A5064412974- Corrosion Behavior and Inhibition
- Magnesium Alloys: Properties and Applications
- Crystallization and Solubility Studies
- Bone Tissue Engineering Materials
- X-ray Diffraction in Crystallography
- interferon and immune responses
- Titanium Alloys Microstructure and Properties
- Surface Treatment and Coatings
- Hydrogen embrittlement and corrosion behaviors in metals
- Metal and Thin Film Mechanics
- Virus-based gene therapy research
- DNA and Nucleic Acid Chemistry
- Particle Accelerators and Free-Electron Lasers
- Cytokine Signaling Pathways and Interactions
- Advancements in Materials Engineering
- Crystallography and molecular interactions
- Molecular Sensors and Ion Detection
- Luminescence and Fluorescent Materials
- High-Temperature Coating Behaviors
- Electrodeposition and Electroless Coatings
- Cancer, Hypoxia, and Metabolism
- Synthesis and Properties of Aromatic Compounds
- Particle Detector Development and Performance
- ATP Synthase and ATPases Research
- Advanced Data Storage Technologies
Samsung (Poland)
2022
Medical University of Warsaw
2021
Koszalin University of Technology
2015-2020
SOLARIS National Synchrotron Radiation Centre
2018
Jagiellonian University
2009-2015
Faculty (United Kingdom)
2014
University School of Physical Education in Kraków
2014
AGH University of Krakow
2013
The University of Texas Health Science Center at San Antonio
2008
In the paper, Scanning Electron Microscopy (SEM) with Energy Dispersive X-ray Spectroscopy (EDS) and Photoelectron (XPS) results of surface layer formed on pure titanium after plasma electrolytic oxidation (micro arc oxidation) at voltage 450 V are shown. As an electrolyte, mixture copper nitrate Cu(NO₃)₂ (10-600 g/L) in concentrated phosphoric acid H₃PO₄ (98 g/mol) was used. The thickness obtained porous equals about 10 μm, it consists mainly phosphates oxygen embedded ions as a...
In the paper, glow discharge optical emission spectroscopy, X-ray photoelectron scanning electron microscopy, and energy-dispersive spectroscopy results of a commercial purity titanium grade 2 after plasma electrolytic oxidation (PEO), also known as micro arc (MAO), are presented. The PEO treatment was performed in electrolyte containing concentrated (85%) phosphoric acid with copper nitrate at voltage 450 ± 10 V for 1 min. For electrolyte, addition from 300 to 600 g/l used. Porous coatings...
In this paper, the characteristics of new porous coatings fabricated at three voltages in electrolytes based on H3PO4 with calcium nitrate tetrahydrate, magnesium hexahydrate, and copper(II) trihydrate are presented. The SEM, energy dispersive spectroscopy (EDS), glow discharge optical emission (GDOES), X-ray photoelectron (XPS), XRD techniques for coating identification were used. It was found that higher plasma electrolytic oxidation (PEO) (micro arc (MAO)) voltage, thicker amounts...
In the paper, effect of voltage increase (from 500 VDC up to 650 VDC) on structure and chemical composition porous coating titanium made by Plasma Electrolytic Oxidation is presented. Phosphates-based coatings enriched with calcium, magnesium, zinc, copper in electrolyte based 1 L 85% concentrated H3PO4, additions Ca(NO3)2·4H2O, Mg(NO3)2∙6H2O, Zn(NO3)2∙6H2O, Cu(NO3)2∙3H2O, are described. The morphology phase evaluated using SEM, EDS, XRD, XPS, GDOES, CLSM. Based these analyses, it was found...
Abstract Energy and biomass production in cancer cells are largely supported by aerobic glycolysis what is called the Warburg effect. The process regulated key enzymes, among which phosphofructokinase PFK‐2 plays a significant role producing fructose‐2,6‐biphosphate; most potent activator of rate‐limiting step performed PFK‐1. Herein, synthesis, biological evaluation structure–activity relationship novel inhibitors 6‐phosphofructo‐2‐kinase/fructose‐2,6‐biphosphatase 3 (PFKFB3), ubiquitous...
Analysis of the spectral properties and structural differences two turn-on ratiometric fluorescent receptors for Zn2+ Cd2+ ions, derivatives pyrrolo[2,3-b]quinoxaline (2), earlier published 3 (Ostrowska et al. CrystEngComm 2015, 17, 498–502) was performed. Both ligands are E/Z push–pull olefins interconverting at room temperature, with barriers to rotation about enamine double bonds, from E Z isomers 19.3 ± 0.1 16.9 0.3 kcal/mol 15.7 0.2 kcal/mol, respectively. Diastereoisomers (E)-2 (Z)-2...
Among three novel DBTAA derivatives only the DBTAA–propyl–adenine conjugate 1 showed recognition of consecutive oligo dT sequence by increased affinity and specific induced chirooptical response in comparison to other single stranded RNA DNA; whereby particular importance is up until now unique efficient differentiation between rU. At variance, its close analogue DBTAA–hexyl–adenine 2 did not reveal any selectivity ss-DNA/RNA pointing out important role steric factors (linker length);...
Due to increased lactate production during glucose metabolism, tumor cells heavily rely on efficient transport avoid intracellular accumulation and acidification. Monocarboxylate transporter 4 (MCT4/SLC16A3) is a that plays central role in pH modulation. The discovery optimization of novel class MCT4 inhibitors (hit 9a), identified by cellular screening MDA-MB-231, described. Direct target interaction the optimized compound 18n with cytosolic domain was shown after solubilization GFP-tagged...
Abstract In the paper, surface layers formed on nickel-titanium alloy during Plasma Electrolytic Oxidation (PEO), known also as Micro Arc (MAO), are described. The mixture of phosphoric acid and copper nitrate electrolyte for all plasma electrochemical processes was used. Nitinol biomaterial used studies. All experiments were performed under voltage 450 V current density 0.3 A/dm 2 . main purpose studies to achieve highest amount in layer versus acid. concentration found after PEO treatment...
To fabricate porous copper coatings on titanium, we used the process of plasma electrolytic oxidation (PEO) with voltage control. For all experiments, three-phase step-up transformer six-diode Graetz bridge was used. The and amount salt in electrolyte were determined so as to obtain coatings. Within framework this study, PEO carried out at a 450 VRMS four electrolytes containing copper(II) nitrate(V) trihydrate. Moreover, showed that content needed coating range 300–600 g/dm3. After...
Studied dicationic dibenzotetraaza[14]annulene derivatives intercalate into synthetic double stranded DNA and RNA, while their positively charged side-chains additionally interact within the minor groove of polynucleotides, contributing to overall affinity compounds controlling pronounced A–T(U) over G–C sequence preference as well stronger thermal stabilization ds-DNA than ds-RNA. Furthermore, all showed moderate high antiproliferative activity against five human tumour cell lines, whereby...
In the paper, effect of voltage increasing (from 500 VDC up to 650 VDC) on structure and chemical composition porous coating titanium made by Plasma Electrolytic Oxidation, is presented. present phosphates based coatings enriched with calcium, magnesium, zinc copper in electrolyte 1 L 85% concentrated H3PO4 additions Ca(NO3)2·4H2O, Mg(NO3)2∙6H2O, Zn(NO3)2∙6H2O, Cu(NO3)2∙3H2O, are described. The morphology, phase composition, evaluated using SEM, EDS, XRD, XPS, GDOES. Based all...
Abstract Plasma Electrolytic Oxidation (PEO) known also as Micro Arc (MAO) process is widely used to fabricate porous coatings on titanium and its alloys mainly in water- acid-based solutions different applications, e.g. biomaterials, catalysts, sensors. In the present paper, SEM, EDS, XPS results of obtained by PEO treatment electrolytes based concentrated phosphoric H 3 PO 4 acid with calcium nitrate tetrahydrate Ca(NO ) 2 ·4H O, or magnesium hexahydrate Mg(NO ·6H zinc Zn(NO O for minutes...
The article describes the synthesis of selective dual emissive intramolecular charge transfer (ICT) receptor for zinc ion in acetonitrile, exhibiting aggregation induced emission enhancement (AIEE) solid state.
An investigation of the interactions two novel and several known DBTAA–adenine conjugates with double-stranded DNA RNA has revealed DNA/RNA groove as dominant binding site, which is in contrast to majority previously studied DBTAA analogues (DNA/RNA intercalators). Only DBTAA–propyladenine molecular recognition AT-DNA by an ICD band pattern > 300 nm, whereas significant bands did not appear for other ds-DNA/RNA. A structure–activity relation series compounds showed that essential...
The present paper covers the possible ways to fabricate advanced porous coatings that are enriched in copper on a titanium substrate through Direct Current Plasma Electrolytic Oxidation (DC-PEO) with voltage control, electrolytes made of concentrated orthophosphoric acid addition copper(II) nitrate(V) trihydrate. In these studies, solutions containing from 0 650 g salt per 1 dm3 and anodic voltages 450 V up were used. obtained featuring variable porosity could be best defined by...
Coatings enriched with zinc and copper as well calcium or magnesium, fabricated on titanium substrate by Plasma Electrolytic Oxidation (PEO) under AC conditions (two cathodic voltages, i.e., -35 -135 V, anodic voltage of +400 V), were investigated. In all experiments, the electrolytes based concentrated orthophosphoric acid (85 wt%) zinc, copper, and/or magnesium nitrates. It was found that introduced in ranges 5.0-5.4 at% 5.6-6.5 at%, respectively, while amounts range 0.3-0.6 at%....