- Endometriosis Research and Treatment
- Reproductive System and Pregnancy
- Uterine Myomas and Treatments
- Reproductive Biology and Fertility
- Sperm and Testicular Function
- Pelvic floor disorders treatments
- Gynecological conditions and treatments
- Pregnancy and preeclampsia studies
- Ectopic Pregnancy Diagnosis and Management
- Endometrial and Cervical Cancer Treatments
- Ovarian cancer diagnosis and treatment
- Diabetes Treatment and Management
- Maternal and fetal healthcare
- COVID-19 Impact on Reproduction
- Ovarian function and disorders
- Gestational Trophoblastic Disease Studies
- Reproductive tract infections research
- Assisted Reproductive Technology and Twin Pregnancy
- Pelvic and Acetabular Injuries
- Reproductive Health and Technologies
- Pregnancy-related medical research
- Extracellular vesicles in disease
- Complement system in diseases
- Cellular Mechanics and Interactions
- Coagulation, Bradykinin, Polyphosphates, and Angioedema
University of Trieste
2016-2025
IRCCS Materno Infantile Burlo Garofolo
2016-2025
Istituti di Ricovero e Cura a Carattere Scientifico
2019-2025
Università di Camerino
2025
Ospedale di Cattinara
2015-2024
Università Cattolica del Sacro Cuore
2024
Sapienza University of Rome
2022
Bambino Gesù Children's Hospital
2021-2022
Consorzio Nazionale Interuniversitario per le Telecomunicazioni
2022
Santobono Children's Hospital
2018-2022
Despite being quite frequent and having serious implications in terms of symptomatology fertility, data on incidence prevalence endometriosis adenomyosis following gold standard definitions are dramatically lacking. The average time from onset symptoms to diagnosis industrialized countries still ranges five ten years. Using the regional centralized linkage system, we calculated female population Friuli Venezia Giulia region, Italy, for years 2011–2013. Cases were defined as new diagnoses...
Regarding bacterial vaginosis (BV), the relevance of vaginal microbiota to women's health fulfils a key role but knowledge gaps regarding aerobic vaginitis (AV) exist. This study aims characterize microbiome and its relationship with local immune mediators providing an opportunity define link between commensal microorganisms opportunistic pathogens in relation given community state type (CST). A total 90 samples from Caucasian asymptomatic women reproductive age (18y–40y) attending yearly...
We address adaptive detection of coherent signals backscattered by possible point-like targets or originated from electronic countermeasure (ECM) systems in presence thermal noise, clutter, and noise-like interferers. In order to come up with a class decision schemes capable discriminating between ECM signals, we resort generalized likelihood ratio test (GLRT) implementations Neyman-Pearson rule (i.e., for multiple hypotheses). The detectors rely on secondary data, free signal components,...
Biomarkers have a wide application in research and clinic, they help to choose the correct treatment for diseases. Recent studies, addressing vaginal microbiome using next generation sequencing (NGS), reported involvement of bacterial species infertility. We compared idiopathic infertile women with that healthy, including vaginosis affected non‐idiopathic women, identify suitable as biomarkers. Information on microorganisms was obtained from V3‐16S rDNA cervical–vaginal fluids 96 Ion Torrent...
C1q is the first subcomponent of classical pathway complement system and belongs to C1q/Tumour Necrosis Factor superfamily. In addition, can perform a diverse range immune non-immune functions in complement-dependent as well -independent manner. Being charge pattern recognition molecule innate immunity, recognise number self, non-self altered-self ligands bring about effector mechanisms designed clear pathogens via opsonisation inflammatory response. locally synthesised by macrophages...
Apoptosis plays an important role in regulating spermatogenesis. However, the biological significance of apoptosis ejaculated sperm is not yet clear. This study set out to investigate how correlates with semen quality and presence seminal leukocytes.Fifty-seven samples from male partners infertile couples were classified as normal or abnormal according World Health Organization guidelines. Flow cytometry was used evaluate populations leukocytes. Preliminary flow analysis using...
In the present paper, we focus on design of adaptive decision schemes for point-like targets; proposed algorithms can take advantage possible spillover target energy between consecutive matched filter samples. To this end, assume that received useful signal is known up to a complex factor modeled as deterministic parameter; moreover, it embedded in correlated Gaussian noise with unknown covariance matrix. Finally, estimation purposes set secondary data, free components, but sharing same...
Journal Article Investigating the mechanical properties of zona pellucida whole human oocytes by atomic force spectroscopy Get access Laura Andolfi, Andolfi Istituto Officina dei Materiali-CNR, Basovizza, 34149 Trieste, Italy E-mail: andolfi@iom.cnr.it Search for other works this author on: Oxford Academic Google Scholar Elena Masiero, Masiero Department Medicine, Surgery and Health Sciences, University Giolo, Giolo Institute Maternal Child Health, IRCCS Burlo Garofolo, Monica Martinelli,...
Coronavirus disease 2019 (COVID-19) caused by the severe acute respiratory syndrome–coronavirus 2 (SARS-CoV-2) is a global pandemic, affecting mostly system. Understandably, attention also being directed towards urogenital tract. In this work, expression patterns of various host molecules possibly involved in viral entry and replication were investigated human female male reproductive systems inquiring online repositories, including Human Protein Atlas, GTEx, FANTOM5. Our findings highlight...
Infertile couples undergoing the use of assisted reproductive technology are a good study model to evaluate microbiological signatures affecting health. We tested vaginal lavages, follicular fluids, embryo culture mediums, and seminal fluids from 47 for their microbiome composition HPV infection. Twenty-five infertile were diagnosed with unexplained infertility, whereas 22 explained infertility. Lactobacilli dominant in lavages both patient groups, most abundant species was L. iners (CST...
Background and objectives: Cervical pregnancy (CP) is a rare form of ectopic (EP) in which the embryo implants grows inside endocervical canal. Early diagnosis essential order to allow conservative medical surgical treatments. Although many treatment approaches are disponible, most effective still unclear. The aim this study evaluate efficacy hysteroscopic management early CP preserve future fertility. Materials Methods: This retrospective observational case series. Five patients with CP,...
Photodynamic therapy (PDT) is a potential synergistic approach to chemotherapy for treating ovarian cancer, the most lethal gynecologic malignancy. Here we used M13 bacteriophage as targeted vector efficient photodynamic killing of SKOV3 and COV362 cells. The phage was refactored (M13r) display an EGFR binding peptide in its tip that frequently overexpressed cancer. conjugated with chlorin e6 (Ce6), one widely photosensitizers (M13r-Ce6). new platform, upon irradiation, generated ROS by type...