A5023483280- Toxoplasma gondii Research Studies
- Herpesvirus Infections and Treatments
- Rabies epidemiology and control
- Parasitic Infections and Diagnostics
- Animal Disease Management and Epidemiology
- Yersinia bacterium, plague, ectoparasites research
- Mosquito-borne diseases and control
- Cytomegalovirus and herpesvirus research
- Sex work and related issues
- Travel-related health issues
- Pediatric health and respiratory diseases
- Insect and Pesticide Research
- Vector-borne infectious diseases
- Viral Infections and Vectors
- Genetic diversity and population structure
- Identification and Quantification in Food
Inserm
2019-2024
Institut d’Epidémiologie Neurologique et de Neurologie Tropicale
2017-2024
Institut de Recherche pour le Développement
2020-2024
Université de Limoges
2018-2024
Hôpital Universitaire Dupuytren
2024
Hôpital Dupuytren
2024
Institut d’Epidémiologie et de Neurologie Tropicale
2017-2023
Centre Hospitalier Universitaire de Limoges
2019
Abstract Toxoplasma gondii is a cyst-forming apicomplexan parasite of virtually all warm-blooded species, with true cats (Felidae) as definitive hosts. It the etiologic agent toxoplasmosis, disease causing substantial public health burden worldwide. Few intercontinental clonal lineages represent large majority isolates Little known about evolutionary forces driving success these lineages, timing and mechanisms their global dispersal. In this study, we analyse set 156 genomes provide...
Introduction There have only been a few molecular studies conducted on the detection of T. gondii in tissues carnivores South Africa, with no data genetic diversity this parasite. That is why aim study was to detect and genotype DNA selected wild domestic Africa. Methods Samples were collected from 80 animals 20 species (mainly road-killed) four provinces Limpopo (n=57), Mpumalanga (n=21), Gauteng (n=1) Free State during period 2014–2018. brain (n=31), heart (n=4), liver (n=40), spleen (n=2)...
Toxoplasma gondii is a zoonotic protozoan with worldwide occurrence, but the determinants of current pattern in geographical distribution T. lineages and strains remain poorly understood. To test influence human trade on populations, we conducted population genetic study 72 animal isolates from Senegal, West African country which ongoing inland progress invasive murine hosts (introduced port cities Senegal since 16th century by European sailors) well described. Isolates were mainly collected...
Through international trades, Europe, Africa and South America share a long history of exchanges, potentially pathogens. We used the worldwide parasite Toxoplasma gondii to test hypothesis historical influence on pathogen genetic diversity in Benin, West African country with longstanding sea trade history. In Africa, T . spatial structure is still non-uniformly studied very few articles have reported strain fauna clinical forms human toxoplasmosis so far, even diaspora. Sera from 758...
In sub-Saharan Africa, few studies have addressed the environmental determinants of incidence Toxoplasma gondii infection. Free-range chickens are regarded as sensitive indicators for contamination with T. oocysts due to their ground-feeding behavior and been used sentinels. A cross-sectional study was conducted from January April 2018 estimate seroprevalence infection in free-range Senegal, West using modified agglutination test. Sampling performed two regions country: Saint-Louis, a...
Assessing the prevalence of toxoplasmosis in pregnant women and associated risk factors is first step defining policy for prevention congenital a given population. An epidemiological study was conducted during prenatal consultations at CHU-MEL Cotonou (Benin) between September 2018 April 2021 recruited 549 to determine seroprevalence potential with Toxoplasma gondii infection. IgG/IgM antibodies were detected using an enzyme-linked fluorescence assay (ELFA) technique, IgG avidity test...
Toxoplasma gondii may cause fatal infection in European brown hares (Lepus europaeus). However, the role of this parasite terms mortality rate tularaemia endemic areas, amount parasites affected organs and circulating genotypes, is still unknown. In total, 36 (killed or found dead) were submitted for pathomorphological examination as a part national brucellosis monitoring. Tissue samples (lung, heart, liver, spleen kidney) tested by quantitative real-time PCR targeting 529 bp region T....
Toxoplasmosis, one of the most prevalent parasitic infections in humans and animals, is caused by intracellular protozoan parasite Toxoplasma gondii. Small mammals play a key role as intermediate reservoir hosts maintenance T. gondii life cycle. In this study, we estimated molecular prevalence provide genetic diversity data for 632 small sampled four areas Cotonou city, Benin. Both brain heart each individual were screened through gondii-targeting qPCR, positive samples then genotyped using...
Abstract Toxoplasma gondii is an ubiquitous highly prevalent zoonotic protozoan. Cats are the definitive hosts, while all other warm-blooded animals intermediate hosts for this parasite. Commensal rodents, being main preys of cats, probably major reservoir T. gondii. Rodents often develop dormant tissue cysts after ingestion oocysts shed in environment by cats form contaminated feces. Experimental evidence that vertical transmission can be sufficient to perpetuation between generations mice...
ABSTRACT Toxoplasma gondii is a cyst-forming apicomplexan parasite of virtually all warm-blooded species, with true cats (Felidae) as definitive hosts. It the etiologic agent toxoplasmosis, disease causing substantial public health burden worldwide. Its wide range host species and its global occurrence probably complicate study evolutionary history, conflicting scenarios have been proposed to explain current distribution. In this study, we analyse set 156 genomes (including 105 new genomes)...