A5070462309- Diet and metabolism studies
- Adipose Tissue and Metabolism
- Adipokines, Inflammation, and Metabolic Diseases
- Nutritional Studies and Diet
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Dietary Effects on Health
- Cardiovascular and exercise physiology
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Muscle metabolism and nutrition
- Obesity, Physical Activity, Diet
- Diet, Metabolism, and Disease
- Liver Disease Diagnosis and Treatment
- Exercise and Physiological Responses
- Cardiovascular Disease and Adiposity
- Asthma and respiratory diseases
- Lipid metabolism and disorders
- Nutrition, Genetics, and Disease
- Fatty Acid Research and Health
- Meningioma and schwannoma management
- Neurofibromatosis and Schwannoma Cases
- Obesity and Health Practices
- Advanced Chemical Sensor Technologies
- Coffee research and impacts
- Sports Performance and Training
- Child Nutrition and Water Access
Oklahoma State University
2017-2025
University of Washington
2004-2025
Neurological Surgery
2024-2025
Oklahoma State University at Tulsa
2024
University of Washington Medical Center
2024
Seattle University
2024
Oklahoma State University Oklahoma City
2019-2023
Albion College
2023
Emerson (United States)
2021-2022
Kansas State University
2014-2021
Normal weight obesity (NWO) is a body composition phenotype that associated with increased cardiometabolic risk and characterized by normal mass index but elevated fat. The purpose of this study was to determine sex differences in aerobic capacity across phenotypes, including lean (NWL), NWO, traditional (OB). We recruited 60 participants according three phenotypes: NWL (n = 10 females, n males), NWO OB males). Measurements included fasting metabolic factors, X-ray scan, peak exercise test...
Abstract Brain metastases (BrM) arising from solid tumors is an ever increasing and often devastating clinical challenge impacting hundreds of thousands patients annually worldwide. As systemic anticancer therapies, thus survival, improve, risk for central nervous system (CNS) recurrence has increased. Historically, with BrM were excluded trials; however, there been a shift towards inclusion over the past decade. To most effectively design next generation trials BrM, multidisciplinary team...
Our study provides novel evidence that young adult women with moderate-to-severe adverse childhood experience (ACE) exposure present impaired endothelial function and lower circulating sirtuin 1 (SIRT1) concentrations than age-matched controls. However, an 8-wk exercise intervention was unable to augment or SIRT1 in a subset of those ACEs. data suggest ACEs-related impairments may be secondary decreased NO bioavailability via and/or oxidative stress-related mechanisms.
Abstract The liver enzyme cytochrome P450 1A2 (CYP1A2) is responsible for 90% of caffeine metabolism, while exerts many its effects via antagonist binding to adenosine A2a receptors (ADORA2A). This study aimed examine whether functional single nucleotide polymorphisms (SNPs) in 1976T > C (ADORA2A; rs5751876) and −163C A (CYP1A2; rs762551) influence the effect on postprandial glucose (GLU) response a carbohydrate meal. We report that individuals with CC, but not CT/TT genotypes display...
This randomized controlled pilot trial shows, for the first time, that 8 wk of structured, progressive exercise training lowers serum endothelin-1 (ET-1) and improves positive psychological coping in young women with significant early-life psychosocial stress. Furthermore, observed associations among changes attributes, ET-1, systolic blood pressure signify a potential interplay between psychology cardiovascular disease risk adverse childhood experiences.
To compare the postprandial metabolic responses to a high-fat meal in healthy adults who differ by age and physical activity level.
Background The transient rise in blood lipids following a high-fat meal (HFM), known as postprandial lipemia, is linked to systemic inflammation and cardiovascular disease, but can be blunted by exercise. However, minimal research has investigated the effects of realistic exercise bouts on lipemia at-risk individuals. purpose this study was assess moderate-intensity aerobic lasting 30 or 60 min performed evening before HFM, overweight, insufficiently active men.Methods In...
We recently reported a high prevalence of expiratory flow limitation (EFL) independent sex in prepubescent children that exceeds the adults. It is unknown how transpubertal maturation and growth affect pulmonary function, specifically EFL, during exercise. The purpose this longitudinal study was to investigate changes including differences, from pre- postpuberty.Twenty-one (age 12-16 yr, 11 boys 10 girls) were recruited 40 who completed testing our laboratory ∼5 yr ago. Subjects function...
Consuming a high-fat meal (HFM) may lead to postprandial lipemia (PPL) and inflammation. Postprandial exercise has been shown effectively attenuate PPL. However, little is known about the impact of on systemic inflammation whether PPL are associated. The purpose this study was determine moderate intensity performed 60 min following true-to-life HFM would Thirty-nine young adults (18–40 year) with no metabolic disease were randomized either control group (CON) who remained sedentary during...
Background Inflammation and angiogenesis are key facets of cardiovascular disease pathophysiology. Age physical activity level can influence fasting systemic inflammation, but the impact these factors on postprandial inflammation is unknown. In addition, markers have never been tested in context a single high-fat meal (HFM).
Background: Postprandial lipemia (PPL) is a cardiovascular disease risk factor. However, the effects of different fat sources on PPL remain unclear. We aimed to determine postprandial response in triglycerides (TG) four dietary adults. Methods: Participants completed randomized meal trials. For each trial, participants (n = 10; 5M/5F) consumed high-fat (HFM) (13 kcal/kg; 61% total kcal from fat) with source derived butter, coconut oil, olive or canola oil. Blood was drawn hourly for 6 h...
We investigated whether an acute bout of moderate intensity exercise in the postprandial period attenuates triglyceride and airway inflammatory response to a high-fat meal (HFM) compared remaining inactive period. Seventeen (11 M/6 F) physically active (≥150 min/week moderate-vigorous physical activity (MVPA)) subjects were randomly assigned (EX; 60%<mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML"...
Household air pollution (HAP) contributes to the global burden of disease. Our primary purpose was determine whether HAP exposure associated with reduced lung function and respiratory non-respiratory symptoms in Belizean adults children. secondary investigate lifestyle (physical activity (PA) fruit vegetable consumption (FV)) is reported symptoms. (n = 67, 19 Male) children 23, 6 from San Ignacio Belize surrounding areas participated this cross-sectional study. Data collection took place at...
Objective This study examined the effects of a peer-led integrated nutrition education intervention with maternal social support using Care Groups on infant growth among South Sudanese refugees in Uganda. Methods A community-based cluster-randomized trial (RCT) was conducted 390 pregnant women (third trimester). Two arms were Mothers-only(n = 131) and Parents-combined (n 142) Control 117). WHO standards defined length-for-age z-scores (LAZ) for stunting, weight-for-age (WAZ) underweight...