A5083902415- Porphyrin and Phthalocyanine Chemistry
- Skin Protection and Aging
- Metabolomics and Mass Spectrometry Studies
- Inhalation and Respiratory Drug Delivery
- Advanced Proteomics Techniques and Applications
- Lipid Membrane Structure and Behavior
- Conducting polymers and applications
- Advancements in Transdermal Drug Delivery
- Glycosylation and Glycoproteins Research
- Molecular Junctions and Nanostructures
- Polymer Surface Interaction Studies
- Advanced Drug Delivery Systems
- Luminescence and Fluorescent Materials
- Bee Products Chemical Analysis
- Surface Chemistry and Catalysis
- Cholesterol and Lipid Metabolism
- HIV Research and Treatment
Luxembourg Institute of Science and Technology
2018-2022
Despite being a critical molecule in the brain, mass spectrometry imaging (MSI) of cholesterol has been under-reported compared to other lipids due difficulty ionizing sterol molecule. In present work, we have employed an on-tissue enzyme-assisted derivatization strategy improve detection brain tissue sections. We report distribution and levels across specific structures mouse model Niemann-Pick type C1 disease, during development. MSI revealed that adult mouse, is highest pons medulla how...
While the solution‐phase synthesis of directly fused porphyrin tapes has been successfully developed in recent years, deposition these promising compounds thin film form remained a challenge. In this study, we report simultaneous and conductive poly(porphyrin) coatings based on substrate independent up‐scalable oxidative chemical vapor (oCVD) approach. A particular emphasis is given to selection sublimation conditions oxidant. The direct fusion nickel(II) 5,15‐(diphenyl)porphyrin (NiDPP)...
Coatings consisting in gentamicin-containing nanocapsules have been synthetized by means of an aerosol-assisted atmospheric pressure plasma deposition process. The influence different parameters affecting the process has extensively investigated a morphological and chemical characterization coatings. Scanning electron microscopy highlighted presence whose size abundance depend on power input time. A detailed analysis carried out with matrix-assisted laser desorption ionization coupled to...
Porous and highly conjugated multiply fused porphyrin thin films are prepared from a fast single-step chemical vapor deposition approach. While the solution-based coupling of porphyrins is usually undertaken at room temperature, gas phase reaction nickel(II) 5,15-(diphenyl)porphyrin iron(III) chloride (FeCl
Sunscreens must now be effective in protecting skin from ultraviolet, as well visible/infrared radiation. Here, TriAsorB, a new broad-spectrum sun filter, was formulated with three other sunscreens and their distribution on human studied using standard penetration protocol two novel mass spectrometry imaging techniques: atmospheric pressure matrix assisted laser desorption ionization (AP-MALDI) coupled to high resolution time of flight - secondary ion (ToF-SIMS). The showed that filters...
Summary Despite being a critical molecule for neurobiology and brain health, mass spectrometry imaging (MSI) of cholesterol has been under reported compared to other lipids, due the difficulty in ionising sterol molecule. In present work we have employed an on-tissue enzyme-assisted derivatisation strategy improve detection tissue sections. We report distribution levels across specific structures mouse brain, model Niemann-Pick type C1 (NPC1) disease, during development. MSI revealed how...