implicated as one of the main factors that could confer a heightened vulnerability process, mice lacking high-affinity nicotinic receptors (β2−/−) have proposed an animal model accelerated aging. To date, however, age-related changes neuronal microanatomy not studied these mice. In present study, we examine yellow fluorescent protein (YFP+) layer V...

Several molecular and cellular processes in the vertebrate brain exhibit differences between males females, leading to sexual dimorphism formation of neural circuits organization. While studies on large-scale networks provide ample evidence for both structural functional sex differences, smaller-scale local have remained largely unexplored. In current study, we investigate cortical dynamics by means spontaneous Up/Down states, a type network activity that is exhibited during slow-wave sleep,...

Amyotrophic Lateral Sclerosis (ALS) is the most common motor neuron disease and clinically defined by degeneration of upper lower neurons, leading to paralysis premature death. 10% ALS patients suffer from familial form research has revealed a number responsible mutations in specific genes loci. Transgenic mouse models carrying human related have been generated for study mechanisms involved pathogenesis putative therapies. Mutations Cu/ Zn superoxide dismutase 1 (SOD1) gene, accounting 20%...

Event Abstract Back to Premature aging phenotype in mice lacking high affinity nicotinic receptors: region specific changes layer V pyramidal cell morphology Eleni Konsolaki1* and Irini Skaliora1 1 Biomedical Research Foundation of the Academy Athens, Division Developmental Biology, Greece The mechanisms by which leads alterations brain structure cognitive deficits are unclear. A central yet presently unresolved issue research concerns distinction between normal/successful aging, consisting...

Observational fear-learning studies in genetically modified animals enable the investigation of mechanisms underlying social transmission fear-related information. Here, we used a three-day protocol to examine fear conditioning by proxy (FCbP) wild-type mice (C57BL/6J) and lacking β2-subunit nicotinic acetylcholine receptor (nAChR). Male both genotypes were exposed previously fear-conditioned (FC) cage mate during presentation conditioned stimulus (CS, tone). On following day, observer...