Alan W. Harris

ORCID: 0000-0001-7431-2013
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About
Contact & Profiles
Research Areas
  • Astro and Planetary Science
  • Planetary Science and Exploration
  • Stellar, planetary, and galactic studies
  • Astronomical Observations and Instrumentation
  • Solar and Space Plasma Dynamics
  • Isotope Analysis in Ecology
  • Atmospheric Ozone and Climate
  • Space Exploration and Technology
  • Astronomy and Astrophysical Research
  • Gamma-ray bursts and supernovae
  • Geology and Paleoclimatology Research
  • Astrophysics and Star Formation Studies
  • Cancer-related Molecular Pathways
  • Space Science and Extraterrestrial Life
  • Air Quality Monitoring and Forecasting
  • History and Developments in Astronomy
  • Space Satellite Systems and Control
  • Spacecraft and Cryogenic Technologies
  • Long-Term Effects of COVID-19
  • Astronomical and nuclear sciences
  • High-pressure geophysics and materials
  • Geomagnetism and Paleomagnetism Studies
  • Cell death mechanisms and regulation
  • Radio Astronomy Observations and Technology
  • Radiopharmaceutical Chemistry and Applications

Planet
2007-2023

Research!America (United States)
2012-2019

Neostem (United States)
2013

Space Science Institute
2003-2012

Paulsson (United States)
2011

Catalina Scientific (United States)
2011

Planetary Science Institute
1973-2009

Adam Mickiewicz University in Poznań
2008

Walter and Eliza Hall Institute of Medical Research
1983-2007

The Royal Melbourne Hospital
1981-2007

Impaired apoptosis is now recognized to be central tumor development. Bcl2, activated by chromosomal translocation in human follicular lymphoma, promotes oncogenesis inhibiting apoptosis. Bim, a distant proapoptotic relative, emerging as major physiologic antagonist of Bcl2. Here, we show that loss Bim oncogenic. protein levels were elevated the apoptosis-prone B lymphoid cells Eμ- Myc -transgenic mice, and -mutant mice had increased numbers IgM-bearing cells. -expressing deficient...

10.1073/pnas.0401471101 article EN Proceedings of the National Academy of Sciences 2004-04-12

DNA damage can cause mutations that contribute to cellular transformation and tumorigenesis. The p53 tumor suppressor acts protect the organism from by inducing either G1 arrest facilitate repair or activating physiological cell death (apoptosis). Consistent with this critical function of p53, mice lacking are predisposed developing tumors, particularly lymphoma. severe combined immune deficiency (scid) focus encodes catalytic subunit protein kinase (DNA-PKcs), a complex has role in response...

10.1101/gad.10.16.2055 article EN Genes & Development 1996-08-15

10.1016/0019-1035(83)90072-6 article EN Icarus 1983-04-01

10.1016/0014-4827(70)90527-6 article EN Experimental Cell Research 1970-06-01

Visible and near-infrared spectroscopic observations of the asteroid 1459 Magnya indicate that it has a basaltic surface. is at 3. 15 astronomical units (AU) from sun no known dynamical link to any family, nearby large asteroid, or 4 Vesta 2.36 AU, which only other asteroid. We show region belt around densely filled by mean-motion resonances, generating slow orbital diffusion processes providing potential mechanism for removing fragments may have been created on same parent body as Magnya....

10.1126/science.288.5473.2033 article EN Science 2000-06-16

10.1016/0019-1035(80)90084-6 article EN Icarus 1980-07-01
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