A5007954356- X-ray Diffraction in Crystallography
- Crystallization and Solubility Studies
- Analytical Chemistry and Chromatography
- Chromatography in Natural Products
- Mass Spectrometry Techniques and Applications
- Microfluidic and Capillary Electrophoresis Applications
- Molecular Sensors and Ion Detection
- Metal complexes synthesis and properties
- Computational Drug Discovery Methods
- Asymmetric Hydrogenation and Catalysis
- Radioactive element chemistry and processing
- Protein purification and stability
- Crystallography and molecular interactions
- Various Chemistry Research Topics
University of Szeged
2019-2024
High-performance liquid chromatography-based enantioseparation of newly prepared azole analogs monoterpene lactones and amides was studied. Effects additives mobile phase composition were evaluated both in normal polar organic modes. Applying amylose tris-(3,5-dimethylphenylcarbamate) selector modes acid base found to affect the peak profiles, without significantly influencing enantiorecognition ability studied selector. In most cases, differences observed retention times...
Synthesis of organometallic half-sandwich polypyridyl Ru and Rh complexes. Anticancer activity against resistant cancer cell lines effects ligand methylation on aqueous chemistry structure.
The enantioselective separation of newly synthesized fluorine-substituted β-phenylalanines has been performed utilizing Cinchona alkaloid-based ion-exchanger chiral stationary phases. Experiments were designed to study the effect eluent composition, counterion content, and temperature on chromatographic properties in a systematic manner. Mobile phase systems containing methanol or mixtures acetonitrile together with acid base additives ensured highly efficient enantioseparations....
New amino, thio, and oxy derivatives of monoterpene lactones, amides, esters have been synthesized their enantioselective separations were investigated on seven covalently immobilized polysaccharide-based chiral stationary phases. The effects basic additives, different short-chain alcohols, the influence temperature chromatographic behavior studied. In addition, relationships between structure selector selectand parameters explored to reveal mechanistic details recognition. Experiments...
New, pharmacologically interesting chiral amino compounds, namely, stereoisomers of α-hydroxynaphthyl-ß-carboline, benz[d]azepine and benz[c]azepine analogs as well N-α-hydroxynaphthylbenzyl-substituted isoquinolines were enantioseparated by high-performance liquid chromatographic subcritical fluid methods on polysaccharide-based stationary phases. Separation the was optimized in both chromatography normal phase modes investigating effects composition bulk solvent, temperature, structures...
Abstract Solution speciation of Rh(η 5 ‐C Me ), Ru(η 6 ‐ p ‐cymene) and ‐toluene) complexes 2,4‐pyridinedicarboxylic acid (2,4‐dipicH 2 ) was studied compared to that 2‐picolinic (picH) in addition their reactivity towards chloride bromide ions, 1‐methylimidazole guanosine. Structures [Rh(η )(2,4‐dipicH)Cl] ⋅ 3H O ( 1 2[Ru(η ‐toluene)(2,4‐dipicH)Cl] [Ru(η ‐toluene)(2,4‐dipic)] 3 7H were analyzed by X‐ray diffraction. show typical piano stool geometry, while is a triangular complex stabilized...