A5101995734- Genetics and Neurodevelopmental Disorders
- RNA modifications and cancer
- Congenital heart defects research
- Fibromyalgia and Chronic Fatigue Syndrome Research
- Heavy Metal Exposure and Toxicity
- Epigenetics and DNA Methylation
- Suicide and Self-Harm Studies
- Lipid metabolism and disorders
- Chemotherapy-induced cardiotoxicity and mitigation
- Inflammatory Biomarkers in Disease Prognosis
- Trace Elements in Health
- Nitric Oxide and Endothelin Effects
- Genetic Neurodegenerative Diseases
- Cholesterol and Lipid Metabolism
- Renin-Angiotensin System Studies
- Ferroptosis and cancer prognosis
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Blood Pressure and Hypertension Studies
- Genetic diversity and population structure
- Advanced Glycation End Products research
- Atherosclerosis and Cardiovascular Diseases
- Amphibian and Reptile Biology
- Peroxisome Proliferator-Activated Receptors
- Animal Behavior and Reproduction
Nanjing Medical University
2014-2025
Second Affiliated Hospital of Nanjing Medical University
2018-2025
Ningbo University
2024
China Jiliang University
2022
University of California, Irvine
2021
Dexrazoxane (DXZ) reduces cytotoxicity caused by Doxorubicin (DOX). However, the mechanism of DXZ in ferroptosis and cardiomyopathy remains unclear. This research, therefore, explores role DOX-induced rats. Kaplan–Meier survival analysis was performed rats treated DOX combination with inhibitor (FER-1) or other cell death–associated inhibitors. The ferroptosis, cardiotoxicity, expression high mobility group box 1 (HMGB1) FER-1 were determined hematoxylin eosin staining, echocardiographic...
Exposure to volatile organic compounds (VOCs) has been increasingly linked mental health disorders, but the relationship between VOCs exposure and suicidal ideation (SI) remains unclear. This study aims investigate link prevalence of SI. We analyzed data from 6966 participants in 2005-2020 National Health Nutrition Examination Survey. SI was assessed using ninth item Patient Questionnaire-9. Key urinary metabolites (mVOCs) associated with were identified elastic net regression models....
Mitochondrial biogenesis and function are controlled by anterograde regulatory pathways involving more than 1000 nuclear-encoded proteins. Transcriptional networks controlling the mitochondrial genes remain to be fully elucidated. Here, we show that histone demethylase LSD1 KO from adult mouse liver (LSD1-LKO) reduces expression of one-third all decreases function. LSD1-modulated methylation epigenetically regulates genes. Furthermore, gene protein nicotinamide mononucleotide...
Rosuvastatin has cardiac protective effects through its anti‑inflammatory effects. The nuclear protein high‑mobility group box 1 (HMGB1) can activate inflammatory pathways when released from dying cells. present study aimed to investigate the of rosuvastatin in adriamycin (ADR)‑treated rats. Adult male rats were randomized three groups: i) Control group, ii) ADR and iii) ADR+rosuvastatin group. Serum biochemical indices measured using an enzyme‑linked immunosorbent assay. Cardiac function...
Abstract The variegated toad-headed agama, Phrynocephalus versicolor, lives in the arid landscape of Chinese Gobi Desert. We analyzed populations from three different locations which vary substrate color and altitude: Heishankou (HSK), Guazhou County (GZ), Ejin Banner (EJN). is either light-yellow (GZ-y), yellow (EJN-y), or black (HSK-b); corresponding lizard population colors largely match their degree melanism. assembled P. versicolor genome sequenced over 90 individuals populations....
Proline Rich 12 (PRR12) protein is primarily expressed in the brain and localized nucleus. The variants