A5033145844- BRCA gene mutations in cancer
- Ovarian cancer diagnosis and treatment
- CRISPR and Genetic Engineering
- Reproductive tract infections research
- Reproductive Health and Contraception
- Muscle Physiology and Disorders
- Molecular Biology Techniques and Applications
- Maternal and fetal healthcare
- RNA regulation and disease
- Cancer Genomics and Diagnostics
- RNA and protein synthesis mechanisms
- PARP inhibition in cancer therapy
- Uterine Myomas and Treatments
- Menstrual Health and Disorders
- Spine and Intervertebral Disc Pathology
- Assisted Reproductive Technology and Twin Pregnancy
- Blood groups and transfusion
- Advanced biosensing and bioanalysis techniques
- Erythrocyte Function and Pathophysiology
- Genetics, Bioinformatics, and Biomedical Research
- Maternal and Perinatal Health Interventions
- DNA Repair Mechanisms
- Attention Deficit Hyperactivity Disorder
- Testicular diseases and treatments
- Endometriosis Research and Treatment
Ospedale San Giacomo Apostolo
2020
Università Cattolica del Sacro Cuore
2017-2018
Istituti di Ricovero e Cura a Carattere Scientifico
1998-2018
Agostino Gemelli University Polyclinic
2018
University of the Sacred Heart
2017
IRCCS Materno Infantile Burlo Garofolo
2015
University of Trieste
2012-2014
Casa Sollievo della Sofferenza
1998
Institute of Cell Biology and Neurobiology
1995-1997
University of Padua
1994
To evaluate the efficacy of an association N‐acetyl cystein, alpha‐lipoic acid, and bromelain (NAC/LA/Br) in treatment endometriosis we set up a new vivo murine model. We explored anti‐inflammatory proapoptotic effect this combination on human endometriotic endothelial cells (EECs) isolated from normal uterus (UtMECs). implanted fragments cysts intraperitoneally into SCID mice to NAC/LA/Br treatment. UtMECs EECs, untreated or treated with NAC/LA/Br, were activated proinflammatory stimulus...
The authors report on a retrospective analysis of 81 patients undergoing laminectomy for the clinico-radiological diagnosis lumbar stenosis. One hundred and eighty-five variables were considered computer system was used in their evaluation. most frequent site involvement at L4-5. Follow-up time ranged from 3 months to 12 years. 95% good results obtained, re-operation rate 7%. complication 11%. There no mortality. No significant correlation between factors investigated outcome found. This is...
We report a patient with large intragenic dystrophin deletion of exons 17-51 inclusive associated congenital cataract and mild Becker muscular dystrophy. The was similar to the described in <i>mdx</i> mouse. loss 68% rod domain including hinge 2 3 regions did not adversely affect correct localization association dystrophin-associated glycoprotein complex. This observation may have implications for minigenes suitable gene therapy.
Estroprogestins with "natural oestrogen" has represented a new option in terms of combined hormonal contraception. So, the aim this study is to investigate how estroprogestins natural estrogen may modify vaginal niche. In literature, very few studies focused on interaction between contraception and milieu. This prospective comparative study. We enrolled 60 women from January 2013 September 2013, 30 them were administered estradiol valerate dienogest (E2V+DNG – Klaira®) quadriphasic regimen,...
The aim of the study was to evaluate prognostic value human epididymis protein 4 (HE4) and cancer antigen 125 markers with pathological factor complete preoperative clinical panel help treatment planning.This prospective multicenter conducted in 2 gynecologic oncology centers between 2012 2014 (Institute for Maternal Child Health IRCCS Burlo Garofolo Trieste Catholic University Sacred Heart Rome, Italy). We enrolled 153 patients diagnosed early (International Federation Gynecology Obstetrics...
Objective Trial of labor after cesarean delivery (TOLAC) is a common practice worldwide but the evidence still scant regarding this in women who underwent 2 previous cesareans. The purpose study to retrospectively review our experience with vaginal birth two sections (VBA2C), specific attention indications for and women's motivation attempting trial labor. Study Design This was retrospective cohort conducted primary care hospital between January 2011 December 2019. Inclusion criteria were:...
In a 72-year-old woman with no associated personal or family history of breast and/or ovarian cancers, we identified novel somatic pathogenic BRCA2 variant (c.18_28delAGAGAGGCCAA, p.Lys6Asnfs*4) using next-generation sequencing (NGS). The allele frequency (VAF) was 16%, and Sanger unable to identify this variant. Adopting high-resolution melting analysis strategy coupled NGS, successfully highlighted the presence c.18_28delAGAGAGGCCAA allele.
β-thalassemia mutations were characterized in a sample of 70 patients from United Arab Emirates (U.A.E.), resulting an enlargement the spectrum types found country. The complete association between most common IVS I nt 5 (G-C) mutation and specific haplotype reveals independent origin this U.A.E. © 1995 Wiley-Liss, Inc.
A 33-year old woman with a massive uterine bleeding occurred after LPS treated rupture due to miomectomy scar pregnancy. US revealed an anechoic intramiometrial lesion surrounded by multiple tubular lesions distributed in the myometrium. 2D and Colour Doppler sonography central arterial-like turbulent, low impedance blood flow inside lesion. The hypothesis was of artery pseudoaneusysm coexisting AV malformation. 3DTVUS performed evaluate exact position its angioarchitecture. HD-flow 3D...