Longyao Zhang

ORCID: 0000-0002-0687-8397
Publications
Citations
Views
---
Saved
---
About
Contact & Profiles
Research Areas
  • Microfinance and Financial Inclusion
  • FinTech, Crowdfunding, Digital Finance
  • Islamic Finance and Banking Studies
  • Land Rights and Reforms
  • Lung Cancer Treatments and Mutations
  • Banking stability, regulation, efficiency
  • Energy, Environment, Economic Growth
  • Agriculture, Land Use, Rural Development
  • Radiomics and Machine Learning in Medical Imaging
  • Immune Cell Function and Interaction
  • Epigenetics and DNA Methylation
  • COVID-19 epidemiological studies
  • Digital Platforms and Economics
  • Lung Cancer Diagnosis and Treatment
  • Cancer Immunotherapy and Biomarkers
  • RNA modifications and cancer
  • Climate Change and Health Impacts
  • Lung Cancer Research Studies
  • Extracellular vesicles in disease
  • Environmental Impact and Sustainability
  • Fuzzy and Soft Set Theory
  • Agricultural Systems and Practices
  • Adipose Tissue and Metabolism
  • Ferroptosis and cancer prognosis
  • Pulmonary Hypertension Research and Treatments

Xinqiao Hospital
2022-2025

Army Medical University
2022-2025

Huazhong University of Science and Technology
2025

Nanjing Agricultural University
2018-2024

Nanjing Medical University
2022-2024

Chengdu Medical College
2023

China National Nuclear Corporation
2023

Center for Global Health
2022-2023

Southwest Petroleum University
2022-2023

Monash University
2022

A reliable risk prediction model is critically important for identifying individuals with high of developing lung cancer as candidates low-dose chest computed tomography (LDCT) screening. Leveraging a cutting-edge machine learning technique that accommodates wide list questionnaire-based predictors, we sought to optimize and validate model.

10.1016/j.ebiom.2023.104443 article EN cc-by-nc-nd EBioMedicine 2023-01-25

Purpose This study assesses the impact of microfinance experience on rural households’ subsequent bank credit access, defined as stepping-stone effect. We evaluate average impact, heterogeneity and mechanisms this effect draw policy implications. Design/methodology/approach Based 2018 survey data from 2,347 households in six Chinese provinces, uses IV-Probit model to Findings The increases probability obtaining by percentage points. Whether distinguished social capital or economic wealth, is...

10.1108/caer-01-2024-0026 article EN China Agricultural Economic Review 2025-02-07

Immune checkpoint inhibitors (ICIs) bring cancer patients tumor control and survival benefits, yet they also trigger immune-related adverse effects (irAEs), notably inhibitor-related pneumonitis (CIP), affecting about 5% of among whom 1–2% experiencing severe grade 3 or higher pneumonitis. Current research points to potential links with T cell subset dysfunction autoantibody increase, but the specific mechanisms underlying different grades CIP are understudied. Herein, we employed...

10.1007/s00262-025-03983-8 article EN cc-by-nc-nd Cancer Immunology Immunotherapy 2025-03-01

Background and aims: Hyperthyroidism is a clinical syndrome caused by the excessive production of thyroid hormones, which can have broad impact on overall health. We systematically investigated subsequent multisystem comorbidities associated with hyperthyroidism progression these conditions. Methods: After 1:4 propensity score matching, total 5,832 patients 22,579 controls from UK Biobank were included in this study. Phenome-wide association study was conducted to explore associations...

10.1530/ec-25-0066 article EN cc-by-nc-nd Endocrine Connections 2025-04-01

Based on official surveys conducted in 2010 and 2015, we study how the Chinese land titling reform beginning 2009 affected rural households' access to credit. We find that had differential credit effects across households. For households with above-average economic status (measured by area of cultivated land, level income, convenience bank visits), formal improved as a result reform. below-average economics status, reliance informal lessened. show availability collateral might have enhanced...

10.1080/00036846.2019.1644446 article EN Applied Economics 2019-07-21

Abstract High-fat diet (HFD) induced hepatic endoplasmic reticulum (ER) stress drives insulin resistance (IR) and steatosis. NK cells in adipose tissue play an important role the pathogenesis of IR obesity. Whether liver can induce ER thus promote obesity is still unknown. We demonstrate that HFD-fed mice display elevated production proinflammatory cytokine osteopontin (OPN) cells, especially CD49a+DX5– tissue-resident (trNK) cells. Obesity-induced stress, IR, steatosis are ameliorated by...

10.1002/jlb.3ma1119-173r article EN Journal of Leukocyte Biology 2019-12-12

Background: In late February 2022, the Omicron epidemic swept through Shanghai, and Shanghai government responded to it by adhering a dynamic zero-COVID strategy. this study, we conducted retrospective analysis of in explore timing performance control measures based on eventual size duration outbreak. Methods: We constructed an age-structured vaccination-stratified SEPASHRD model considering populations that had been detected or controlled before symptom onset. addition, retrospectively...

10.3390/tropicalmed8010039 article EN cc-by Tropical Medicine and Infectious Disease 2023-01-05

Background: Programmed cell death ligand 1 (PD-L1) blocking therapy has transformed the treatment of lung adenocarcinoma (LUAD), which significantly changed landscape immunotherapy. We aimed to explore specific subpopulations understand tumor progression and identify markers response PD-L1 therapy. Methods: Bulk, fluorescence-activated sorting (FACS), single-cell RNA (scRNA) sequencing were used profile CXCL13, EPSTI1, CDK1. The gene set variation analysis (GSVA) R package was utilized for...

10.21037/jtd-23-1164 article EN Journal of Thoracic Disease 2024-01-01

Nanodelivery systems combining photothermal therapy (PTT) and chemotherapy (CT), have been widely used to improve the efficacy biosafety of chemotherapeutic agents in cancer. In this work, we constructed a self-assembled nanodelivery system, formed by assembling photosensitizer (IR820), rapamycin (RAPA), curcumin (CUR) into IR820-RAPA/CUR NPs, realize for breast The NPs displayed regular sphere, with narrow particle size distribution, high drug loading capacity, good stability pH response....

10.3390/pharmaceutics15030849 article EN cc-by Pharmaceutics 2023-03-05

Abstract Based on official survey data from the Chinese Ministry of Agriculture and Rural Affairs collected in 2010 2015, we use difference‐in‐differences method to study how land titling reform beginning 2009 tiers (“the Reform”) affected demand, supply, access, rationing rural credit market. Our main findings are: (1) Reform increased households’ hidden but not their effective demand; (2) had no significant effect supply or a household's access; (3) likelihood non‐price rationing,...

10.1111/cjag.12273 article EN Canadian Journal of Agricultural Economics/Revue canadienne d agroeconomie 2021-04-08

Scrub typhus, caused by Orientia tsutsugamushi , is a serious public health problem in the Asia-Pacific region, threatening of more than one billion people. China countries with most disease burden scrub typhus. Previous epidemiological evidence indicated that meteorological factors may affect incidence but there was limited for correlation between local natural environment dominated and This study aimed to evaluate monthly typhus areas high prevalence using distributed lag non-linear model...

10.3389/fpubh.2022.992555 article EN cc-by Frontiers in Public Health 2022-10-19

We analyze group and individual lending using data from 26,579 loan-specific observations in 2014–2016 for CFPA Microfinance, China's largest microfinance institution (MFI). show that MFIs China have converted a large share of their liability portfolio into lending, particularly southern China. Changes loan contracts, especially size interest rates, significantly increased repayment risk, whereas long borrowing history improved performance. The higher risk was likely compensated by income....

10.1080/1540496x.2019.1636228 article EN Emerging Markets Finance and Trade 2019-07-18

Previous studies on the risk of pertussis exposure to atmospheric pollutants are still inconclusive. Air pollutant, meteorological data and epidemiological distribution cases in China during 2004–2018 were concluded this study. A distributed lag nonlinear model (DLNM) for a maximum 15 months was developed evaluate effects monthly air factors incidence. Then generalized additive (GAM) constructed explore interaction effect among pollutants, incidence stratified selected variables. total...

10.1016/j.heha.2022.100036 article EN cc-by-nc-nd Hygiene and Environmental Health Advances 2022-11-12

Download This Paper Open PDF in Browser Add to My Library Share: Permalink Using these links will ensure access this page indefinitely Copy URL DOI

10.2139/ssrn.4790090 preprint EN 2024-01-01

Recent breakthrough therapies have improved survival rates in non-small cell lung cancer (NSCLC), but a paradigm for prospective confirmation is still lacking. Patientdatasets were mainly downloaded from TCGA, CPTAC and GEO. We conducted downstream analysis by collecting metagenes generated 42-gene subtype classifiers to elucidate biological pathways. Subsequently, scRNA, eRNA, methylation, mutation, copy number variation depicted phenotype perspective. Enhancing the clinical translatability...

10.7717/peerj.18159 article EN cc-by PeerJ 2024-09-24
Coming Soon ...