A5014205800- Fermentation and Sensory Analysis
- Fungal and yeast genetics research
- Plant Gene Expression Analysis
- Plant and Fungal Interactions Research
- Antimicrobial Peptides and Activities
- RNA Research and Splicing
- Infectious Diseases and Mycology
- Veterinary Oncology Research
- RNA and protein synthesis mechanisms
- Cancer-related molecular mechanisms research
- Glycosylation and Glycoproteins Research
- Biochemical and Structural Characterization
Universidade Estadual Paulista (Unesp)
2021-2024
Universidade Federal de Juiz de Fora
2020
Ethanol (EtOH) alters many cellular processes in yeast. An integrated view of different EtOH-tolerant phenotypes and their long noncoding RNAs (lncRNAs) is not yet available. Here, large-scale data integration showed the core EtOH-responsive pathways, lncRNAs, triggers higher (HT) lower (LT) phenotypes. LncRNAs act a strain-specific manner EtOH stress response. Network omics analyses revealed that cells prepare for relief by favoring activation life-essential systems. Therefore, longevity,...
Antimicrobial resistance is considered a health issue worldwide. This public problem underscores the importance of searching for new antimicrobial molecules with different mechanisms action. Leaf transcriptomes were used to search and develop synthetic peptides derived from mRNA sequences. The in silico AMPs L. rotundifolia alba allowed identification 120 putative peptide Eight them fitted into optimal parameters translated chemically synthesized peptides. Their biological activity was...
Abstract The ethanol disturbs the cell cycle, transcription, translation, protein folding, wall, membranes, and many Saccharomyces cerevisiae metabolic processes. Long non-coding RNAs (lncRNAs) are regulatory molecules binding onto genome or proteins. number of lncRNAs described for yeast is still scarce, little known concerning their roles in system. There a lack knowledge how responsive to tolerance whether they act this tolerance. Hence, by using RNA-Seq data from S. strains with...
Abstract Ethanol (EtOH) is a substantial stressor for Saccharomyces cerevisiae . Data integration from strains with different phenotypes, including EtOH stress-responsive lncRNAs, are still not available. We covered these issues seeking systems modifications that drive the divergences between higher (HT) and lower (LT) tolerant under their highest stress conditions. showed phenotypes neither related to high viability nor faster population rebound after relief. LncRNAs work on many in...
Abstract Canine mammary cancer (CMCs) are common in female dogs and the main cause of animal deaths by cancer. Since immune system is an active player breast cancer, our goal was to better understand repertoires associated with dog patients. Therefore, we generated a dataset expressed immunoglobulin VH Vλ from hyperplastic tumoral tissues using Illumina genomic sequencing. Our results showed modulation tumors lesions. A consisting 18,000 unique sequences gene segments encoding variable...