- Gut microbiota and health
- Probiotics and Fermented Foods
- Liver Disease Diagnosis and Treatment
- Diet, Metabolism, and Disease
- Diet and metabolism studies
- Genomics, phytochemicals, and oxidative stress
- Biosensors and Analytical Detection
- Helicobacter pylori-related gastroenterology studies
- Microencapsulation and Drying Processes
- Listeria monocytogenes in Food Safety
- Microbial Metabolites in Food Biotechnology
- Food composition and properties
- Enzyme Production and Characterization
- Nanocomposite Films for Food Packaging
- Proteins in Food Systems
- Dietary Effects on Health
- Plant Water Relations and Carbon Dynamics
- Curcumin's Biomedical Applications
- Salmonella and Campylobacter epidemiology
- Inflammatory Bowel Disease
- Fibroblast Growth Factor Research
- Bacterial biofilms and quorum sensing
- Clostridium difficile and Clostridium perfringens research
- Hemostasis and retained surgical items
- Anaerobic Digestion and Biogas Production
Nanjing University of Finance and Economics
2017-2025
Chinese Academy of Forestry
2024-2025
Nanjing Agricultural University
2020-2021
Jiangsu University
2011
This research assessed the anti-inflammatory and hepatoprotective properties of inosine associated mechanism. Inosine pretreatment significantly reduced secretion several inflammatory factors serum alanine transaminase (ALT) aspartate amino transferase (AST) levels in a dose-dependent manner compared with lipopolysaccharide (LPS) group. In LPS-treated mice, ALT malondialdehyde (MDA) concentration elevated antioxidant enzyme activity. Furthermore, altered relative abundance genera,...
Probiotics, as dietary supplements, transmit their major effects through the regulation of gut microbiota. According to a previous study, one possible mechanism Lactobacillus casei CCFM419 protection against diabetes may involve flora. To test this hypothesis, high fat and streptozotocin-induced C57BL/6J mice were fed L. at 108, 109, 1010 colony forming units (CFU). Compared untreated mice, 109 CFU attenuated several symptoms diabetes, including fasting blood glucose, postprandial glucose...
Globally, type 2 diabetes (T2DM) is on the rise. Maintaining a healthy diet crucial for both treating and preventing T2DM.As common vegetable in daily diet, broccoli has antioxidant, anti-inflammatory anticarcoma physiological activities. We developed mouse model of carried out systematic investigation to clarify function reducing T2DM symptoms controlling intestinal flora. The findings demonstrated that could successfully lower fasting blood glucose (FBG), lessen insulin resistance,...
Abstract Sulforaphane (SFN) which is abundant in broccoli florets, seeds, and sprouts has been reported to have beneficial effects on attenuating metabolic diseases, such as antiobesity, antidiabetes, antioxidative activities. However, the of SFN regulation type II diabetes through easing nonalcoholic fatty liver (NAFLD) repairing pancreas tissue are rarely reported. In this study, we found that administration with different dosages was able increase serum insulin level, enhance HOMA‐β...
Brown seaweed is rich in polysaccharides including sulfated and alginate, both of which provide health benefits to the host but whose differences have not received sufficient attention. In this study, alginate from Undaria pinnatifida (UPA) U. (UPSP) were isolated, their action was analyzed high fat diet-fed mice. UPA UPSP improved body composition, deposition tissues organs, lipid abnormality inflammatory response mice, compound (UPP: + UPSP) had a better effect on some physiological...
Inflammatory bowel disease (IBD), which significantly affects human health, has two primary presentations: Crohn’s and ulcerative colitis (UC). Highland barley is the most common food crop for Tibetans contains much more β-glucan than any other crop. (HBBG) can relieve gastrointestinal dysfunction promote intestines health. This study aimed to evaluate whether HBBG UC in mice. A mouse model of was established by adding 2% dextran sulfate sodium (DSS) drinking water 1 week. alleviated after...
This study aims to explore the hypoglycemic effect of lyophilized broccoli microgreens on type 2 diabetes (T2D) in mice. The experiment lasted 18 weeks, including 1 week adaptation (normal diet) and 17-week experimental period (high-fat diet). After ingestion microgreens, body weight glucose homeostasis were improved. Meanwhile, blood lipid status, antioxidant indexes, inflammatory factors level Moreover, insulin resistance pathological changes mice organs reversed. In addition, composition...
Summary In this study, in vitro digestion and fermentation of Flammulina velutipes ‐derived polysaccharides ( FVP ) were investigated. It was found that mainly consisted 48.45% glucose, 15.40% mannose, 14.60% xylose, 11.80% fucose 9.90% galactose. The ‐human saliva, simulated gastric small intestinal juices conditions did not break down the . Based on tests, modulated composition gut microbiota by elevating amounts Bifidobacteriaceae Bacteroidaceae reducing numbers genera Lachnospiraceae...
The most common complications of obesity are metabolic disorders such as nonalcoholic fatty liver disease (NAFLD), hyperglycemia, and low-grade inflammation. Sulforaphane (SFN) is a hydrolysate glucosinolate (GLS) that found in large quantities cruciferous vegetables. objective this research was to evaluate the mechanism by which SFN relieves obese mice. C57BL/6J mice were fed high-fat diet induce treated daily with 10 mg/(kg body weight (bw)) for 8 weeks, while positive control group 300...
Trunk sap flow is essential for assessing plant water use efficiency and adaptation, yet the mechanisms underlying drought resistance utilization strategies in dry hot valleys remain poorly understood. This study investigates dynamics of four tree species (Albizia kalkora, Diospyros dumetorum, Terminalia franchetii, Acacia auriculiformis) a valley using Granier’s thermal diffusion probe method. The aims were to analyze interspecific differences their response environmental factors fitted...
Listeria monocytogenes biofilms represent a continuous source of contamination, leading to serious food safety concerns and economic losses. This study aims develop novel nisin-loaded chitosan nanoparticles (CSNPs) functionalized with DNase I evaluate its antibiofilm activity against L. on contact surfaces. Nisin-loaded CSNPs (CS-N) were first prepared by ionic cross-linking, was covalently grafted the surface (DNase-CS-N). The NPs subsequently characterized Zetasizer Nano, transmission...