- Greenhouse Technology and Climate Control
- Plant Physiology and Cultivation Studies
- Urban and spatial planning
- Leaf Properties and Growth Measurement
- 14-3-3 protein interactions
- Light effects on plants
- Carcinogens and Genotoxicity Assessment
- Ubiquitin and proteasome pathways
- Drug-Induced Hepatotoxicity and Protection
- Plant Reproductive Biology
- Linguistics and language evolution
- Cancer-related Molecular Pathways
- Cancer Cells and Metastasis
- Heart rate and cardiovascular health
- Animal Ecology and Behavior Studies
- Genomics and Chromatin Dynamics
- biodegradable polymer synthesis and properties
- RNA Research and Splicing
- Historical Linguistics and Language Studies
- Respiratory Support and Mechanisms
- Animal testing and alternatives
- Flowering Plant Growth and Cultivation
- Plant Molecular Biology Research
- Horticultural and Viticultural Research
- Linguistic research and analysis
National Agriculture and Food Research Organization
2007-2025
Western Region Agricultural Research Center
2019-2025
Robotics Research (United States)
2024
Iwate Medical University
2014-2023
IRYO Sosei University
2023
Institute of Vegetable and Floriculture Science
2008-2020
Ono Pharmaceutical (United Kingdom)
2016-2020
Kyoto University
1998-2016
Ono Pharmaceutical (Japan)
2011-2014
Tokyo University of Science
2004-2014
Increased heart rate (HR) is an independent risk factor for cardiovascular outcomes in chronic failure (HF). Ivabradine, anI
Background Successful recovery from acute lung injury requires inhibition of neutrophil influx and clearance apoptotic neutrophils. However, the mechanisms underlying remain unclear. We investigated ameliorative effects vascular endothelial growth factor (VEGF)-C/VEGF receptor 3 (VEGFR-3) signalling in macrophages lipopolysaccharide (LPS)-induced injury. Methods LPS was intranasally injected into wild-type transgenic mice. Gain loss VEGF-C/VEGFR-3 function experiments employed...
Automated crop monitoring using image analysis is commonly used in horticulture. Image-processing technologies have been several studies to monitor growth, determine harvest time, and estimate yield. However, accurate of flowers fruits addition tracking their movements difficult because location on an individual plant among a cluster plants. In this study, automated clip-type Internet Things (IoT) camera-based growth date prediction system was proposed designed for tomato cultivation....
Early fruit size prediction in greenhouse tomato ( Solanum lycopersicum L.) is crucial for growers managing cultivars to reduce the yield ratio of small-sized and stakeholders horticultural supply chain. We aimed develop a method early at harvest with machine learning algorithm, three models (Ridge Regression, Extra Tree Regrreion, CatBoost Regression) were compared using PyCaret package Python. For constructing models, weight estimated from diameter obtained over time each cumulative...
Although the mechanisms underlying benzene-induced toxicity and leukemogenicity are not yet fully understood, they likely to be complicated by various pathways, including those of metabolism, growth factor regulation, oxidative stress, DNA damage, cell cycle programmed death. With this as a background, we performed cDNA microarray analyses on mouse bone marrow tissue during after 2-week benzene exposure inhalation. Our goal was clarify hematotoxicity induced at level altered multigene...
The 14-3-3 proteins form a highly conserved family of dimeric that interact with various signal transduction and regulate cell cycle, apoptosis, stress response, malignant transformation. We previously demonstrated the β isoform promotes tumorigenicity angiogenesis rat hepatoma K2 cells. In this study, to analyze mechanism 14-3-3β-induced transformation, yeast two-hybrid screening was performed, novel 14-3-3β-binding factor, FBI1 (fourteen-three-three beta interactant 1), identified. vitro...
Low-cost heating is needed to reduce chilling injuries, costs, and CO2 emission during greenhouse tomato production. To acquire information about the physiological morphological effects of root-zone heating, an economical option at low air temperatures, we grew plants on a nutrient film technique hydroponic system in heated solution. We investigated short-term after transplanting long-term until harvest. measured plant growth, uptake, root activity (xylem exudation respiration rates),...
Uniform temperature throughout a greenhouse is recommended, as the present climate control method and many other studies have shown that gradient decreases vertically horizontally in greenhouse.However, recent research revealed roots, fruits, flowers, shoot-tips are more sensitive to changes than leaves stems, indicating uniform may not be necessary.In addition, energy-saving techniques do lead yield loss desirable reduce energy costs ensure sustainable production.In this paper, we review...
Background:Elevated heart rate (HR) is an independent risk factor for cardiovascular outcomes in various cardiac diseases, including failure (HF).Methods and Results:Randomized placebo-controlled study was conducted to evaluate the effects of ivabradine, Ifinhibitor, on resting HR 126 Japanese symptomatic HF patients with left ventricular ejection fraction ≤35%, ≥75 beats/min sinus rhythm, stable, optimal background treatment. Patients were randomly allocated into 3 groups: placebo; starting...
Abstract The Na + –Ca 2+ exchanger (NCX) plays a role in regulating intracellular Ca concentration, but little is known about NCX microglia. We examined mRNA expression of isoforms cultured rat microglia and the effect interferon‐γ (IFN‐γ) on activity. RT–PCR showed that all isoforms, NCX1–3, are expressed Ouabain monensin increased 45 uptake concentration microglia, suggesting presence activity reverse mode. Treatment with IFN‐γ (100 U/mL) caused biphasic increase transient by for 1 h was...
This research focused on three major questions regarding benzene-induced hematopoietic neoplasms (HPNs). First, why are HPNs induced equivocally and at only threshold level with low-dose benzene exposure despite the significant genotoxicity of even low doses both in experiments epidemiology? Second, is there no linear increase incidence high-dose a lower acute toxicity (LD(50) > 1000 mg/kg body weight; WHO, 2003, Benzene drinking-water. Background document for development WHO Guidelines...
CRIM1 is a membrane protein that has been reported to be related cell proliferation. expressed in renal carcinoma cells, but its involvement proliferation and malignant transformation remains unclear. We analyzed whether alterations the characteristics of cancer cells are observed following knockdown CRIM1. Decreased expression did not affect or anchorage-independent growth. The results wound healing invasion assays showed reduced increased cells' migratory invasive abilities. Expression...
We validated a model for predicting dry matter (DM) production in growing plants without the need destructive sampling with three tomato cultivars one-year experiment. In an attempt to improve DM, we managed temperature and CO2 concentration greenhouse as well leaf area index (LAI) of meet targets determined based on predictions. model, thus intercepted light is obtained by non-destructive, manual measurements width length number leaves. Light-use efficiency expressed function daytime...
To control the harvest date of strawberries, we constructed a device that can local fruit temperature and investigate effects cooling heating on maturation quality. Fruits were sequentially placing into thermally insulated tubs to during development. The average decreased by 4.1℃ increased 3.8℃ when compared with without control. number days from flowering (i.e., maturation) was strongly affected temperature, prolonging shortening Non-linear regression analysis revealed two formulas for...
Abstract The long‐term (1‐ and 2‐year) adverse tissue responses including tumor formation by subcutaneous implanation of polyurethanes (PUS) silicone (Sil) films intorats were compared. weight‐averaged molecular weights (M w ) the PUS prepared from 4,4′‐diphenylmethanediisocyanate, poly (tetramethyleneglycol) M, = 1000 1,4‐butanediol are 220,000 (U‐4), 124,000 (U‐6), 55,600 (U‐8). 50:50 mixed film U‐6 (U‐b/sil) was rollmixing noncured solution followed evaporation solvent heat‐curing at...
6-Pyruvoyl-tetrahydropterin synthase, which catalyzes the second step in biosynthesis of tetrahydrobiopterin, was purified approximately 18,000-fold to apparent homogeneity from rat liver. The molecular mass native enzyme estimated be 83 kDa by gel filtration. showed a single band on sodium dodecyl sulfate-polyacrylamide electrophoresis corresponding 17 kDa. Up 24 residues NH2-terminal sequence were determined Edman degradation, released amino acid at each step. These results indicate that...
The molecular mechanisms involved in neuronal/astroglial cell fate decisions during the development of mammalian central nervous system are poorly understood. Here, we report that PRP19β, a splice variant mouse PRP19α corresponding to yeast PRP19 protein, can function as neuron-astroglial switch retinoic acid-primed neural differentiation P19 cells. β-variant possesses an additional 19 amino acid residues inframe N-terminal region α-variant. forced expression α-variant RNA caused...