A5045210326- Breast Cancer Treatment Studies
- Breast Lesions and Carcinomas
- Global Cancer Incidence and Screening
- Breast Implant and Reconstruction
- Economic and Financial Impacts of Cancer
- Cancer Treatment and Pharmacology
- BRCA gene mutations in cancer
- Advances in Oncology and Radiotherapy
- HER2/EGFR in Cancer Research
- Cancer Diagnosis and Treatment
- Cancer and Skin Lesions
- Health Systems, Economic Evaluations, Quality of Life
- Estrogen and related hormone effects
- Advanced Breast Cancer Therapies
- Cancer Risks and Factors
- Radiomics and Machine Learning in Medical Imaging
- MRI in cancer diagnosis
- Cancer Genomics and Diagnostics
- Nonmelanoma Skin Cancer Studies
- Multiple and Secondary Primary Cancers
- COVID-19 and healthcare impacts
- Cancer survivorship and care
- Reconstructive Surgery and Microvascular Techniques
- Glutathione Transferases and Polymorphisms
- Drug Transport and Resistance Mechanisms
Fox Chase Cancer Center
2016-2025
American College of Surgeons
2016-2024
Temple University Health System
2017-2024
Einstein Healthcare Network
2020
Creative Commons
2020
Temple University
2017
Memorial Sloan Kettering Cancer Center
2013
Society of Surgical Oncology
2012
Philadelphia University
2009-2010
Palo Alto Institute
2004
Time to surgery (TTS) is of concern patients and clinicians, but controversy surrounds its effect on breast cancer survival. There remains little national data evaluating the association.
Abstract The COVID-19 pandemic presents clinicians a unique set of challenges in managing breast cancer (BC) patients. As hospital resources and staff become more limited during the pandemic, it becomes critically important to define which BC patients require urgent care can wait for treatment until is over. In this Special Communication, we use expert opinion representatives from multiple organizations categorize into priority levels (A, B, C) urgency across all specialties. Additionally,...
To prospectively determine if estrogen receptor (ER)-negative human epidermal growth factor type 2 (HER2)-positive and ER-negative HER2-negative breast cancers have distinguishing clinical imaging features with use of retrospectively identified patients tissue samples.This HIPAA-compliant study was institutional review board approved. Informed consent obtained from living waived for deceased patients. Mean patient age at diagnosis 53 years (range, 31-84 years). Clinical history;...
Although no specific delay threshold after diagnosis of breast cancer has been demonstrated to affect outcome, delays can cause anxiety, and surgical waiting time suggested as a quality measure. This study was performed determine the interval from presentation surgery in Medicare patients with nonmetastatic invasive who did not receive neoadjuvant chemotherapy factors associated longer surgery.Medicare claims linked Surveillance, Epidemiology, End Results data were reviewed for between first...
Purpose: Regional lymph node status is the strongest prognostic determinant in early-stage melanoma. Lymphatic mapping and sentinel lymphadenectomy (LM/SL) standard to stage regional nodes because it accurate minimally morbid, yet its role for thin (≤ 1.5 mm) primary melanomas unknown. Patients Methods: Our melanoma database of more than 10,000 patients was reviewed with ≤ 1.50 mm thick who underwent LM/SL. All had lymphoscintigrams LM/SL via dye alone or radiopharmaceutical. tumor-positive...
Abstract Resistance to natural product chemotherapy drugs is a major obstacle successful cancer treatment. This type of resistance often acquired in response drug exposure; however, the mechanisms this adverse reaction are complex and elusive. Here, we have studied Adriamycin, Vinca alkaloids, etoposide MCF-7 breast cells, KB-3-1 epidermoid carcinoma other cell lines determine if there an association between expression glucosylceramide synthase, enzyme catalyzing ceramide glycosylation...
PURPOSE: The preoperative placement of prophylactic ureteral catheters in operations the distal colon is both commonplace and controversial. We assessed frequency, safety, effectiveness their use over a five one-half-year period teaching hospital. METHODS: charts 561 consecutive patients who underwent sigmoid or rectosigmoid colectomy from 1986 to 1991 were analyzed for age, sex, diagnosis, type colectomy, catheters, complications. RESULTS: Ureteral catheterization was attempted 92 (16.4...
Abstract Background Although treatment delays have been associated with survival impairment for invasive breast cancer, this has not thoroughly investigated ductal carcinoma in situ (DCIS). With trials underway to assess whether DCIS can remain unresected, study was performed determine longer times surgery are or increased invasion. Methods A population-based of prospectively collected national data derived from women a clinical diagnosis between 2004 and 2014 conducted using the National...
There is a growing need for short-term and cost-effective bioassay to assess the efficacy of potential chemo-preventive agents. We report that induction glutathione (GSH) S-transferase π (mGSTP1-1) by agent can be used as reliable marker its in retarding chemical carcinogenesis induced benzo(a)pyrene (BP), which widespread environmental pollutant believed risk factor human carcinogenesis. This conclusion based on 1) relative contribution mGSTP1-1 liver forestomach female A/J mice...
Abstract Background Methylene blue (MB) dye has been used for lymphatic mapping/sentinel lymphadenectomy (LM/SL) in staging of melanoma and breast cancer. It noted to cause skin necrosis, but its more mild adverse effects from intraparenchymal injections are not well characterized. Methods Patients undergoing LM/SL cancer were reviewed, with attention devoted manifestations. mastectomies excluded rule out changes flap devascularization. All patients injected intraparenchymally. Results...