- Bone fractures and treatments
- Cancer-related molecular mechanisms research
- Knee injuries and reconstruction techniques
- Hip and Femur Fractures
- Spinal Cord Injury Research
- Total Knee Arthroplasty Outcomes
- Regulation of Appetite and Obesity
- MicroRNA in disease regulation
- Circular RNAs in diseases
- Osteoarthritis Treatment and Mechanisms
- RNA modifications and cancer
- Galectins and Cancer Biology
- Calpain Protease Function and Regulation
- Dermatologic Treatments and Research
- Shoulder Injury and Treatment
- Dietary Effects on Health
- Shoulder and Clavicle Injuries
- Medical and Biological Sciences
- Silk-based biomaterials and applications
- Wound Healing and Treatments
- Adipose Tissue and Metabolism
- dental development and anomalies
- Immune Response and Inflammation
- Orthopedic Infections and Treatments
- Immune cells in cancer
Jiangsu University
2009-2023
Affiliated Hospital of Jiangsu University
2009-2023
Osteosarcoma (OS) is a common primary bone malignancy. Long noncoding RNA HCG18 known to play an important role in variety of cancers. However, its OS and relevant molecular mechanisms are unclear.Real-time quantitative PCR was performed determine the expression target genes. Function experiments showed effects miR-365a-3p on cell growth.HCG18 increased lines. Moreover, vitro vivo demonstrated that knockdown inhibited proliferation. Mechanistically, defined as competing endogenous by...
Aims Tibial plateau fractures (TPFs) are complex injuries around the knee caused by high- or low-energy trauma. In present study, we aimed to define distribution and frequency of TPF lines using a 3D mapping technique analyze rationalization divisions employed frequently used classifications. Methods total, 759 adult patients with 766 affected knees were retrospectively reviewed. The fragments on CT multiplanar reconstructed, virtually reduced match model proximal tibia. heat was...
Few studies have reported a relationship between leptin induced by spinal cord injury (SCI) and healing bone tissue.To observe serum callus expression within the setting of fracture traumatic SCI.Seventy-two male Sprague Dawley rats were randomized equally into four groups: control, SCI group, fracture/SCI group. Rats sacrificed at 7, 14, 21, 28 days post-fracture/SCI. Serum was detected using radioimmunoassay 1, days, formation measured radiologically days. Callus analyzed means...
Orthopedic literature states that fractures of long bones, when associated with traumatic brain injuries, frequently heal excessive callus and faster than normal. Few studies, however, have reported these phenomena being induced by spinal cord injury (SCI). Our objective is to compare the extent rate healing long-bone in patients or without SCI. Subgroup comparisons were performed among SCI terms different levels SCI.The final mean volume formation union nailed femur determined...
Osteoarthritis (OA) is a frequently encountered debilitating joint disorder. Whether plexin C1 (PLXNC1) implicated in OA far from being investigated despite its well-documented pro-inflammatory property human diseases. The goal of this study to expound the specific role PLXNC1 and elaborate probable action mechanism.
About 1/3 of tibial plateau fractures are associated with proximal fibula fractures, but most often ignored. The aim this study was to precisely explain the classification and treatment strategies six injury types fibular column fractures.Patients ipsilateral treated in our hospital were retrospectively reviewed from Aug 2007 Mar 2020. Two experienced surgeons two radiologists divided into 6 according AO four-column nine-segment classification. scheme (surgically or conservatively treated)...
Objective To discuss and evaluate the arthroscopic suture bridge technique for treatment of full thickness rotator cuff tear.Methods Between January 2009 June 2010,22 cases full-thickness tears were treated by technique,and results analyzed statistically.Results All patients reviewed average follow-up period was 25.8 months (range,18 to 35 months).Average tear measured (3.60± 0.25) cm no anchor loosened.At last follow-up,the range active forward flexion,abduction,external rotation at side...