Alexander Duplooy

ORCID: 0000-0001-7274-5261
Publications
Citations
Views
---
Saved
---
About
Contact & Profiles
Research Areas
  • Caveolin-1 and cellular processes
  • Signaling Pathways in Disease
  • MicroRNA in disease regulation
  • Adipose Tissue and Metabolism
  • Memory and Neural Mechanisms
  • Oropharyngeal Anatomy and Pathologies
  • Shoulder Injury and Treatment
  • Shoulder and Clavicle Injuries
  • Spectroscopy Techniques in Biomedical and Chemical Research
  • Metabolomics and Mass Spectrometry Studies
  • Stress Responses and Cortisol
  • Neurogenesis and neuroplasticity mechanisms

Tulane University
2025

Louisiana State University
2022-2024

Oxidative and lipid homeostasis are altered by stress trauma post-traumatic disorder (PTSD) is associated with alterations to species in plasma. Stress-induced oxidative may exacerbate PTSD pathology, but few preclinical investigations of stress-induced lipidomic changes the brain exist. Currently available techniques for quantification biological samples require tissue extraction limited their ability retrieve spatial information. Raman imaging can overcome this limitation through

10.1016/j.ynstr.2022.100476 article EN cc-by-nc-nd Neurobiology of Stress 2022-08-11

Abstract Stress is associated with contextual memory deficits, which may mediate avoidance of trauma‐associated contexts in posttraumatic stress disorder. These deficits emerge from impaired pattern separation, the independent representation similar experiences by dentate gyrus‐Cornu Ammonis 3 (DG‐CA3) circuit dorsal hippocampus, allows for appropriate behavioral responses to specific environmental stimuli. Neurogenesis DG controlled mitochondrial reactive oxygen species (ROS) production,...

10.1111/gbb.12840 article EN cc-by-nc-nd Genes Brain & Behavior 2023-02-17

<title>Abstract</title> Caveolin-1 (Cav-1) is a critical lipid raft protein playing divergent roles as both tumor suppressor and promoter. While its role in tumorigenesis, progression, metastasis recognized, explicit contribution of Cav-1 to the onset lung from primary breast malignancies remained vague. We exhibit here, first-ever evidence knockout epithelial cells leading significant reduction syngeneic mouse models cancer. In vitro, 4T1 suppressed extracellular vesicles secretion,...

10.21203/rs.3.rs-3677189/v1 preprint EN cc-by Research Square (Research Square) 2023-12-12
Coming Soon ...