A5102806938- Ferroptosis and cancer prognosis
- Sepsis Diagnosis and Treatment
- Heavy Metal Exposure and Toxicity
- Trace Elements in Health
- Genetic Associations and Epidemiology
- RNA modifications and cancer
- Inflammatory Biomarkers in Disease Prognosis
- Venous Thromboembolism Diagnosis and Management
Peking University
2024-2025
Nanjing Health and Health Commission
2024
Nanjing Medical University
2024
Abstract Background Platelets play a critical role in hemostasis and inflammatory diseases. Low platelet count activity have been reported to be associated with unfavorable prognosis. This study aims explore the relationship between dynamics in-hospital morality among septic patients provide real-time updates on mortality risk achieve dynamic prediction. Methods We conducted multi-cohort, retrospective, observational that encompasses data eICU Collaborative Research Database (eICU-CRD)...
Background and aims: Hyperthyroidism is a clinical syndrome caused by the excessive production of thyroid hormones, which can have broad impact on overall health. We systematically investigated subsequent multisystem comorbidities associated with hyperthyroidism progression these conditions. Methods: After 1:4 propensity score matching, total 5,832 patients 22,579 controls from UK Biobank were included in this study. Phenome-wide association study was conducted to explore associations...
Abstract The role of molecular traits (e.g., gene expression and protein abundance) in the occurrence, development, prognosis lung cancer has been extensively studied. However, biomarkers other layers connections among various that influence risk remain largely underexplored. We conducted first comprehensive assessment associations between (i.e., DNA methylation, expression, metabolite) through epigenome-wide association study (EWAS), transcriptome-wide (TWAS), proteome-wide (PWAS)...