About
A5116633564University of California, Berkeley
2025
Genome regulation relies on complex and dynamic interactions between DNA proteins. Recently, powerful methods have emerged that leverage third-generation sequencing to map protein-DNA genome-wide. For example, Directed Methylation with Long-read (DiMeLo-seq) enables mapping of along long, single chromatin fibers, including in highly repetitive genomic regions. However, DiMeLo-seq involves lossy centrifugation-based wash steps limit its applicability many sample types. To address this, we...
10.1101/2025.03.11.642717
preprint
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cc-by
bioRxiv (Cold Spring Harbor Laboratory)
2025-03-14
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