- Circadian rhythm and melatonin
- Sleep and Wakefulness Research
- Amino Acid Enzymes and Metabolism
- Regulation of Appetite and Obesity
- Neuropeptides and Animal Physiology
- Hormonal and reproductive studies
- Nitric Oxide and Endothelin Effects
- Neuroendocrine regulation and behavior
- Epigenetics and DNA Methylation
- Sleep and related disorders
- Cardiovascular, Neuropeptides, and Oxidative Stress Research
- Hypothalamic control of reproductive hormones
- Neuroscience and Neuropharmacology Research
- Neurobiology and Insect Physiology Research
- Blood properties and coagulation
- Reproductive biology and impacts on aquatic species
- Sperm and Testicular Function
- Nanoparticles: synthesis and applications
- Pharmacological Effects and Assays
- Erythrocyte Function and Pathophysiology
- Animal Behavior and Reproduction
- Amphibian and Reptile Biology
- Moringa oleifera research and applications
- Hormonal Regulation and Hypertension
- Receptor Mechanisms and Signaling
University of Naples Federico II
2011-2025
The ongoing rapid climate change, combined with the disturbance of fish breeding grounds, may impact reproduction by endangering successful and survival, thus affect viable sustainability in aquaculture systems as well sea. In this study we focus on biocomplexity response to change. Further, propose adaptive strategies, including technological advancements, using a noninvasive non-lethal approach, outline an assisted nutrigenomics approach mitigating reproductive risks posed This was done...
In the present study we report occurrence of D-aspartic acid (D-Asp) in ovary green frog Rana esculenta and its putative involvement testosterone production by gonad. ovary, D-Asp concentrations undergo significant variations during main phases sexual cycle. spawning females (March), concentration was low (2.5 +/- 1.1 nmol/g ovary) post-reproductive period (June) it increased reached peak level (58.0 10.1 nmol/g) October. that month, vitellogenesis occurs a new set ovarian follicles...
The present study investigated the role of D-aspartic acid (D-Asp) in ovarian steroidogenesis and its effect on aromatase activity lizard, Podarcis s. sicula. It was determined that D-Asp concentrations vary significantly during phases reproductive cycle: they inversely with testosterone directly oestradiol ovary plasma. Experimental treatment showed administration induces a decrease an increase oestradiol, other amino acids (L-Asp, D-Glu D-Ala) instead has no effects. Experiments vitro...
This study investigated the involvement of D-aspartic acid (D-Asp) in testicular steroidogenesis green frog Rana esculenta and its effect on stimulation thumb pad morphology glandular activity, a typical testosterone-dependent secondary sexual characteristic this amphibian species. In testis, D-Asp concentrations vary significantly during reproductive cycle: they are low pre- post-reproductive periods, but reach peak levels period (140-236 nmol/g wet tissue). Moreover, testis through cycle...
D-Aspartic acid (D-Asp) and nitric oxide (NO) play an important role in tuning testosterone production the gonads of male vertebrates. In particular, D-Asp promotes either synthesis or release testosterone, whereas NO inhibits it. this study, we have investigated for first time birds putative effects on testicular relation to two phases reproductive cycle adult captive wild-strain mallard (Anas platyrhynchos) drake. It is a typical seasonal breeder its consists short period (RP) spring...
Male fertility is strongly affected by the overexpression of free radicals induced heavy metals. The aim this study was to evaluate potential antioxidant, anti-inflammatory, and gonado-protective effects natural compounds. Biochemical morphological assays were performed on male albino rats divided into five groups: a control group (water only), orally exposed metal mixture Pb-Cd-Hg-As alone three groups co-administered an aqueous extract Nigerian medicinal plant, Anonychium africanum...
Orexin A (OxA) is a neuropeptide produced in the lateral hypothalamus that performs pleiotropic functions different tissues, including involvement energy homeostasis and reproductive neuroendocrine functions. The role of OxA particularly important given well-studied relationships between physiological mechanisms controlling balance reproduction. enzyme P450 aromatase (ARO) helps convert androgens to estrogens has roles steroidogenesis, spermatogenesis, metabolism several organs. goal this...
The orexins A (OxA) and B (OxB) are two hypothalamic peptides involved in many physiological functions of the mammalian body. They act through binding G-coupled receptors named receptor 1 (OX1 ) 2 (OX2 for orexins. first is specific OxA, while second binds both substances with equal affinity. relative have been traced by means different techniques also at periphery body particularly adrenals, gastrointestinal genital organs. Aim this work was to investigate presence OxB OX2...
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Cryptorchidism is one of the most common birth disorders male reproductive system identified in dogs and other mammals. This condition characterised by absence (unilateral) or both (bilateral) gonads from scrotum. The peptides orexin A (OxA) B (OxB) were obtained post-transcriptional proteolytic cleavage a precursor molecule, called prepro-orexin. These substances bind two types G-coupled receptors receptor 1 (OX1R) 2 (OX2R) for orexins. OX1R specific to OxA while OX2R binds with equal...
Orexins A (OXA) and B (OXB) the receptors 1 (OX1R) 2 (OX2R) for orexins are hypothalamic peptides found in several mammalian organs participated to control of a wide assortment physiological pathological functions. The distribution OXA OX1R has been extensively studied male gonad mammals. Here, we examined expression localization OXB OX2R as well their possible involvement regulation testicular epididymal functions, healthy cryptorchid dogs, employing some techniques such...