A5044589650- Functional Brain Connectivity Studies
- Treatment of Major Depression
- Bipolar Disorder and Treatment
- Tryptophan and brain disorders
- Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
- Attention Deficit Hyperactivity Disorder
- Identity, Memory, and Therapy
- Electrolyte and hormonal disorders
- Spaceflight effects on biology
- Child and Adolescent Psychosocial and Emotional Development
- Posttraumatic Stress Disorder Research
- COVID-19 and Mental Health
- Electroconvulsive Therapy Studies
- Advanced MRI Techniques and Applications
- EEG and Brain-Computer Interfaces
- Educational and Psychological Assessments
- Obsessive-Compulsive Spectrum Disorders
- Neural dynamics and brain function
- Neuroscience and Neuropharmacology Research
- Mental Health Research Topics
- Family Support in Illness
Duke University
2021-2025
First Affiliated Hospital of Jinan University
2020-2022
Jinan University
2017-2020
Major depressive disorder (MDD) is frequently associated with cognitive deficits and high copper levels. Dysfunction of N-methyl-d-aspartate (NMDA) receptors has been postulated to underlie MDD pathogenesis. This study sought investigate the curative effect NMDA receptor antagonist memantine on in depression underlying mechanisms.Adult male Sprague-Dawley rats received corticosterone (CORT) (20 mg/kg) bi-weekly via subcutaneous injection and/or gluconate (7 daily intragastric administration....
The practice-based evidence suggests that it is possible to use eye movement desensitization and reprocessing (EMDR) treat major depressive disorder (MDD), but its specific efficacy unknown. A systematic search was carried out for randomized controlled trials comparing EMDR with a control condition group in MDD patients. Two meta-analyses were conducted, symptom reduction as primary outcome remission exploratory outcome. Eight studies 320 participants included this meta-analysis. first...
Background: Cognitive deficit is acknowledged as a core feature of clinical manifestations bipolar disorder (BD). However, the underlying mechanism cognitive impairment in II depression has remained uncertain. We aim to determine association impairments with biochemical metabolism using proton magnetic resonance spectroscopy (1H-MRS) and battery neuropsychological testing. Methods: The current study was designed assess four domains sample 110 patients healthy controls, 6 tests, including...
Abstract Background Depressive symptoms could be similarly expressed in bipolar and unipolar disorder. However, changes cognition brain networks might quite distinct. We aimed to find out the difference neural mechanism of impaired working memory patients with Method According diagnostic criteria II disorder Diagnostic Statistical Manual Mental Disorders, Fifth Edition (DSM-5) assessments, 13 depression (BP II), 8 (UD) 15 healthy controls (HC) were recruited study. used 2-back tasks magnetic...
Objective To investigate the differences of working memory and brain biochemical metabolism between untreated obsessive-compulsive disorder (OCD) patients comorbid with without major depressive (MDD) by proton magnetic resonance spectroscopy (1H-MRS). Methods Thirty-five OCD, 38 OCD MDD, 41 healthy controls were studied in our study. 2-back, visual space test (VSMT), digit span (DST) Stroop color word (SCWT) performed to evaluate memory. And 3 groups also measured levels...