- Aquaculture disease management and microbiota
- Neuroblastoma Research and Treatments
- Identification and Quantification in Food
- Invertebrate Immune Response Mechanisms
- Bacillus and Francisella bacterial research
- Bacteriophages and microbial interactions
- Fish Biology and Ecology Studies
- Cancer, Hypoxia, and Metabolism
- Aquaculture Nutrition and Growth
- Cancer-related molecular mechanisms research
- interferon and immune responses
- Immune Cell Function and Interaction
- Animal Disease Management and Epidemiology
- Genomics and Phylogenetic Studies
- Antibiotic Resistance in Bacteria
- ATP Synthase and ATPases Research
- Fish Ecology and Management Studies
- Ultrasound Imaging and Elastography
- Vibrio bacteria research studies
- Renal and related cancers
- Hemophilia Treatment and Research
- Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
- Crustacean biology and ecology
- Animal Virus Infections Studies
- Animal Nutrition and Physiology
Minzu University of China
2023-2025
Shandong Freshwater Fisheries Research Institute
2012-2024
Yan'an University
2024
Henan Provincial People's Hospital
2015-2022
Zhengzhou University
2020
Shandong Entry-Exit Inspection and Quarantine Bureau
2016
Ocean University of China
2004-2013
First Affiliated Hospital of Zhengzhou University
2011
Hebei Normal University
2009
Objective Bacillus cereus ( B. ) can be used as a probiotic or produce variety of toxins that are pathogenic to humans and animals. Environmental stressors affect the growth process expression its virulence genes. Due limitations methods such pharmacological disinfection (there limits use antibiotics) chemical (chemical may residues), attempts made remove reduce infections through environmental stress factors. Methods In this study, four genes nheA , hblD cytK entFM bovine-origin lethal was...
MicroRNAs (miRNAs) play important roles in regulation of many biological processes eukaryotes, including pathogen infection and host interactions. Flavobacterium columnare (FC) can cause great economic loss common carp (Cyprinus carpio) which is one the most cultured fish world. However, miRNAs response to FC has not been characterized. To identify specific involved infected with FC, we performed microRNA sequencing using livers without FC. A total 698 were identified, 142 identified...
Albinism is a genetic disorder caused by series of abnormalities that result in decrease melanin. Golden yellow snakehead fish (GCAS) has been discovered while the Channa argus (CAS) breeding, but mechanism causes its albinism not known. Transcriptome sequencing and comparison CAS GCAS skin using Oxford Nanopore Technologies (ONT) technology to elucidate molecular mechanisms albinism.27.1 G clean reads 26,198 full-length non-redundant sequences were generated via ONT sequencing. Overall,...
Antibiotic-resistant bacteria are a serious threat to human and animal health. Metabolite-enabled eradication of drug-resistant pathogens is an attractive strategy, metabolite adjuvants, such as fumarate, used for restoring the bactericidal ability antibiotics. However, we show that metabolites in TCA cycle increase viability Edwardsiella tarda against chloramphenicol (CAP), based on survival assay differential identified by LC-MS/MS. Furthermore, NADPH promotes CAP resistance CAP-resistant...
The successful induction of triploid embryos or larvae has been performed in Patinopecten yessoensis during the past 2 decades. However, no research reported about performance P. cultured field. This study induced triploidy by hypotonic shock and compared growth reproductive triploids diploids reared under commercial conditions for up to 24 mo. main results this are as follows: Triploid scallops were smaller size weight with had a retarded absolute rate (AGR). After mo cultivation, mean...
Although cellular metabolic states have been shown to modulate bacterial susceptibility antibiotics, the interaction between glutamate (Glu) and chloramphenicol (CAP) resistance remains unclear because of specificity antibiotics bacteria. We found that level Glu was upregulated in CAP-resistant strain Edwardsiella tarda according a comparative metabolomics approach based on LC–MS/MS. Furthermore, we verified exogenous metabolites related Glu, tricarboxylic acid (TCA) cycle, glutathione (GSH)...
The immunoglobulins (Ig) and polymeric immunoglobulin receptor (pIgR) are crucial in protecting organisms against pathogen invasion. However, further clarification regarding their mucosal immune responses is required, particularly when considering various vaccine administration routes. Herein, polyclonal antibodies largemouth bass (Micropterus salmoides) recombinant pIgR IgM were prepared, respectively. Moreover, response features investigated after immunization via bath intraperitoneal...
Abstract The objective of this study was to estimate overall survival in children with extremity rhabdomyosarcoma (RMS). In addition, we attempted construct a nomogram predict the prognosis such patients using population-based cohort. national Surveillance, Epidemiology, and End Results (SEER) registry used identify cohort childhood RMS patients. A total 197 were ultimately included. Multivariable analysis identified age group, N classification, M treatment combinations as independent...
In order to identify the cause of death a cattle that suddenly died on farm in Tongliao City, Inner Mongolia Autonomous Region, we isolated strain bacteria from spleen and identified pathogen. The study demonstrated is Bacillus cereus. isolates were highly pathogenic contained toxin genes, such as hbl, nhe, entFM, addition groEL housekeeping gene. has been named TL (16S rDNA sequence number: OP028902, whole genome CP129005). Isolates deposited at China General Microbiological Culture...
The present study aimed to identify the genes directly or indirectly correlated with amplification of MYCN in neuroblastoma (NB). Microarray data (GSE53371) were downloaded from Gene Expression Omnibus, and included 10 NB cell lines normal copy numbers. Differentially expressed (DEGs) identified using Linear Models for Data package, a false discovery rate <0.05 |log2FC (fold change)|>1 selected as cut‑off criteria. Hierarchical clustering analysis Ontology respectively performed DEGs...
We sequenced and characterized the complete mitochondrial genome of golden yellow snakehead fish, Channa argus. The mitogenomes contained typical complement 13 protein-coding genes, 22 transfer RNAs (tRNAs), 2 ribosomal (rRNAs), a non-coding control region. They share same gene arrangement pattern that was identical with most vertebrates. entire DNA molecule fish 16,558 bp long. All information reported in this article will be useful source sequence for general molecular evolutionary studies...