A5100428924- Mycorrhizal Fungi and Plant Interactions
- Viral Infections and Vectors
- Vector-borne infectious diseases
- Fungal Biology and Applications
- Vector-Borne Animal Diseases
- Forest Ecology and Biodiversity Studies
- Mast cells and histamine
- Viral gastroenteritis research and epidemiology
- Animal Virus Infections Studies
- Immune Cell Function and Interaction
- Immunotherapy and Immune Responses
- Plant Parasitism and Resistance
- Immune Response and Inflammation
- Immune cells in cancer
- Complement system in diseases
- Gastrointestinal Tumor Research and Treatment
- Animal Disease Management and Epidemiology
- Mosquito-borne diseases and control
- Bioenergy crop production and management
- NF-κB Signaling Pathways
- Plant-Microbe Interactions and Immunity
- Xenotransplantation and immune response
- Acute Lymphoblastic Leukemia research
- Virus-based gene therapy research
- Chronic Myeloid Leukemia Treatments
Chinese Academy of Agricultural Sciences
2020-2025
Lanzhou Veterinary Research Institute
2025
Lanzhou University
2025
University of Chicago
2023-2024
Beijing Red Cross Blood Center
2024
Northwest A&F University
2013-2023
South China Agricultural University
2023
Zhejiang Chinese Medical University
2023
Harbin Veterinary Research Institute
2020
Ministry of Agriculture and Rural Affairs
2018-2019
Abstract Tripartite motif (TRIM) family proteins are important effectors of innate immunity against viral infections. Here we identified TRIM35 as a regulator TRAF3 activation. Deficiency in or inhibition suppressed the production type I interferon (IFN) response to infection. Trim35 -deficient mice were more susceptible influenza A virus (IAV) infection than wild-type mice. promoted RIG-I-mediated signaling by catalyzing Lys63-linked polyubiquitination and subsequent formation complex with...
Spotted fever group (SFG) rickettsiae are important causative agents of (re)emerging tick-borne infectious diseases in humans, and ticks play a key role their maintenance transmission. In this study, hard were collected from five sampling sites North China 2017 2018. Of them, Haemaphysalis longicornis, Rhipicephalus microplus Dermacentor nuttalli livestock (sheep goats) the vegetation, Hyalomma asiaticum sheep, goats camels, marginatum sheep goats. The SFG identified these by amplifying...
In China, thirteen species of tick-borne rickettsiales bacteria pathogenic to human have been reported in ticks and host animals, patients caused by them also has identified. However, investigation for circulating Xi'an wasn't performed although diseases resembling these organisms found. this study, domestic animals Xi'an, were tested the presence humans. Besides A. ovis, a high prevalence capra was observed suggesting public health risk exists. addition, two novel Anaplasma closely related...
Four species within Anaplasma genus are emerging zoonotic pathogens, which transmitted by ticks and generate veterinary public health concerns. Here, we performed a molecular survey of in Ankang, Northwest China.Hard were collected identified using morphological methods. Human-pathogenic tested nested polymerase chain reaction. The nearly complete rrs, gltA, groEL genes sequences from revealed amplified sequenced to determine their characteristics phylogeny.All Ankang belonged the...
Casuarina glauca is an important coastal protection forest species, which exposed to high salt stress all year round. Arbuscular mycorrhizal fungi (AMF) can promote the growth and tolerance of C. under stress. However, effects AMF on distribution Na+ Cl- expression related genes in need be further explored. This study explored Rhizophagus irregularis plant biomass, Cl-, NaCl through pot simulation experiments. The results revealed that mechanisms transport were different. took a accumulation...
The current paradigm indicates that naive T cells are primed in secondary lymphoid organs. Here, we present evidence intranasal administration of peptide antigens appended to nanofibers primes CD8+ the lung independently and prior priming draining mediastinal lymph node (MLN). Notably, comparable accumulation transcriptomic responses MLN observed both Batf3KO wild-type (WT) mice, indicating that, while cDC1 dendritic (DCs) major subset for cross-presentation, cDC2 DCs alone capable...
Gonocytes are important for the study of spermatogenesis. Identification and isolation gonocytes has been reported in rodents but not pigs due to a lack molecular markers gonocytes. The objective this was identify THY1 expression porcine testicular tissue subsequently utilise as marker isolate enrich from testes newborn piglets. Immunohistochemical analysis showed that expressed Double-immunofluorescent ZBTB16 indicated were partially co-localised both GATA4 suggested THY1(+) cells Sertoli...
Saline-alkali stress seriously endangers the normal growth of Populus simonii×P. nigra. Arbuscular mycorrhizal (AM) fungi can enhance saline-alkali tolerance plants by establishing a symbiotic relationship with them. In this study, pot experiment was conducted to simulate environment where nigra were inoculated Funneliformis mosseae explore their effects on Our results show that total 8 NHX gene family members are identified in F. regulate distribution Na+ inducing expression PxNHXs. The pH...
The aim of the present study was to investigate influence stimulating food (SF), a Traditional Chinese Medicine term for high protein, fat diet, on psoriasis exacerbation. It hypothesized that SF disposed psoriasis-like aggravation might be related inflammatory pathways induction via gut dysbiosis. In study, mice were fed either an or normal diet 4 weeks. last week, their back hair removed establish dermatitis by imiquimod. After sacrifice, blood samples, alimentary tissues and skin lesions...
The establishment of a platelet-apheresis donor database may provide feasible solution to improve the efficacy platelet transfusion in patients with immune refractoriness (PTR). This study aimed establish HLA genotype Suzhou, HLA-I compatible platelets for PTR ensure safety and effectiveness transfusions. We used polymerase chain reaction sequence-based typing (PCR-SBT) method by performing high-resolution HLA-A, -B, -C genotyping on 900 donors. antibody was detected using Luminex device,...
This study explored the specific molecular mechanism of Laccaria bicolor to help Populus trichocarpa resist infection by Botryosphaeria dothidea.Transcriptome technology was used sequence P. under disease stress, and a total 6379 differentially expressed genes (DEGs) were identified. A 536 new DEGs induced L. during B. dothidea. helps prevent alleviate dothidea regulating related in cell wall pathway, signal transduction disease-resistant protein synthesis pathway antioxidant enzyme...
Poplars can be harmed by poplar canker. Inoculation with mycorrhizal fungi improve the resistance of poplars to canker, but molecular mechanism is still unclear. In this study, an aseptic inoculation system L. bicolor-P. trichocarpa-B. dothidea was constructed, and transcriptome analysis performed investigate regulation bicolor expression genes in roots P. trichocarpa during onset B. infection, a total 3022 differentially expressed (DEGs) were identified. Weighted correlation network (WGCNA)...
Abstract Background: Arbuscular mycorrhizal fungi (AMF) form a symbiotic relationship with host plants, which can promote plants to absorb more water and nutrients, thus improve the stress resistance of plants. Our study aimed investigate effects Rhizophagus irregularis on Populus simonii × P. nigra seedlings under drought stress. Results: The experiment was completely random design two conditions (well-watered or stress) AMF treatments (inoculated without R. ). results showed that performed...