Ka Y. Yuen

ORCID: 0000-0001-7406-8102
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About
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Research Areas
  • Veterinary Equine Medical Research
  • Viral Infections and Vectors
  • Reproductive Physiology in Livestock
  • Mosquito-borne diseases and control
  • Exercise and Physiological Responses
  • Antibiotic Resistance in Bacteria
  • Animal Disease Management and Epidemiology
  • Vector-Borne Animal Diseases
  • Microbial infections and disease research
  • Bacterial Identification and Susceptibility Testing
  • Pharmacological Effects and Assays
  • Antibiotics Pharmacokinetics and Efficacy
  • Viral Infections and Outbreaks Research
  • Adipose Tissue and Metabolism
  • Mitochondrial Function and Pathology
  • Rabies epidemiology and control
  • Urinary Tract Infections Management
  • Animal Virus Infections Studies
  • Marine animal studies overview
  • Zoonotic diseases and public health
  • Stress Responses and Cortisol
  • Thyroid Disorders and Treatments
  • Spaceflight effects on biology
  • Growth Hormone and Insulin-like Growth Factors
  • Effects of Environmental Stressors on Livestock

The University of Queensland
2020-2025

New South Wales Department of Primary Industries
2025

Abstract In 2022, a genotype IV (GIV) strain of Japanese encephalitis virus (JEV) caused an unprecedented and widespread outbreak disease in pigs humans Australia. As no veterinary vaccines against JEV are approved Australia all current human derived from (G) III strains, we used the recently described insect-specific Binjari (BinJV) chimeric flavivirus vaccine technology to produce GIV candidate. Herein describe production displaying structural prM E proteins isolate obtained stillborn...

10.1038/s41541-024-00903-2 article EN cc-by npj Vaccines 2024-07-31

Phenylbutazone is prescribed to manage pain caused by hyperinsulinemia-associated laminitis. reduces glucose and insulin concentrations in horses with dysregulation (ID) but the underlying mechanism of action unknown. Investigate effect phenylbutazone on tissue sensitivity horses. It hypothesized that reduced ID receiving are mediated a higher sensitivity. Fifteen light breed horses, including seven ID. Randomized cross-over study. Horses underwent modified frequently sampled intravenous...

10.1111/jvim.70028 article EN cc-by-nc-nd Journal of Veterinary Internal Medicine 2025-02-26

Ross River virus (RRV), the most medically and economically important arbovirus in Australia, has been prevalent infections humans for many years. Infected horses often suffer similar clinical symptoms. We conducted a prospective longitudinal study over 3.5-year period to investigate exposure dynamics of RRV three foal cohorts (n = 32) born subtropical region South East Queensland, between 2020 2022. RRV-specific seroconversion was detected 56% 18) foals with median time seroconversion,...

10.1017/s0950268824000554 article EN cc-by-nc-nd Epidemiology and Infection 2024-01-01

Urinary tract infections are a common diagnosis in dogs presenting to veterinary practice. Veterinarians often treat suspected empirically, either the absence of culture and susceptibility testing results or whilst waiting for them. This study aimed identify bacteria most frequently isolated from canine urinary samples their antimicrobial patterns South East Queensland (SEQ) help guide responsible empirical prescription by community this geographical location. Cumulative antibiograms were...

10.1111/avj.13333 article EN cc-by Australian Veterinary Journal 2024-04-24

Abstract Background Determination of plasma adrenocotrophic hormone (ACTH) concentration (endogenous or thyrotropin‐releasing [TRH] stimulation test) is the most commonly used diagnostic test for pituitary pars intermedia dysfunction (PPID) in horses. Because ACTH unstable, samples often are frozen to be shipped laboratories allow batch analysis research samples. However, effect multiple freeze‐thaw cycles on equine unknown. Objective To determine effects immunoreactive concentration....

10.1111/jvim.15771 article EN cc-by-nc-nd Journal of Veterinary Internal Medicine 2020-04-07

Pituitary pars intermedia dysfunction (PPID) is diagnosed by increased basal or post thyrotropin-releasing hormone (TRH) stimulation ACTH concentrations. known to be unstable; however, the effect of different temperatures and TRH on equine stability poorly described. In total, 15 horses, including 8 PPID positive (ACTH > 35 pg/mL at baseline >65 30 min after stimulation), were divided into 2 groups: 9, 5 positive, with concentrations 6, 3 Whole blood was stored for 1 h 4, 20, 30, 40, 70 °C....

10.3390/ani12030324 article EN cc-by Animals 2022-01-28

The increased frequency of extreme weather events due to climate change has complicated the epidemiological pattern mosquito-borne diseases, as host and vector dynamics shift adapt. However, little is known about seroprevalence common virus infections in horses Australia. In this study, serological surveys for multiple alphaviruses were performed on samples taken from 622 across two horse populations (racehorses residing University Queensland (UQ) campus) using gold standard neutralization...

10.3390/v14091846 article EN cc-by Viruses 2022-08-23

Prudent use of antimicrobials is paramount to slow the development resistance and for successful treatment. The cumulative antibiograms will allow evidence-based antimicrobial selection with consideration local patterns. We generated a “first-isolate-per-patient” antibiogram regional equine referral hospital. Bacterial organisms cultured from horses between 2011 2018, sample origin, susceptibilities, multidrug-resistant (MDR) status were tabulated. Of 1,176 samples, 50% culture positive....

10.1177/1040638720977478 article EN Journal of Veterinary Diagnostic Investigation 2020-11-28

Southern Hemisphere humpback whales accumulate persistent and toxic chemicals, which are transported to Antarctica through distant sources

10.1021/acs.est.3c10595 article EN Environmental Science & Technology 2024-07-03

Chronic oroantral fistulae (OAF) with secondary sinusitis can occur following repulsion of cheek teeth in horses.An 8-year-old Andalusian cross gelding presented an iatrogenic clinical crown fracture tooth 209, which underwent its apical portion (day 0). The horse was treated intramuscular penicillin and intravenous gentamicin (5 days), followed by oral trimethoprim-sulphonamide (10 days) then doxycycline (14 days). acute OAF created during the initial persisted; a chronic identified on day...

10.1111/avj.13136 article EN Australian Veterinary Journal 2021-12-02
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