A5002977111- Genetics, Aging, and Longevity in Model Organisms
- Probiotics and Fermented Foods
- Protein Hydrolysis and Bioactive Peptides
- Circadian rhythm and melatonin
- Biochemical Acid Research Studies
- Biochemical effects in animals
- Antimicrobial Peptides and Activities
- Phytochemicals and Antioxidant Activities
- Biochemical Analysis and Sensing Techniques
- Antenna Design and Analysis
- Bacillus and Francisella bacterial research
- Proteins in Food Systems
- Natural product bioactivities and synthesis
- Adipose Tissue and Metabolism
- Microwave Engineering and Waveguides
- Pharmacological Effects of Natural Compounds
- Genomics, phytochemicals, and oxidative stress
- Animal Nutrition and Physiology
- Bacteriophages and microbial interactions
- Food Chemistry and Fat Analysis
- Fungal Biology and Applications
- Seed and Plant Biochemistry
- Antioxidant Activity and Oxidative Stress
- Mitochondrial Function and Pathology
- Bioactive natural compounds
Minzu University of China
2022-2025
South China Agricultural University
2015-2025
Key Laboratory of Guangdong Province
2016-2024
Renmin University of China
2021-2022
State Council of the People's Republic of China
2017-2020
Rutgers, The State University of New Jersey
2014-2020
Nanjing University of Science and Technology
2016-2019
WuXi AppTec (China)
2019
China Agricultural University
2015
Yunnan University
2011-2012
The study offers methods and models for elucidating healthspan promotion mechanism, valuable studies of other naturally active compounds.
Polymethoxyflavones (PMFs) have been shown to prevent obesity, ameliorate type 2 diabetes, and regulate lipid metabolism in vitro vivo. However, little is known about the contribution of 3,5,6,7,8,3′,4′-heptamethoxyflavone (HMF) obesity We aimed investigate potential efficacy HMF on preventing hyperlipidemia rats fed a high-fat diet (HFD) its underlying mechanisms. Male Sprague–Dawley were normal or an HFD with without (0.02%, 0.04% 0.08%, w/w) for 6 weeks. The supplementation not only...
Tangeretin (TAN) exhibited antilipogenic, antidiabetic, and lipid-lowering effects. However, the lipid biomarkers underlying mechanisms for antiobesity cholesterol-lowering effects of TAN have not been sufficiently investigated. Herein, we integrated biochemical analysis with lipidomics to elucidate its efficacy in high-fat diet-fed rats. at supplementation levels 0.04 0.08% only significantly decreased body weight gain, serum total cholesterol, low-density lipoprotein cholesterol but also...
Rosmarinic acid (RA) has a wide range of biological effects, including the antioxidation and antiaging. However, detailed mechanisms remain unclear but highly attractive. Herein, RA promoted lifespan motoricity in dose-dependent manner, reduced fat store without threatening fertility Caenorhabditis elegans. In term antioxidant efficacy, catalase activity, glutathione peroxidas content, glutathione/oxidized ratio were enhanced. And malondialdehyde content was diminished significantly....
The multicellular model organism Caenorhabditis elegans (C. elegans) was used to identify the anti-aging effect of pentagalloyl glucose (PGG) isolated from Eucalyptus leaves at four different concentrations. For 160 μM PGG, median lifespan C. found increase by 18%, and thermal stress resistance also increased. PGG did not cause side effects on physiological functions including reproduction, pharyngeal pumping rate, age pigments accumulation, locomotion ability. life extension induced rely...
Carnosol, a phenolic diterpene, is one of the main constituents Rosmarinus . It known to possess range bioactivities, including antioxidant, anticancer, antimicrobial, and anti-inflammatory properties. Nevertheless, antiaging effects carnosol have received little attention. This study first indicated that increased healthspan Caenorhabditis elegans ( C. ). First, compared with control condition, treatment effectively decreased ROS accumulation under normal or oxidative stress significantly...
Ganoderma lucidum polysaccharides (GLP) exhibited excellent immunomodulatory activity. Unfortunately, the structure and activity of GLP are still unclear. was separated into two fractions [high Mw Restriction Fragment Length Polymorphism (RGLP) low EGLP] using 10 kDa cut-off ultrafiltration membrane. Although RGLP content in GLP, significantly higher than that EGLP. Moreover, further via Sephacryl column to obtain RGLP-1 showed best macrophage RAW264.7 model. Structural analysis revealed...
Objective Bacillus cereus ( B. ) can be used as a probiotic or produce variety of toxins that are pathogenic to humans and animals. Environmental stressors affect the growth process expression its virulence genes. Due limitations methods such pharmacological disinfection (there limits use antibiotics) chemical (chemical may residues), attempts made remove reduce infections through environmental stress factors. Methods In this study, four genes nheA , hblD cytK entFM bovine-origin lethal was...
The study offers methods and models for elucidating fat accumulation mechanisms, valuable studies of other plant-based nutraceuticals.
Lipid oxidation is still one of the major food-safety issues associated with emulsion-based food systems. Engineering interfacial region an effective way to improve oxidative stability emulsion. Herein, a novel Pickering emulsion strong was prepared by using zein nanoparticles and Tween 20 as stabilizers (ZPE). The modulation effects particle size on distribution gallic acid (GA) ZPE were investigated. In absence GA, emulsions stabilized different sizes showed similar stability, physical...
Oxyresveratrol could strongly inhibit tyrosinase activity and decrease melanin production<italic>in vitro</italic>and<italic>in vivo</italic>.