Costantino Parisi

ORCID: 0000-0001-7438-8034
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About
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Research Areas
  • Environmental Toxicology and Ecotoxicology
  • Congenital heart defects research
  • Water Quality and Pollution Assessment
  • Fish Biology and Ecology Studies
  • Heavy Metal Exposure and Toxicity
  • RNA modifications and cancer
  • Heavy metals in environment
  • Identification and Quantification in Food
  • Marine Ecology and Invasive Species
  • Constructed Wetlands for Wastewater Treatment
  • Plant Stress Responses and Tolerance
  • Marine Biology and Environmental Chemistry
  • Selenium in Biological Systems
  • Genomics and Rare Diseases
  • Rabbits: Nutrition, Reproduction, Health
  • Reproductive Health and Contraception
  • Sperm and Testicular Function
  • Fish Ecology and Management Studies
  • Physiological and biochemical adaptations
  • Moringa oleifera research and applications
  • CRISPR and Genetic Engineering
  • Aluminum toxicity and tolerance in plants and animals
  • Machine Learning in Bioinformatics
  • Plant tissue culture and regeneration
  • Allelopathy and phytotoxic interactions

International Institute of Molecular and Cell Biology
2019-2025

University of Naples Federico II
2019-2025

The ongoing rapid climate change, combined with the disturbance of fish breeding grounds, may impact reproduction by endangering successful and survival, thus affect viable sustainability in aquaculture systems as well sea. In this study we focus on biocomplexity response to change. Further, propose adaptive strategies, including technological advancements, using a noninvasive non-lethal approach, outline an assisted nutrigenomics approach mitigating reproductive risks posed This was done...

10.3390/w15040725 article EN Water 2023-02-12

The land use change can negatively impact ecosystems, enriching water and soil with heavy metals (HMs). fragile riparian areas along the Medjerda River of Northern Algeria are particularly affected by this phenomenon, biological tools able to combine information about both matrices be preferred in their monitoring. This research aimed evaluate suitability spiny toad (Bufo spinosus D.) as a biomonitor for assessing three different uses (agricultural (AGR), urban (URB), industrial (IND)...

10.3390/w16040538 article EN Water 2024-02-09

Abstract Congenital heart disease (CHD) is a prevalent condition characterized by defective development, causing premature death and stillbirths among infants. Genome-wide association studies (GWASs) have provided insights into the role of genetic variants in CHD pathogenesis through identification comprehensive set single-nucleotide polymorphisms (SNPs). Notably, 90–95% these reside noncoding genome, complicating understanding their underlying mechanisms. Here, we developed systematic...

10.1186/s12864-025-11232-6 article EN cc-by BMC Genomics 2025-01-21

A two-fold integrated research study was conducted; firstly, to understand the effects of copper (Cu) and zinc (Zn) on growth oxidative stress in Nile tilapia, Oreochromis niloticus; secondly, beneficial duckweed Lemna minor L. as a heavy metal remover wastewater. Experiments were conducted mesocosms with without duckweed. Tilapia fingerlings exposed Cu (0.004 0.02 mg L−1) Zn (0.5 1.5 fish fed for four weeks. We evaluated performance, hepatic DNA structure using comet assay, expression...

10.3390/w12112983 article EN Water 2020-10-24

The ageing process in living organisms is characterised by the accumulation of several deleterious changes occurring cells and tissues. increase reactive oxygen species with advancement age responsible for oxidative damage to proteins, lipids DNA, enhancing risk diseases. antioxidant response activation poly(ADP-ribosyl)ation represent first defences activated at all life stages counteract cell structures genomic material. regulation poly(ADP ribosyl)ation little known plants, especially...

10.3390/antiox8110528 article EN cc-by Antioxidants 2019-11-06

Lagoons play an important socio-economic role and represent a precious natural heritage at risk from fishing pressure chemical biological pollution. Our research focused on better understanding the discrimination of fish biodiversity, detection non-indigenous species, valorization commercial indigenous species Mellah lagoon (Algeria). Taxonomic characterization barcoding for all Inkscape schematic drawings most common are provided. A total 20 families 37 were recorded. The thermophilic Coris...

10.3390/w14040635 article EN Water 2022-02-18

Abstract Our study attempted to monitor the quality of water in Medjarda basin (Northeastern Algeria) and provide baseline information heavy metals as well a potential amphibian biosentinel, spiny toad, Bufo spinosus . We measured pH, temperature, dissolved oxygen biological demand levels toad skin using an atomic absorption flame spectrophotometer. Lead (Pb) concentration at all sites exceeded respectively 60 96 times standard reference values. The metal concentrations, descending order,...

10.1007/s12595-020-00342-6 article EN cc-by Proceedings of the Zoological Society 2020-09-21

A two-fold integrated research study was conducted; firstly, to understand effects of copper (Cu) and zinc (Zn) on the growth oxidative stress in Nile tilapia, Oreochromis niloticus; secondly, beneficial duckweed Lemna minor L. as a heavy metal remover from wastewater. Experiments were conducted mesocosms with without duckweed. Tilapia fingerlings exposed Cu (0.004 0.02 mg/L) Zn (0.5 1.5 fish fed for four weeks. We evaluated performance, hepatic DNA structure using comet assay, expression...

10.20944/preprints202009.0475.v1 preprint EN 2020-09-20

Male fertility is strongly affected by the overexpression of free radicals induced heavy metals. The aim this study was to evaluate potential antioxidant, anti-inflammatory, and gonado-protective effects natural compounds. Biochemical morphological assays were performed on male albino rats divided into five groups: a control group (water only), orally exposed metal mixture Pb-Cd-Hg-As alone three groups co-administered an aqueous extract Nigerian medicinal plant, Anonychium africanum...

10.3390/antiox13091028 article EN cc-by Antioxidants 2024-08-24

Abstract There is rising concern for the interaction of environmental contaminants with brain transcriptome and potential effect on reproductive processes. The present study sought to determine selenoprotein glutathione peroxidase 4 (gpx4) transcriptional activity in testis soil biosentinel, Podarcis sicula, through main phases cycle whether pharmaceuticals exert an endocrine disruption. Based gpx4 cloned amminoacids sequence (GenBank AEX09236.1.), we used a bioinformatic approach assess...

10.1002/mrd.23143 article EN Molecular Reproduction and Development 2019-04-07

Antifoulant paints were developed to prevent and reduce biofouling on surfaces immersed in seawater. The widespread use of these substances over the years has led a significant increase their presence marine environment. These compounds identified as environmental human threats. As result an international ban, research last decade focused developing new generation benign antifoulant paints. This review outlines detrimental effects associated with biocide versus eco-friendly antifoulants,...

10.3390/jmse10060792 article EN cc-by Journal of Marine Science and Engineering 2022-06-09

Abstract Congenital heart disease (CHD) is a prevalent condition characterized by defective development, causing premature death and stillbirths among infants. Genome-wide association studies (GWASs) have provided insights into the role of genetic variants in CHD pathogenesis through identification comprehensive set single-nucleotide polymorphisms (SNPs). Notably, 90-95% these reside noncoding genome, complicating understanding their underlying mechanisms. Here, we developed systematic...

10.1101/2024.03.20.24304537 preprint EN cc-by-nc medRxiv (Cold Spring Harbor Laboratory) 2024-03-22

Abstract Background Congenital heart disease (CHD) is a prevalent condition characterized by defective development, causing premature death and stillbirths among infants. Genome-wide association studies (GWASs) have provided insights into the role of genetic variants in CHD pathogenesis through identification comprehensive set single-nucleotide polymorphisms (SNPs). Notably, 90–95% these reside noncoding genome, complicating understanding their underlying mechanisms. Results In this study,...

10.21203/rs.3.rs-4136508/v1 preprint EN cc-by Research Square (Research Square) 2024-03-26
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