A5079038543- Mechanical Circulatory Support Devices
- Cardiac Structural Anomalies and Repair
- Transplantation: Methods and Outcomes
- Cardiac, Anesthesia and Surgical Outcomes
- Cardiac and Coronary Surgery Techniques
- Cardiac Arrest and Resuscitation
- Organ Transplantation Techniques and Outcomes
- Aortic Disease and Treatment Approaches
- Aortic aneurysm repair treatments
- Cardiac Valve Diseases and Treatments
- Tracheal and airway disorders
- Renal Transplantation Outcomes and Treatments
- Hemostasis and retained surgical items
- Medical Imaging and Pathology Studies
- Surgical Simulation and Training
- SARS-CoV-2 and COVID-19 Research
- Immune Response and Inflammation
- Traumatic Brain Injury and Neurovascular Disturbances
- Infective Endocarditis Diagnosis and Management
- Lung Cancer Diagnosis and Treatment
- Pancreatitis Pathology and Treatment
- Sepsis Diagnosis and Treatment
- Airway Management and Intubation Techniques
- Surgical Sutures and Adhesives
- Trauma Management and Diagnosis
Wythenshawe Hospital
2005-2021
Manchester University NHS Foundation Trust
2015-2021
National Health Service
2021
University of Manchester
2005-2020
Saxon Academy of Sciences and Humanities in Leipzig
2019
Middlemore Hospital
2017
St Vincent's Hospital Sydney
2016
Manchester Academic Health Science Centre
2015
St James's University Hospital
2014
Central University Hospital of Asturias
2013
Objectives Social deprivation impacts on healthcare outcomes but is not included in the majority of cardiac surgery risk prediction models. The objective was to investigate geographical variations social patients undergoing and identify whether an independent predictor outcomes. Methods National Adult Cardiac Surgery Audit data for coronary artery bypass graft (CABG), or valve performed England between April 2003 March 2013, were analysed. Base hospitals divided into regions. measured by...
Surgical knots on the suture line provide an anchoring function, but also represent a potential source of infection and irritation donor leg after coronary artery bypass surgery. Knotless barbed sutures were designed to prevent knot-related complications. This study compared wound complication rates between patients receiving traditional monofilament those knotless for closure leg. One hundred forty-two randomized into two groups. Group 1 (n = 70) received 2 72) sutures. All wounds assessed...
Saphenous vein remains the most common conduit for coronary artery bypass grafting with increasing uptake of minimally invasive harvesting techniques. While Endoscopic Vein Harvest (EVH) has been demonstrated to improve early morbidity compared Open (OVH), recent literature suggests that this may be at expense graft patency one year and survival three years.We undertook a retrospective single-centre, single-surgeon, case-control study EVH (n = 89) OVH 182). The primary endpoint was death...
Trichosporon species are emerging opportunistic yeasts that cause life-threatening disseminated disease in severely immunocompromised patients. japonicum is a very rare of invasive trichosporonosis. We describe case fungemia an immunocompetent patient with transcutaneous biventricular assist device.
The National Institute for Health and Clinical Excellence (NICE) has produced new guidance in relation to the endoscopic harvesting of saphenous veins coronary artery bypass graft (CABG) surgery, advising that this procedure should only be used with special arrangements clinical governance, consent audit or research.1 NICE have been moved make these recommendations light recent evidence cast a shadow over vein patency patients who had venous conduit dissected by technique.2 paper question is...
Levels of the proinflammatory cytokine interleukin 6 (IL-6) increase after surgery. The functional polymorphism in IL-6 promoter region, G-174C, is associated with an increased risk coronary heart disease. We investigated genetic predisposition response to revascularization and studied association between G-174C polymorphism, levels, clinical outcomes surgery.DNA was obtained from 96 consecutive patients who underwent elective revascularization. Patients were genotyped for by means...
Variations in the expression and activity levels of multidrug-resistance MDR1/ABCB1 encoded P- glycoprotein (P-gp) have an impact on therapeutic efficacy many drugs. C3435T G2677 polymorphisms gene correlate with cellular P-gp, a membrane-bound efflux pump which removes multitude drugs, including chemotherapy drugs immunosuppressants, from cells. We aimed to investigate whether phenomenon drug resistance, mediated by seen tumor cells chemotherapeutic agents, is important field...
Figure 1 : Congenital complete absence of the pericardium. (A) Characteristic posteroanterior radiograph patient with congenital Note marked levoposition cardiac silhouette, loss right heart border, prominent main pulmonary artery, flattening and elongation left border (snoopy sign) lung tissue interposing between artery aorta (arrow). (B) Chest CT mediastinal setting shows characteristic interposition (arrow) (AO) (PA). (C) coronal sign). (D) axial showing leftward posterior rotation...
A best evidence topic in cardiothoracic surgery was written according to a structured protocol. The question addressed whether there is any survival benefit the employment of technique radical lymph node dissection management operable non-small cell lung cancer (NSCLC). Altogether 305 papers were found using reported search, which eight presented answer clinical question. author, journal, date and country publication, patient group studied, study type, relevant outcomes, results, weaknesses...
Only a small number of English hospitals provide postcardiotomy venoarterial extracorporeal membrane oxygenation (VA-ECMO) and there are doubts about its efficacy safety. The aim this service evaluation was to determine local survival rates report on patient demographics. This retrospective prospectively recorded routine clinical data from tertiary cardiothoracic center in the United Kingdom offering services including cardiac thoracic surgery, heart lung transplantation, venovenous...
The increasing prevalence of heart failure coupled with the shortage donor hearts has lead to an ever-growing demand for mechanical devices that can augment or replace failing human heart. This article describes modalities used treat end-stage and how these fit into a cardiac replacement therapy programme.
Objective The aim of the study was to assess whether use carbon dioxide insufflation has any impact on integrity long saphenous vein comparing 2 types endoscopic harvesting and traditional open harvesting. Methods A total 301 patients were prospectively randomized into 3 groups. Group 1 control arm (n = 101), group closed tunnel (carbon dioxide) 100) (open harvesting) 100). Each assessed determine systemic level partial arterial dioxide, end-tidal pH. Three blood samples obtained at...
Extracorporeal membrane oxygenation is a safe modality of cardiorespiratory support for lung transplantation, with reduction in coagulopathy and transfusion requirement when compared cardiopulmonary bypass. In some scenarios, there are advantages to the use bypass, which allows cardiac decompression, filtering embolic air, easy addition removal volume, means immediately reintroduce lost blood into circulation. We describe novel circuit switch between modalities without prolonged interruption...
This textbook offers the reader a comprehensible and wellillustrated journey through evidence available for management of all most commonly encountered vascular patient conditions. From consultants, trainees nurse specialists to stroke specialists, cardiologists, anaesthetists diabetologists this book easily accessible review material issues that are faced every day in disease. The second edition has come along way from original with addition several new chapters, which include designation...