Andrew Brazier

ORCID: 0000-0001-7260-3474
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About
Contact & Profiles
Research Areas
  • Cardiac Valve Diseases and Treatments
  • Aortic Disease and Treatment Approaches
  • Cardiac and Coronary Surgery Techniques
  • Infective Endocarditis Diagnosis and Management
  • Cardiovascular Issues in Pregnancy
  • Cardiac Structural Anomalies and Repair
  • Cardiac Arrest and Resuscitation
  • Aortic aneurysm repair treatments
  • Traumatic Brain Injury and Neurovascular Disturbances
  • Bariatric Surgery and Outcomes
  • Trauma Management and Diagnosis
  • Esophageal Cancer Research and Treatment
  • Trypanosoma species research and implications
  • Intestinal and Peritoneal Adhesions
  • Pleural and Pulmonary Diseases
  • Blood donation and transfusion practices
  • Mechanical Circulatory Support Devices
  • Airway Management and Intubation Techniques
  • Scientific Computing and Data Management
  • Lysosomal Storage Disorders Research
  • Cardiac tumors and thrombi
  • Congenital Diaphragmatic Hernia Studies
  • Pulmonary Hypertension Research and Treatments
  • Trauma, Hemostasis, Coagulopathy, Resuscitation
  • Organ Donation and Transplantation

Royal Stoke University Hospital
2023

Wythenshawe Hospital
2018-2021

National Health Service
2021

University Hospital Coventry
2020

Manchester University NHS Foundation Trust
2018-2019

Manchester Royal Infirmary
2015-2017

University of Manchester
2015

NHS Blood and Transplant
2014

Addenbrooke's Hospital
2012

Royal Albert Edward Infirmary
2011

In this White Paper, we present recommendations for the scientific community and funding agencies to foster infrastructure a collaborative multi-messenger time-domain astronomy (MMA/TDA) ecosystem. MMA/TDA is poised breakthrough discoveries in coming decade. much same way that expanding beyond optical bandpass revealed entirely new unexpected discoveries, cosmic messengers light (i.e., gravitational waves, neutrinos, rays) open windows answer some of most fundamental questions...

10.48550/arxiv.2401.02063 preprint EN other-oa arXiv (Cornell University) 2024-01-01

Hurler-Scheie syndrome is a rare lysosomal storage disease affecting the cardiovascular system. Besides cardiac manifestations, it presents with complications from abnormal proteoglycan deposition in soft tissues many locations, resulting joint contractures, paraplegia, impaired vision, airway narrowing and restrictive lung function, to name few. There are very few reports of surgical management valvular heart due mucopolysaccharidosis (MPS). We describe successful patient an extremely...

10.1136/bcr-2015-211551 article EN BMJ Case Reports 2015-11-05

Introduction Patients with complex coronary artery disease and severe aortic stenosis unsuitable for conventional cardiac surgery pose a significant treatment challenge. This is especially difficult patients where percutaneous revascularization technically very challenging and/or would not offer as complete revascularisation compared to surgical revascularisation. In addition, who are transfemoral transcatheter valve implantation (TAVI) an additional technical challenge, particularly dual...

10.1002/ccd.26610 article EN Catheterization and Cardiovascular Interventions 2016-07-12

Objective The coronavirus disease 2019 (COVID-19) pandemic has restructured the healthcare systems, prioritizing resources to treat COVID-19 patients. aim of this study was establish if patients affected by acute aortic syndrome (AAS) had unrestricted access emergency treatment and evaluate outcome these during peak pandemic. Methods This is a retrospective analysis prospectively collected data between March June 2020 from 19 participating cardiac surgery centers in United Kingdom. Results...

10.1111/jocs.15187 article EN cc-by Journal of Cardiac Surgery 2020-11-10

Extracorporeal membrane oxygenation is a safe modality of cardiorespiratory support for lung transplantation, with reduction in coagulopathy and transfusion requirement when compared cardiopulmonary bypass. In some scenarios, there are advantages to the use bypass, which allows cardiac decompression, filtering embolic air, easy addition removal volume, means immediately reintroduce lost blood into circulation. We describe novel circuit switch between modalities without prolonged interruption...

10.1177/0267659119868664 article EN Perfusion 2019-09-04

Abstract Background Surgical resection is the gold standard treatment for management of early-stage lung cancer. Several modifiable factors may significantly influence postoperative morbidity and mortality. We examined outcomes patients following based upon preoperative smoking status to quantify impact on outcomes. Methods Data from consecutive resections January 1, 2012 June 11, 2021 were included. Biopsies interstitial disease emphysematous or bullae excluded. Patients divided into three...

10.1055/a-2160-5091 article EN The Thoracic and Cardiovascular Surgeon 2023-08-25

Abstract Management of acute Type A aortic dissection can be complicated by patient comorbidities. We describe the case a 29-year-old female with preexisting peripartum cardiomyopathy who developed dissection. Surgery was performed and venoarterial extracorporeal membrane oxygenation (ECMO) instituted. She left hospital on 71st postoperative day. It is extremely rare for to develop an Deferring this patient's surgery ECMO center crucial her survival.

10.1055/s-0041-1736672 article EN cc-by Aorta 2021-02-01

U.K. blood component labels have evolved to accommodate a plethora of information. Concern has, however, been expressed that current labelling is too 'cluttered', detracting from the clarity critical This prompted holistic review and available information technology (IT) with aim improving situation.A survey was circulated requiring hospital participants rank each item on label according its 'criticality' assess three novel 'future' one 'transition' prototype labels. Prototypes were based...

10.1111/tme.12098 article EN Transfusion Medicine 2014-01-11

Hybrid surgical approaches are gaining popularity. Minimally invasive aortic valve replacement and percutaneous coronary intervention [PCI] is well documented. We wanted to explore the feasibility of trans-catheter implantation [TAVI] off pump artery bypass grafts [OPCAB].

10.1186/1749-8090-10-s1-a24 article EN cc-by Journal of Cardiothoracic Surgery 2015-12-01

Obesity is a major problem with the number of obese patients presenting to cardiac surgery ever increasing. Laparoscopic Adjustable Gastric Banding (LAGB) one modality commonly used mechanically reduce food intake and also promotes early satiety. Late complications device may occur in up 20% cases; increasing 30% pregnancy. We report first case late complication LAGB after cardiopulmonary bypass.

10.1186/1749-8090-10-s1-a170 article EN cc-by Journal of Cardiothoracic Surgery 2015-12-01

Transcatheter aortic valve implantation is at present reserved for patients with severe stenosis who are high risk conventional surgery or surgical access difficult due to heavily calcified aorta (porcelain aorta). However the calcium spikes root could pose a problem during balloon valvuloplasty resulting in rupture of balloon.

10.1186/1749-8090-10-s1-a316 article EN cc-by Journal of Cardiothoracic Surgery 2015-12-01

10.1016/j.ijsu.2017.08.126 article EN publisher-specific-oa International Journal of Surgery 2017-11-01

A 47-year-old patient was injured in a bomb blast and sustained trauma due to multiple fragments of shrapnel from terrorist explosive device. We report on the surgery required safely remove piece anterior wall main pulmonary artery (PA). chest X-ray revealed left-sided haemothorax. computed tomography scan confirmed trajectory position metal bolt that had lodged between PA aortic arch. At surgery, limited left thoracotomy performed initially. significant quantity blood observed pericardium,...

10.1093/ejcts/ezy326 article EN European Journal of Cardio-Thoracic Surgery 2018-09-24
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