A5019362849- Genetics and Neurodevelopmental Disorders
- Cellular transport and secretion
- Enhanced Oil Recovery Techniques
- Plant-Microbe Interactions and Immunity
- Ubiquitin and proteasome pathways
- Hippo pathway signaling and YAP/TAZ
- Congenital heart defects research
- RNA regulation and disease
- Polymer Surface Interaction Studies
- Genomics and Rare Diseases
- Lysosomal Storage Disorders Research
- Mechanical and Optical Resonators
- Cellular Mechanics and Interactions
- Adhesion, Friction, and Surface Interactions
- Hydrocarbon exploration and reservoir analysis
- Cyclone Separators and Fluid Dynamics
- Petroleum Processing and Analysis
- Silk-based biomaterials and applications
- Neurobiology and Insect Physiology Research
- Cerebrovascular and genetic disorders
- Mineral Processing and Grinding
- Fungal and yeast genetics research
- Metalloenzymes and iron-sulfur proteins
- Hereditary Neurological Disorders
- Plant tissue culture and regeneration
Lanzhou Jiaotong University
2025
University of Science and Technology of China
2024
Texas Children's Hospital
2022-2024
Baylor College of Medicine
2022-2024
Neurological Research Institute
2022-2024
China Agricultural University
2009-2024
China University of Petroleum, Beijing
2020-2024
Zhejiang Normal University
2024
University of Jinan
2023
China University of Mining and Technology
2021-2022
Transition metal dichalcogenide (TMD) nanosheets have evoked enormous research enthusiasm and shown increased potentials in the biomedical field. However, a great challenge lies high-throughput, large-scale, eco-friendly preparation of TMD nanosheet dispersions with high quality. Herein, we report universal polyphenol-assisted strategy to facilely exfoliate various TMDs into monolayer or few-layer nanosheets. By optimizing exfoliation condition molybdenum disulfide (MoS2), yield...
Mussel-inspired polydopamine (PDA) coatings have been broadly exploited for constructing functional membrane surfaces. One-step codeposition of PDA with antifouling polymers, especially zwitterionic has regarded as a promising strategy fabricating However, one challenge is that the usually slow process over 10 h or even several days. Herein, we report CuSO4/H2O2 able to notably accelerate poly(sulfobetaine methacrylate) (PSBMA). In our case, PSBMA facilely anchored polypropylene microporous...
Surface modification has been well recognized as a promising strategy to design and exploit diversified functional materials. However, conventional strategies usually suffer from complicated manufacture procedures lack of universality. Herein, facile, robust, versatile approach is proposed achieve the surface functionalization using dopamine acrylate monomers via one-step polymerization codeposition process. The gel permeation chromatography, proton nuclear magnetic resonance, liquid...
The structurally conserved but sequence-unrelated MAX ( Magnaporthe oryzae avirulence and ToxB-like) effectors AVR1-CO39 AVR-PikD from the blast fungus M. are recognized by rice nucleotide-binding domain leucine-rich repeat proteins (NLRs) RGA5 Pikp-1, respectively. This involves, in both cases, direct interaction of effector with a heavy metal-associated (HMA) integrated (ID) NLR. Here, we solved crystal structures C-terminal fragment carrying HMA ID (RGA5_S), alone, complex compared it to...
Plant nucleotide-binding and leucine-rich repeat (NLR) receptors recognize avirulence effectors directly through their integrated domains (IDs) or indirectly via the effector-targeted proteins. Previous studies have succeeded in generating designer NLR with new recognition profiles by engineering IDs targeted proteins based on prior knowledge of interactions effectors. However, it is yet a challenge to design plant receptor capable recognizing that function unknown mechanisms. Several rice...
Abstract Some plant sensor nucleotide-binding leucine-rich repeat (NLR) receptors detect pathogen effectors through their integrated domains (IDs). Rice RGA5 NLR recognizes its corresponding AVR-Pia and AVR1-CO39 from the blast fungus Magnaporthe oryzae direct binding to heavy metal-associated (HMA) ID trigger RGA4 helper NLR-dependent resistance in rice. Here, we report a mutant of named HMA5 that confers complete transgenic rice plants M. strains expressing noncorresponding effector...
Nanofiltration membranes (NFMs) with a high water permeation flux and salt rejection are extremely desirable due to their low energy consumption superior separation efficiency in practical applications. Herein, cellulose nanocrystals (CNCs) prepared by the sulfuric acid hydrolysis of microcrystalline were directly incorporated aqueous solution piperazine for fabricating thin film nanocomposite (TFN) NFMs interfacial polymerization. The as-fabricated TFN exhibit obviously rougher more...
This is the first time gorgeous structural colors have been presented from polydopamine-based coatings<italic>via</italic>a facile liquid phase deposition.
Zwitterionic polymers are continually suggested as promising alternatives to tune the surface/interface properties of materials in many fields because their unique molecular structures. Tremendous efforts have been devoted immobilizing zwitterionic (polyzwitterions, PZIs) on material surfaces. However, these usually suffer from cumbersome and time-consuming procedures. Herein we report a one-step strategy facilely achieve bioinspired polydopamine/polyzwitterion (PDA/PZI) coatings various...
Basement membranes (BMs) are thin sheet-like specialized extracellular matrices found at the basal surface of epithelia and endothelial tissues. They have been conserved across evolution required for proper tissue growth, organization, differentiation maintenance. The major constituents BMs two independent networks Laminin Type IV Collagen in addition to proteoglycan Perlecan glycoprotein Nidogen/entactin (Ndg). ability Ndg bind vitro Laminin, both with key functions during embryogenesis,...
In this work, floating-gate organic field-effect transistor memory using the n-type semiconductor poly-{[N,N′-bis(2-octyldodecyl) naphthalene-1,4,5,8-bis (dicarbo- ximide)-2,6-dili]-alt-5,5′-(2,2′-bithiophene)} (N2200) as a charge-trapping layer is presented. With assistance of technology computer-aided design (TCAD) tool (Silvaco-Atlas), storage characteristics device are numerically simulated by carrier injection and Fower–Nordheim (FN) tunneling models. The shift in transfer...
In order to study the microscopic oil displacement mechanism of polymeric surfactant in chemical cold flooding for heavy oil, indoor visualization experiments were carried out. The experiment was conducted by using water, osmotic modified displacing agent (a kind surfactant) and water-in-oil emulsion (obtained mixing oil) as phases enhance recovery reservoir. experimental results show that can increase viscosity water phase, reduce water-oil mobility ratio, expand swept area, there is no...
SUPT16H encodes the large subunit of FAcilitate Chromatin Transcription (FACT) complex, which functions as a nucleosome organizer during transcription. We identified two individuals from unrelated families carrying de novo missense variants in SUPT16H. The probands exhibit global developmental delay, intellectual disability, epilepsy, facial dysmorphism and brain structural abnormalities. used Drosophila to characterize variants: p.T171I p.G808R. Loss fly ortholog, dre4, causes lethality at...
Abstract Recovery in low permeability oil reservoirs is challenging because they are often high fractured and oil-wet. Microemulsion-forming surfactant solutions, which can replace from tight matrix by imbibition, have been verified as effective enhanced recovery fluids for reservoirs. To better understand the mechanisms of oil-wet, rocks using microemulsion-forming surfactants, microfluidic experiments including single channel micromodel tests imbibition could visualize in-situ phase...
The existing researches on surfactant micellar solutions mainly focus the formulation optimization and core flooding test, types mechanisms of cleanup additives suitable for low permeability reservoir remain unclear. flowback efficiencies different were evaluated by experiments, a multi-level pore-throat system micromodel characterizing structures was made, experiments brine salinities conducted with to show oil process in micron pores under effect solution visually reveal enhancing...