Chengchen Zhao

ORCID: 0000-0003-1118-5752
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About
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Research Areas
  • Cardiovascular Function and Risk Factors
  • Cardiac Imaging and Diagnostics
  • Heart Failure Treatment and Management
  • Atrial Fibrillation Management and Outcomes
  • Cardiac Valve Diseases and Treatments
  • Congenital Heart Disease Studies
  • ECG Monitoring and Analysis
  • Glioma Diagnosis and Treatment
  • Cardiovascular Disease and Adiposity
  • Hemoglobinopathies and Related Disorders
  • Radiomics and Machine Learning in Medical Imaging
  • Polyomavirus and related diseases
  • Iron Metabolism and Disorders
  • Acute Myeloid Leukemia Research
  • Cardiac Structural Anomalies and Repair
  • Erythropoietin and Anemia Treatment
  • Vascular anomalies and interventions
  • Nutrition and Health in Aging
  • Pulmonary Hypertension Research and Treatments
  • Fuel Cells and Related Materials
  • Viral-associated cancers and disorders
  • Retinoids in leukemia and cellular processes
  • Histiocytic Disorders and Treatments
  • Hyperglycemia and glycemic control in critically ill and hospitalized patients
  • Advanced MRI Techniques and Applications

Zhejiang University
2022-2025

Second Affiliated Hospital of Zhejiang University
2006-2024

Xiangya Hospital Central South University
2020

Central South University
2020

Background: Iron deficiency is common in cardiovascular diseases (CVD), e.g., heart failure and coronary disease. Soluble transferrin receptor (sTfR) a promising marker representing unmet cellular iron demands. However, whether higher serum sTfR associated with increased risk of CVDs needs further investigation. Methods: In the present cross-sectional study, we analyzed data 4,867 adult participants National Health Nutrition Examination Survey (NHANES) 2017-2018. Linear regression models...

10.3389/fcell.2022.874846 article EN cc-by Frontiers in Cell and Developmental Biology 2022-04-12

Background: Inflammation is essential in cardiorenal syndrome, however there still a lack of evidence proving the interaction between cardiac injury, renal dysfunction and inflammatory response. This study aimed to illustrate association injury with specific focus on role inflammation. Methods: A single-center, retrospective included patients heart failure admitted cardiovascular department from September 2019 April 2022. Patients received magnetic resonance (CMR) imaging (T1 mapping late...

10.31083/j.rcm2504148 article EN cc-by Reviews in Cardiovascular Medicine 2024-04-22

Background: Perturbation of energy metabolism exacerbates cardiac dysfunction, serving as a potential therapeutic target in congestive heart failure. Although circulating free fatty acids (FFAs) are linked to insulin resistance and risk coronary disease, it still remains unclear whether FFAs associated with the prognosis patients acute failure (AHF). Methods: This single-center, observational cohort study enrolled 183 AHF (de novo or decompensated chronic failure) Second Affiliated Hospital,...

10.3389/fcvm.2021.761537 article EN cc-by Frontiers in Cardiovascular Medicine 2021-12-22

Abstract Rationale: Interdigitating dendritic cell sarcoma (IDCS) is an extremely rare disease originating from cells (DCs). There are few cases report interdigitating of spleen along with their pathological characteristics and treatment. Patient concerns: Here we a case IDCS in 53-year-old female who presented enlargement thrombocytopenia. Diagnoses: The patient underwent surgical resection spleen, the pathology confirmed IDCS. Interventions: She received one cycle chemotherapy (ABVD...

10.1097/md.0000000000015535 article EN cc-by-nc Medicine 2019-05-01

ABSTRACT Aims/Introduction Diabetes mellitus is a traditional risk factor for heart failure (HF), and glycated albumin (GA) marker to assess short‐term glycemic control. Whether GA has prognostic significance in patients with HF remains unclear. Materials Methods A total of 717 were enrolled the prospective cohort study. Patients grouped by normal upper limit (17%). Kaplan–Meier analysis Cox proportional hazards regression used evaluate association between prognosis. Results During mean...

10.1111/jdi.14255 article EN cc-by-nc Journal of Diabetes Investigation 2024-07-05

CMR multitasking T1 mapping, a recently proposed free-breathing, non-ECG technique, was evaluated in atrial fibrillation patients. It demonstrated good image quality, differentiated patients from healthy participants, and correlated with important cardiac function biomarkers. is promising mapping tool

10.58530/2023/4858 article EN Proceedings on CD-ROM - International Society for Magnetic Resonance in Medicine. Scientific Meeting and Exhibition/Proceedings of the International Society for Magnetic Resonance in Medicine, Scientific Meeting and Exhibition 2024-08-14

Cardiovascular diseases (CVDs) present significant challenges for early and accurate diagnosis. While cardiac magnetic resonance imaging (CMR) is the gold standard assessing function diagnosing CVDs, its high cost technical complexity limit accessibility. In contrast, electrocardiography (ECG) offers promise large-scale screening. This study introduces CardiacNets, an innovative model that enhances ECG analysis by leveraging diagnostic strengths of CMR through cross-modal contrastive...

10.48550/arxiv.2411.13602 preprint EN arXiv (Cornell University) 2024-11-19

Background: Mitral regurgitation (MR) has a high prevalence and aggravates hypoperfusion hypoxia in heart failure (HF). Renal tubular epithelial cells are sensitive to hypoxia, therefore tubulointerstitial damage is quite common HF. However, the correlation between dysfunction MR not been studied. The aim of this work was evaluate prognostic significance urinary N-acetyl-β-d-glucosaminidase (uNAG), biomarker renal damage, patients with HF MR. Methods: This prospective cohort study 390 (mean...

10.31083/j.rcm2408219 article EN cc-by Reviews in Cardiovascular Medicine 2023-07-31

In the clinical settings, disseminated intravascular coagulation (DIC) and complications such as hemorrhage are commonly seen in acute promyelocytic leukemia patients, whereas thrombosis is rarely reported. We reported a case here that patient presented with cerebral infarction first manifestation. During admission, encountered differentiation syndrome, pulmonary embolism, hemorrhage, myocardial ischemia, well bleeding complications. Hence was diagnosed DIC. After treatment of blood...

10.11817/j.issn.1672-7347.2020.190008 article EN PubMed 2020-04-28

A 50-year-old woman was admitted to the coronary care unit due recurrent chest distress for 30 years. She successfully gave birth a healthy boy at age of 24. Physical examination showed pan systolic multifocal murmur, severe acropachia, and cyanosis (Panel A). Her oxygen saturation 76% room air. Both transthoracic echocardiography computed tomographic angiography suggested truncus arteriosus (Panels B C). Cardiovascular magnetic resonance illustrated large, persistent (PTA) arising from base...

10.1093/eurheartj/ehad183 article EN European Heart Journal 2023-03-29

1523 Background: The early prediction of glioma prognosis is very important. Amino acid metabolism associated with numerous catabolic processes favoring tumor growth. As an essential amino acid, L-methionine plays a central role in the altered cancer cells. aim this study was to evaluate prognostic value PET imaging using 11C-methionine (MET) patients gliomas treated by radiotherapy. Methods: MET prospectively performed 36 before and within one month after Tumor uptake measured...

10.1200/jco.2006.24.18_suppl.1523 article EN Journal of Clinical Oncology 2006-06-20

Abstract Purpose: Applicating cardiovascular magnetic resonance (CMR) 4D flow to evaluate left ventricular systolic and diastolic function in atrial fibrillation (AF). Methods: In this study, from May 2021 October 2021, 26 AF patients 15 healthy participants were recruited underwent multiparametric CMR echocardiogram scans before discharge. The protocol incorporated an assessment of flow, cardiac function. Notably, the maintained irregular heart rhythm during scan. components compared with...

10.21203/rs.3.rs-1307383/v1 preprint EN cc-by Research Square (Research Square) 2022-02-03
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