Buyun Xu

ORCID: 0000-0001-7261-7876
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About
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Research Areas
  • Atrial Fibrillation Management and Outcomes
  • Cardiac Arrhythmias and Treatments
  • Cardiac electrophysiology and arrhythmias
  • Coronary Interventions and Diagnostics
  • COVID-19 Clinical Research Studies
  • Cardiac pacing and defibrillation studies
  • COVID-19 and healthcare impacts
  • COVID-19 diagnosis using AI
  • Acute Myocardial Infarction Research
  • Cardiac Imaging and Diagnostics
  • Antiplatelet Therapy and Cardiovascular Diseases
  • Alzheimer's disease research and treatments
  • Chronic Kidney Disease and Diabetes
  • Long-Term Effects of COVID-19
  • Healthcare and Venom Research
  • Plant-based Medicinal Research
  • Traumatic Brain Injury and Neurovascular Disturbances
  • Heart Rate Variability and Autonomic Control
  • Angiogenesis and VEGF in Cancer
  • Takotsubo Cardiomyopathy and Associated Phenomena
  • Cardiovascular and Diving-Related Complications
  • Venous Thromboembolism Diagnosis and Management
  • Traditional Chinese Medicine Analysis
  • Acute Kidney Injury Research
  • Vitamin K Research Studies

Shaoxing People's Hospital
2016-2025

Shaoxing University
2025

Zhejiang University
2018-2024

Second Affiliated Hospital of Zhejiang University
2023

Weatherford College
2022

Creative Commons
2022

Loma Linda University
2020

Atrial fibrillation (AF) is the most common cardiac arrhythmia and a major cause of ischemic stroke. Between 91% 100% cardiogenic thrombi are in left atrial appendage (LAA), morphology LAA might be associated with formation thrombus (LAAT). This review provides detailed discussion LAA’s anatomy LAAT’s diagnosis. It focuses on analyzing role blood stasis, morphological abnormality, hypercoagulable states. Accurate evaluation can assist risk stratification patients AF. The commonly used...

10.22541/au.174040926.66196506/v1 preprint EN Authorea (Authorea) 2025-02-24

Background Left atrial appendage (LAA) morphology predicts stroke risk in patients with fibrillation. However, it is not precisely understood how LAA influences risk. The present study aimed to investigate the relationship between and local thrombogenesis‐related blood parameters LAA. Methods Results We enrolled 205 undergoing catheter ablation of prevalence chicken wing–, cactus‐, windsock‐, cauliflower‐type LAAs were 23.9%, 32.7%, 29.3%, 14.1%, respectively. Blood samples collected from...

10.1161/jaha.120.020406 article EN cc-by-nc-nd Journal of the American Heart Association 2021-06-05

Comparing the hemodynamic parameters of thrombus-positive and thrombus-negative patients in early stages disease (before thrombus formation occurs) can help predict atrial fibrillation-related thrombosis. However, most clinical images are existing thrombus, presence thrombi blurs outline appendage intima. Therefore, using left (LAA) epicardial geometry for analysis has become a last resort. This study compares differences modeling contour inner outer membranes LAA. The research results show...

10.1063/5.0172261 article EN Physics of Fluids 2023-11-01

Abstract Introduction A left common pulmonary vein (LCPV) is a anatomical variant in atrial fibrillation (AF) patients. Whether an LCPV influences outcomes of repeated radiofrequency catheter ablation (RFCA) for AF has not been elucidated. Methods From prospectively collected database, we enrolled 154 patients who received RFCA recurrent after the initial (56 ± 9 years, 72% paroxysmal AF, 32 with LCPV, and 122 typical left‐sided veins [PVs]). Median postprocedural follow‐up was 26 months....

10.1111/jce.13876 article EN Journal of Cardiovascular Electrophysiology 2019-02-15

Atrial fibrillation (AF) is an arrhythmia disease that can disrupt the movement of left atrium (LA), which will facilitate thromboembolism in LA and further exacerbate stroke risk. The atrial appendage (LAA) a vital site for thrombus formation. morphology LAA believed to have profound effect on thrombosis. However, due limitation observation monitoring methods, mechanism this still unrevealed. Virchow's triad theory thrombogenic mechanisms, stating endothelial injury, blood...

10.1063/5.0214185 article EN Physics of Fluids 2024-07-01

Background: No previous studies exist investigating the optimal intensity of uninterrupted anticoagulation with warfarin during radiofrequency catheter ablation (RFCA) for atrial fibrillation (AF) in elderly. Objective: Evaluate efficacy and safety continuous low-intensity therapy throughout periprocedural period RFCA AF Methods: This is a prospective randomized study. We enrolled patients (age ≥ 70 years) who underwent first-time AF. Enrolled were to group A B. The international normalized...

10.1177/1060028017712532 article EN Annals of Pharmacotherapy 2017-06-02

This study aimed to investigate the effect of Xuefu Zhuyu decoction on preventing contrast-induced nephropathy (CIN) after percutaneous coronary intervention (PCI).A total 256 patients undergoing selective PCI for artery disease were consecutively enrolled and randomly divided into two groups: Group A (n = 126) B 130). Before PCI, all routinely received antiplatelet aggregation therapy, antilipidemic hydration therapy. Besides routine in from 3 days before PCI. Serum creatinine (Scr),...

10.1155/2020/5419016 article EN cc-by Evidence-based Complementary and Alternative Medicine 2020-01-01

The clinical treatment of coronary microvascular dysfunction (CMD) is mainly based on conventional medicine, but the mechanism medicine single and efficacy different. Shenmai injection (SMI) has a variety ingredients, effect SMI CMD not been studied. This study investigated its possible mechanism.The protective was evaluated in Sprague-Dawley (SD) rats human umbilical vein endothelial cells (HUVECs). In vivo, forty-five male SD were randomly divided into control group (sham group), (model...

10.1155/2022/8630480 article EN Evidence-based Complementary and Alternative Medicine 2022-06-09

Abstract In atrial fibrillation (AF) patients, complex electrograms during sinus rhythm (C-EGMs) could be pathological or not. We aimed to demonstrate whether local pacing was helpful discern C-EGMs. 126 persistent AF patients and 27 with left-side accessory pathway (LAP) underwent left mapping rhythm. If C-EGMs were detected, performed. the turned normal, we defined them as non-fixed C-EGMs, otherwise fixed No difference detected in incidence proportion of between LAP (101/126 vs. 19/27, P...

10.1038/s41598-022-14824-4 article EN cc-by Scientific Reports 2022-06-23

Uninterrupted warfarin during cryoballoon ablation (CB-A) of atrial fibrillation (AF) has been widely accepted. However, to our knowledge, no previous studies exist investigating the optimal intensity anticoagulation with for CB-A. This study aimed evaluate efficacy and safety uninterrupted low-intensity CB-A AF in elderly.Paroxysmal patients (age ≥ 70 years) who underwent were enrolled prospectively. The participants stratified into 2 groups based on international normalized ratio (INR)...

10.1111/jcpt.12671 article EN Journal of Clinical Pharmacy and Therapeutics 2018-02-26

This study investigates the efficacy and mechanisms of Kuanxiong Aerosol (KXA) on coronary microvascular dysfunction (CMD) in rats. Thirty-two Sprague-Dawley rats were divided into control, model, KXA, nicorandil groups, receiving respective treatments for three weeks. The CMD model was established byinjecting lauric acid left ventricle. Compared to group, KXA group showed significant reductions serum CK-MB, LDH, cTnI, ET-1, TNF-α, IL-6, MDA, ROS (p<0.01) increased NO SOD levels...

10.37360/blacpma.25.24.1.4 article EN Boletin Latinoamericano y del Caribe de plantas Medicinales y Aromaticas 2024-09-30

Background: Catheter ablation (CA) is a potentially curative method for treatment of severe symptomatic and drug-refractory atrial fibrillation (AF). Objectives: This study aimed to evaluate the impact steerable sheaths on catheter stability in paroxysmal AF based contact force (CF). Methods: Fifty-two patients were included this they randomly enrolled two groups: Pulmonary vein isolation using (Group 1, n=26) or fixed-curve 2, employing force-sensing catheter. We analyzed operator-blinded...

10.32592/ircmj.2022.24.4.1732 article EN cc-by-nc Iranian Red Crescent Medical Journal 2022-01-28
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