Marcelo de Oliveira Santos

ORCID: 0000-0003-4909-2252
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About
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Research Areas
  • Plant tissue culture and regeneration
  • Biochemical and Structural Characterization
  • Transgenic Plants and Applications
  • Antimicrobial Peptides and Activities
  • Chromosomal and Genetic Variations
  • Essential Oils and Antimicrobial Activity
  • Plant biochemistry and biosynthesis
  • Neurofibromatosis and Schwannoma Cases
  • Mesenchymal stem cell research
  • Sarcoma Diagnosis and Treatment
  • Plant Reproductive Biology
  • Insect Resistance and Genetics
  • Tissue Engineering and Regenerative Medicine
  • Plant Stress Responses and Tolerance
  • Myeloproliferative Neoplasms: Diagnosis and Treatment
  • Sesquiterpenes and Asteraceae Studies
  • Plant-Microbe Interactions and Immunity
  • Pineapple and bromelain studies
  • Bone Tissue Engineering Materials
  • Plant responses to elevated CO2
  • Hemodynamic Monitoring and Therapy
  • Phytochemistry and Biological Activities
  • Kruppel-like factors research
  • Methemoglobinemia and Tumor Lysis Syndrome
  • Traditional and Medicinal Uses of Annonaceae

Universidade Federal de Juiz de Fora
2013-2023

Weatherford College
2022

Centro Científico Tecnológico - Tucumán
2022

Universidade de Brasília
2004-2008

Brazilian Agricultural Research Corporation
2008

Hospital Samaritano de São Paulo
1997

Antimicrobial peptides (AMPs) are compounds that act in a wide range of physiological defensive mechanisms developed to counteract bacteria, fungi, parasites and viruses. These molecules have become increasingly important as consequence remarkable microorganism resistance common antibiotics. This report shows Escherichia coli expressing the recombinant antimicrobial peptide Pg-AMP1 previously isolated from Psidium guajava seeds. The deduced open reading frame consists 168 bp long plus...

10.1016/j.peptides.2012.07.017 article EN publisher-specific-oa Peptides 2012-07-27

The Somatic embryogenesis receptor-like kinase (SERK) gene plays an important role in plant somatic and zygotic induction. encodes LRR-containing protein. Studies have been carried out focusing on different aspects of its function, but definitive conclusions are far from being reached. SERK expression is generally detected cells which or has triggered. Transgenic lettuce lines were produced to silence the endogenous using antisense RNA. average number seeds per flower R(1) R(2) generations...

10.1111/j.1438-8677.2008.00103.x article EN Plant Biology 2008-08-14

Nanomaterials can mimic properties of extracellular matrix molecules, promising great potential for scaffold composition in tissue engineering. In the present study, we investigated whether barium titanate nanoparticles (BT NP) combined with alginate polymer would provide a new cytocompatible three-dimensional (3D) to induce osteogenic stem cell differentiation. vitro cytocompatibility and differentiation were using human mesenchymal cells (MSC). Firstly, studied viability oxidative stress...

10.1088/1748-605x/ab0a52 article EN Biomedical Materials 2019-02-25

The aim of this work was to analyze terpene oil production and synthases (TPS) gene expression from leaves at different developmental stages chemotypes Lippia alba (Mill.) N.E. Br. ex Britton & P. Wilson, Verbenaceae. Hydro-distilled essential were used for chemical analysis three monoterpene synthase genes called LaTPS12, LaTPS23 LaTPS25 analyses associated production. putative TPS-b class. Semi-quantitative PCR quantitative (qPCR) investigate the profile those in leaf chemotypes....

10.1590/s0102-695x2012005000013 article EN cc-by-nc-nd Revista Brasileira de Farmacognosia 2012-01-14

Human accidents with venomous snakes represent an overwhelming public health problem, mainly in rural populations of underdeveloped countries. Their high incidence and the severity result 81,000 to 138,000 deaths per year. The treatment is based on administration purified antibodies, produced by hyper immunization animals generate immunoglobulins (Igs), then obtained fractionating immune plasma. use recombinant antibodies alternative conventional snakebite envenoming, particularly Fv...

10.1016/j.toxicon.2019.02.011 article EN publisher-specific-oa Toxicon 2019-02-22

Antimicrobial resistance is considered a health issue worldwide. This public problem underscores the importance of searching for new antimicrobial molecules with different mechanisms action. Leaf transcriptomes were used to search and develop synthetic peptides derived from mRNA sequences. The in silico AMPs L. rotundifolia alba allowed identification 120 putative peptide Eight them fitted into optimal parameters translated chemically synthesized peptides. Their biological activity was...

10.1016/j.peptides.2020.170317 article EN publisher-specific-oa Peptides 2020-04-22

By western blots, cross-immunoreactivity with polyclonal anti-potato apyrase antibodies identified the Calliandra brevipes as a band of 75 kDa in tissues non-galled stem and leaves, those globose galls. The hydrolysed either ATP, ADP, UDP, GTP or GDP. In galls, UDP GDP hydrolysis were 1.7–5.1-fold higher than tissues. ADP from gall 10–38% stimulated by 5 mM calcium, drastically reduced (66–99%) addition EDTA EGTA, confirming divalent cation dependence. Nucleotidase, phosphatase ATPase...

10.1071/bt12096 article EN Australian Journal of Botany 2012-01-01

Os objetivos deste trabalho foram estabelecer um protocolo eficiente de embriogênese somática, em híbridos triploides entre capim elefante (Pennisetum purpureum Schumach.) e milheto (P. glaucum (L.) R. Br.), avaliar por citometria fluxo a estabilidade genômica das plantas obtidas in vitro. A somática regeneração estabelecidas partir embriões zigóticos maduros milheto. Foram testados quatro tratamentos com 2,4 ácido diclorofenoxiacético (2,4 D), nas concentrações 0, 1, 2 3 mg L-1, para...

10.1590/s0100-204x2009000100006 article PT cc-by Pesquisa Agropecuária Brasileira 2009-01-01
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