A5100442869- Functional Brain Connectivity Studies
- Chronic Kidney Disease and Diabetes
- Renal Diseases and Glomerulopathies
- Advanced Neuroimaging Techniques and Applications
- Nutrition and Health in Aging
- Dialysis and Renal Disease Management
- Neural dynamics and brain function
- Mental Health Research Topics
- Lysosomal Storage Disorders Research
- Pain Mechanisms and Treatments
- Gastrointestinal motility and disorders
- Body Composition Measurement Techniques
- Adipose Tissue and Metabolism
- Blood Pressure and Hypertension Studies
- Liver Disease Diagnosis and Treatment
- Advanced MRI Techniques and Applications
- Nitric Oxide and Endothelin Effects
- Salivary Gland Disorders and Functions
- Traditional Chinese Medicine Studies
- Frailty in Older Adults
- Erythropoietin and Anemia Treatment
- Pharmacological Effects and Toxicity Studies
- EEG and Brain-Computer Interfaces
- Gut microbiota and health
- Complex Network Analysis Techniques
Qilu Hospital of Shandong University
2016-2025
XinHua Hospital
2018-2025
Huazhong University of Science and Technology
2020-2025
Tongji Hospital
2020-2025
University of Twente
2024-2025
Xi'an Aeronautical University
2025
Changchun University of Chinese Medicine
2025
Fudan University
2024
Sun Yat-sen University
2015-2024
Lanzhou University
2020-2024
// Yanna Tang 1,2,3 ,* , Wenfeng Fang Yaxiong Zhang Shaodong Hong Shiyang Kang Yue Yan Nan Chen Jianhua Zhan Xiaobo He Tao Qin Ge Li 4 Wenyi 5 Peijian Peng and 1 Department of Medical Oncology, Sun Yat-sen University Cancer Center, Guangzhou, China 2 State Key Laboratory Oncology in South China, 3 Collaborative Innovation Center for Medicine, Stem Cells Tissue Engineering, University, The Fifth Affiliated Hospital Yat-Sen Zhu Hai, * These authors have contributed equally to this work...
Crescentic IgA nephropathy (IgAN), defined as >50% crescentic glomeruli on kidney biopsy, is one of the most common causes rapidly progressive GN. However, few studies have characterized this condition. To identify risk factors and develop a prediction model, we assessed data from patients ≥ 14 years old with IgAN who were followed 12 months. The discovery cohort comprised 52 center, validation 61 multiple centers. At mean serum creatinine (SCr) level ± SD was 4.3 3.4 mg/dl, percentage...
This was the first multicenter, cross-sectional survey to assess prevalence of anemia, patient awareness, and treatment status in China. Data patients with chronic kidney disease (CKD; age, 18–75 years; both out- inpatients) from 25 hospitals Shanghai, seeking medical at nephrology department, were collected between July 1, 2012 August 31, 2012. The prevalence, anemia nondialysis CKD (ND-CKD) assessed. Anemia defined as serum hemoglobin (Hb) levels ·12 g/dL women ·13 men. A total 2420 ND-CKD...
Immunoglobulin A (IgA) mediates mucosal responses to food antigens and the intestinal microbiome is involved in susceptibility pathogens, celiac disease, inflammatory bowel IgA nephropathy. We performed a genome-wide association study of serum levels 41,263 individuals diverse ancestries identified 20 significant loci, including 9 known 11 novel loci. Co-localization analyses with expression QTLs prioritized candidate genes for 14 Most loci encoded that produced immune defects abnormalities...
Upon differentiation induction of 3T3-L1 preadipocytes by a hormone mixture containing 1-isobutyl-3-methylxanthine, dexamethasone, and insulin, the undergo ∼2 rounds mitotic clonal expansion, which just precedes adipogenic gene expression program has been thought to be an essential early step for initiation. By inducing with each individual hormone, it was determined that expansion induced only insulin not 1-isobutyl-3-methylxanthine or dexamethasone. Cell number counting...
Despite the known morphological differences (e.g., brain shape and size) in brains of populations different origins age race), Chinese atlas is less studied. In current study, we developed a statistical based on multi-center high quality magnetic resonance imaging (MRI) dataset 2020 adults (18-76 years old). We constructed 12 from 20 year to 75 at 5 interval. New standard space, coordinates, area labels were further defined. The new was validated registration segmentation. It found that, as...
// Wenfeng Fang 1, 2, * , Shaodong Hong Nan Chen 3, Xiaobo He 3 Jianhua Zhan 2 Tao Qin Ting Zhou Zhihuang Hu Yuxiang Ma Yuanyuan Zhao Ying Tian Yunpeng Yang Cong Xue Yanna Tang Yan Huang Hongyun Li Zhang 1 State Key laboratory of Oncology in South China, Department Medical Oncology, Sun Yat-Sen University Cancer Center, Guangzhou, P. R. China Collaborative Innovation Center for Medicine, Yat-sen Guangdong, the Fifth Affiliated Hospital University, Zhuhai, These authors have contributed...
An intronic variant at the complement factor H ( CFH ) gene on chromosome 1q32 (rs6677604) associates with risk of IgA nephropathy (IgAN), but association signal has not been uniformly replicated in Han Chinese populations. We investigated whether causal sequence resides or neighboring H–related 1 CFHR1 and CFHR3 , which harbor an 84-kb combined deletion CFHR3,1Δ linkage disequilibrium rs6677604. Imputation 1000 Genomes Project data did suggest new single–nucleotide variants within cluster....
IntroductionTelitacicept, a transmembrane activator and cyclophilin ligand (CAML) interactor (TACI) fusion protein targeting B cell activating factor (BAFF) proliferation-inducing (APRIL), has proven efficacy in treating Immunoglobulin A (IgA) nephropathy. However, serum biomarkers that could predict the clinical response during treatment remain unclear.MethodsPlasma samples from 24 participants Phase 2 trial were collected at baseline after 4, 12, weeks, 8 placebo group, 9 160 mg 7 240...
Export Background and objectives High-quality epidemiologic data on the spectrum of biopsy-proven glomerular diseases among children are limited. This study aimed to determine profile temporal change in pediatric China. Design, setting, participants, & measurements We previously conducted a nationwide kidney biopsy survey including 71,151 patients over an 11-year period from January 2004 December 2014. A total 7962 younger than 18 years old 115 hospitals across China with were included this...
Objective: With limited data available on calcification prevalence in chronic kidney disease (CKD) patients dialysis, the China Dialysis Calcification Study (CDCS) determined of vascular/valvular (VC) and association risk factors Chinese with prevalent hemodialysis (HD) or peritoneal dialysis (PD).Methods: CKD undergoing HD/PD for ≥6 months were enrolled. Prevalence medical history documented at baseline. Coronary artery (CAC) was assessed by electron beam multi-slice computed tomography...
Paclitaxel-induced neuropathic pain (PINP) is a dose-limiting side effect and refractory to widely used analgesic drugs. Previous studies have demonstrated protective role of peroxisome proliferator-activated receptor gama (PPARγ) in pain. However, whether PPARγ activation could alleviate PINP remains be elucidated. Our previous study has validated the oltipraz, an nuclear factor erythroid-2 related 2 (Nrf2) activator, rat model PINP. In this study, we tested hypothesis that rosiglitazone,...