A5021595703- Malaria Research and Control
- Mosquito-borne diseases and control
- Parasite Biology and Host Interactions
- Primate Behavior and Ecology
- Evolution and Genetic Dynamics
- Genetic diversity and population structure
- Vector-borne infectious diseases
- Viral Infections and Vectors
- Zoonotic diseases and public health
- Bird parasitology and diseases
- Agriculture and Rural Development Research
- Aging, Elder Care, and Social Issues
- French Urban and Social Studies
- Parasites and Host Interactions
- Wildlife Ecology and Conservation
- Animal Behavior and Reproduction
- HIV Research and Treatment
- Viral gastroenteritis research and epidemiology
- Insect symbiosis and bacterial influences
- Toxoplasma gondii Research Studies
- Aquaculture disease management and microbiota
- Herpesvirus Infections and Treatments
- Plant and animal studies
- Trypanosoma species research and implications
- Helminth infection and control
Université de Montpellier
2014-2025
Institut de Recherche pour le Développement
2015-2025
Centre National de la Recherche Scientifique
2016-2025
Maladies Infectieuses et Vecteurs: Écologie, Génétique, Évolution et Contrôle
2015-2025
Nelson Mandela University
2022-2025
Université Claude Bernard Lyon 1
2023-2025
Centre International de Recherches Médicales de Franceville
2013-2024
Agropolis International
2006-2023
Ecologie & Evolution
2021-2022
Laboratoire Mathématiques, Image et Applications
2022
Summary The spread of antimicrobial resistance is major concern for human health and leads to growing economic costs. While it increasingly hypothesized that wildlife could play an important role in antimicrobial‐resistant bacteria dynamics, empirical data remain scarce. present work builds on a systematic review the available order highlight main information we have suggest research pathways should be followed if aim fill gaps our current knowledge. To achieve this goal, address four...
Elucidation of the evolutionary history and interrelatedness Plasmodium species that infect humans has been hampered by a lack genetic information for three human-infective species: P. malariae two ovale (P. o. curtisi wallikeri). These are prevalent across most regions in which malaria is endemic often undetectable light microscopy, rendering their study human populations difficult. The exact relationship these to other contested. Using new reference genome manually curated draft genome, we...
Plasmodium reichenowi, a chimpanzee parasite, was until very recently the only known close relative of falciparum, most virulent agent human malaria. Recently, gaboni, another closely related discovered, suggesting that diversity circulating in great apes Africa might have been underestimated. It also shown P. reichenowi is geographically widespread and genetically diverse parasite world falciparum fully included within much broader genetic reichenowi. The evidence indicates all extant...
Plasmodium falciparum is the major human malaria agent responsible for 200 to 300 million infections and one three deaths annually, mainly among African infants. The origin evolution of this pathogen within lineage still unresolved. A single species, P. reichenowi, which infects chimpanzees, known be a close sister falciparum. Here we report discovery new species infecting Hominids. This has been isolated in two chimpanzees (Pan troglodytes) kept as pets by villagers Gabon (Africa). Analysis...
Plasmodium falciparum causes most human malaria deaths, having prehistorically evolved from parasites of African Great Apes. Here we explore the genomic basis P. adaptation to hosts by fully sequencing genome closely related chimpanzee parasite species reichenowi, and obtaining partial sequence data a more distantly (P. gaboni). The close relationship between reichenowi is emphasized almost complete conservation synteny, but against this strikingly conserved background observe major...
Significance Sickle cell disease (SCD) is a major cause of death for young children in Africa, which the World Health Organization has declared public health priority. It increasingly spreading outside Africa because population migrations, and, thus, it will become near future global concern. therefore important to understand how this genetic disorder maintained human populations. Although association between Plasmodium falciparum malaria and SCD well known, strength far from known. Using an...
The origin of Plasmodium falciparum in South America is controversial. Some studies suggest a recent introduction during the European colonizations and transatlantic slave trade. Other evidence—archeological genetic—suggests much older origin. We collected analyzed P. isolates from different regions world, encompassing distribution range parasite, including populations sub-Saharan Africa, Middle East, Southeast Asia, America. Analyses microsatellite SNP polymorphisms show that are subdivided...
Plasmodium vivax is considered to be absent from Central and West Africa because of the protective effect Duffy negativity. However, there are reports persons returning these areas infected with this parasite observations suggesting existence transmission. Among possible explanations for apparent paradox, a zoonotic reservoir has been proposed. May great apes reservoir? We analyze mitochondrial nuclear genetic diversity P. parasites isolated in compare it travelers regions Africa, as well...
Recent studies have highlighted the large diversity of malaria parasites infecting African great apes (subgenus Laverania) and their strong host specificity. Although existence genetic incompatibilities preventing cross-species transfer may explain specificity, vectors with a high preference for determined represents another possibility. To test this hypothesis, we undertook 15-mo-long longitudinal entomological survey in two forest regions Gabon, where wild live, at different heights under...
Abstract Many pathogens have the capacity to infect multiple hosts. Multi-species epidemiological systems are characterized by populations that interact and perform different functions in pathogen transmission maintenance. This study investigated dynamics of foot-and-mouth disease (FMD) virus cattle goats their respective circulation within sympatric livestock adjacent wildlife areas Zimbabwe. Through year-long longitudinal serological monitoring, spatial distributions FMD antibodies...
Journal Article DISPERSAL IN A PARASITIC WORM AND ITS TWO HOSTS: CONSEQUENCE FOR LOCAL ADAPTATION Get access Franck Prugnolle, Prugnolle GEMI, Equipe ESS, UMR‐2724 CNRS‐IRD, centre IRD, 911 avenue Agropolis, BP 64501, 34394 Montpellier Cedex 5, France Search for other works by this author on: Oxford Academic Google Scholar André Théron, Théron CBETM, UMR 5555 CNRS‐UP, Université de Perpignan, 52 Av. Villeneuve, 66860 Jean Pierre Pointier, Pointier Roula Jabbour‐Zahab, Jabbour‐Zahab Philippe...
Recent molecular exploration of the Plasmodium species circulating in great apes Africa has revealed existence a large and previously unknown diversity . For instance, gorillas were found to be infected by parasites closely related falciparum , suggesting that human malignant malaria agent may have arisen after transfer from gorillas. Although this scenario is likely light data collected apes, it remained ascertained whether P. -related infect other nonhuman primates Africa. Using tools, we...