- Seaweed-derived Bioactive Compounds
- Bone Tissue Engineering Materials
- Nanoplatforms for cancer theranostics
- Polysaccharides and Plant Cell Walls
- Atmospheric aerosols and clouds
- Pharmacological Effects of Natural Compounds
- Thermal Radiation and Cooling Technologies
- Tissue Engineering and Regenerative Medicine
- Fluid Dynamics and Mixing
- Phytoestrogen effects and research
- Natural product bioactivities and synthesis
- Textile materials and evaluations
- Non-Destructive Testing Techniques
- Ultrasonics and Acoustic Wave Propagation
- Dental Implant Techniques and Outcomes
- Echinoderm biology and ecology
- Medicinal Plant Pharmacodynamics Research
- Phase Change Materials Research
- Titanium Alloys Microstructure and Properties
- Nanoparticles: synthesis and applications
- Wound Healing and Treatments
- Orthopedic Infections and Treatments
- Silk-based biomaterials and applications
- Polysaccharides Composition and Applications
- Electrochemical Analysis and Applications
Xi'an University of Technology
2025
Huaqiao University
2013-2024
Nanchang University
2017-2024
Guangdong University of Foreign Studies
2024
Bournemouth University
2024
Zhejiang Lab
2024
Second Affiliated Hospital of Nanchang University
2017-2023
First Affiliated Hospital of Nanchang University
2019-2023
Tianjin Hospital
2023
Jimei University
2022
Helicobacter pylori (H. pylori) infection is the leading cause of chronic gastritis, peptic ulcer, and gastric cancer. Antibiotics, as traditional method for eliminating H. pylori, have no targeting effect, which causes serious bacterial resistance gut dysbacteriosis. Moreover, antibiotics can hardly address hyperactive inflammatory response or damaged mucosal barrier caused by infection. Here, a pH-responsive metal-organic framework hydrogen-generation nanoparticle (Pd(H) @ ZIF-8) reported,...
Periodontitis is a bacterial infectious disease leading to the loss of periodontal supporting tissues and teeth. The current guided tissue regeneration (GTR) membranes for periodontitis treatments cannot effectively promote limited antibacterial properties excessively fast degradation rate. Besides, they need extra tailoring according variform defects before implantation, imprecise match. This study proposed an injectable sodium alginate hydrogel composite (CTP-SA) doped with cubic cuprous...
The development of green and sustainable extraction technologies for various naturally active biomaterials is gaining increasing attention due to their environmentally friendly advantages. In this work, the ultrasonic-assisted fucoxanthin from edible brown algae Sargassum fusiforme using different solvents was presented. Ethyl lactate, limonene, soybean oil, sunflower oil were used in place traditional organic solvents. lactate showed similar performance solvents, whereas limonene vegetable...
Osteoporosis is one of the most common diseases affecting bone metabolism. Nitric oxide (NO), an endogenous gas molecule involved in osteogenesis, can effectively promote proliferation and differentiation osteoblasts. Although exogenous NO reverse osteoporosis to a certain extent, transitory half-life short diffusion radius severely limit its application. In this work, generation nanoplatform with targeting property (UCPA) developed based on upconversion nanoparticles (UCNPs) that convert...
Background: Nowadays, zirconia ceramic implants are widely used as a kind of hip prosthesis material because their excellent biocompatibility and long-term wear resistance. However, the joint is one major joints with complex 3D morphological structure greatly individual differences, which usually causes great waste during process surgical selection prosthesis. Methods: In this paper, by combining printing technology antibacterial nano-modification, implant was obtained precise effective...
To endow Ti-based orthopedic implants with strong bactericidal activity, a ZnO nanorods-patterned coating (namely ZNR) was fabricated on Ti utilizing catalyst- and template-free method of micro-arc oxidation (MAO) hydrothermal treatment (HT). The comprises an outer layer nanorods partially crystallized inner nanocrystalline TiO2 Zn2TiO4 embedded amorphous matrix containing Ti, O Zn. During HT, Zn2+ ions contained in the as-MAOed migrate to surface react OH- solution form nuclei growing...
Inspired by cicadas and catkins, a delicate dual biomimetic antibacterial concept was proposed to modify implant material.
Addressing the issue of porosity evolution during curing process thermosetting epoxy resin-based composites, a simulation model has been developed to describe flow–compaction behavior composites aiming predict changes in throughout process. Initially, multi-physics coupling encompassing sub-models for thermo-chemical, fiber bed compression, void and percolation flow was established. This accurately describes within The UMAT subroutine ABAQUS finite element analysis software utilized...
The application of polydopamine (PDA)-modified titanium dioxide nanoparticles (nano-TiO2@PDA) as a new blue-light-activated tooth whitening material was discussed for the first time. Compared with classical clinical agent (peroxide, hydrogen peroxide, and carbamide peroxide), nano-TiO2@PDA-based treatment not only had similar effect but also showed remarkably less damage on enamel structure. Essentially, highly effective nondestructive could thus be realized accordingly. toxicity...
Type 2 diabetes mellitus (T2DM) accounts for more than 90% of cases mellitus, which is harmful to human health. Herein, neoagaro-oligosaccharides (NAOs) were prepared and their potential as a treatment T2DM was evaluated in KunMing (KM) mice. Specifically, mice model established by the combination high-fat diet (HFD) alloxan injection. Consequently, given different doses NAOs (100, 200, or 400 mg/kg) differences among groups recorded. As result treatment, fasting blood glucose (FBG) lowered...
Inspired from falling leaves, ZnO nanorods-nanoslices hierarchical structure (NHS) was constructed to modify the surfaces of two widely used implant materials: titanium (Ti) and tantalum (Ta), respectively. By which means, two-stage release antibacterial active substances were realized address clinical importance long-term broad-spectrum activity. At early stages (within 48 h), NHS exhibited a rapid releasing kill bacteria around immediately. second stage (over 2 weeks), slow realize...
Systemic thrombolytic drug administration has always gained an unideal therapeutic effect due to the rapid neutralization by its antidotes. It is significant seek approach for targeted delivery thrombus. Here a biocompatible, thrombus-targeted, and low-cost platelet-mimic nanovector was fabricated accomplish sustained urokinase plasminogen activator (uPA) release at thrombus site. The prepared system presented model behavior 30 h burst under near-infrared laser irradiation with hyperthermia...
Background: Osteoarthritis (OA) is degenerative joint disorder mainly characterized by long-term pain with limited activity of joints, the disease has no effective preventative therapy. Rutin (RUT) a flavonoid compound, present naturally. The shows range biological activities such as anti-inflammatory and anti-cancer effect. We screened RUT for its against osteoarthritis in vivo vitro models osteoarthritis. Methods: Animal model OA was developed using C57BL/6 mice surgical destabilization...
The most prevalent primary malignant tumor of CNS is glioma, which has a dismal prognosis. theory oxidative stress one the important theories in study its occurrence and development mechanism. In this study, impacts PCBP2 on glioma sufferers possible mechanisms were examined. Patients with obtained from May 2017 to July 2018. Quantitative PCR, microarray analysis, western blot immunofluorescence used experiment. mRNA expression level protein patients upregulated compared paracancerous...