A5005529168- Glioma Diagnosis and Treatment
- Advanced Neuroimaging Techniques and Applications
- Meningioma and schwannoma management
- Brain Metastases and Treatment
- Advanced MRI Techniques and Applications
- MRI in cancer diagnosis
- Radiomics and Machine Learning in Medical Imaging
- Functional Brain Connectivity Studies
- Fetal and Pediatric Neurological Disorders
- Acute Ischemic Stroke Management
- Ear Surgery and Otitis Media
- Cerebral Venous Sinus Thrombosis
- Vascular Malformations Diagnosis and Treatment
- Intracranial Aneurysms: Treatment and Complications
- Cerebrovascular and Carotid Artery Diseases
- Peripheral Nerve Disorders
- Infectious Encephalopathies and Encephalitis
- Head and Neck Surgical Oncology
- Ear and Head Tumors
- Spinal Dysraphism and Malformations
- Medical Imaging Techniques and Applications
- Moyamoya disease diagnosis and treatment
- Migraine and Headache Studies
- Brain Tumor Detection and Classification
- Down syndrome and intellectual disability research
Sapienza University of Rome
2015-2025
Azienda Ospedaliera Sant'Andrea
2015-2025
University of Pittsburgh
2024
Ospedale di Cattinara
2024
Tanta University
2024
Fondazione Toscana Gabriele Monasterio
2021
Hudson Institute
2020
John Wiley & Sons (United States)
2020
Policlinico Umberto I
2015-2019
University of Trieste
2019
to investigate the factors affecting survival and toxicity in patients treated with stereotactic radiosurgery (SRS), special attention volumes of brain receiving a specific dose (V10 - V16 Gy) as predictors for radionecrosis.Two hundred six consecutive 310 cerebral metastases less than 3.5 cm were SRS primary treatment followed prospectively at University Rome La Sapienza Sant'Andrea Hospital. Overall survival, control, local control estimated using Kaplan-Meier method calculated from time...
Pituitary apoplexy (PA) is a rare and potentially fatal clinical condition presenting acute headache, vomiting, visual impairment, ophthalmoplegia, altered mental state possible panhypopituitarism. It mostly occurs in patients with haemorrhagic infarction of the pituitary gland due to pre-existing macroadenoma. Although there are pathological physiological conditions that may share similar imaging characteristics, both features can guide radiologist towards correct diagnosis, especially...
C1q is the first subcomponent of classical pathway complement system and belongs to C1q/Tumour Necrosis Factor superfamily. In addition, can perform a diverse range immune non-immune functions in complement-dependent as well -independent manner. Being charge pattern recognition molecule innate immunity, recognise number self, non-self altered-self ligands bring about effector mechanisms designed clear pathogens via opsonisation inflammatory response. locally synthesised by macrophages...
Isocitrate dehydrogenase (IDH) mutant and wildtype glioblastoma multiforme (GBM) often show overlapping features on magnetic resonance imaging (MRI), representing a diagnostic challenge. Deep learning showed promising results for IDH identification in mixed low/high grade glioma populations; however, GBM-specific model is still lacking the literature. Our aim was to develop GBM-tailored deep-learning prediction by applying convoluted neural networks (CNN) multiparametric MRI. We selected 100...
Acute disseminated encephalomyelitis (ADEM) is an inflammatory demyelinating disease of the central nervous system (CNS), clinically defined by acute polyfocal neurological syndrome usually with monophasic course. ADEM often occurs after infections, but 5%–10% cases are preceded vaccinations. Several have been described severe respiratory coronavirus 2 (SARS-CoV-2) infection, whereas no case has reported adenovirus-vectored or mRNA COVID-19 vaccine administration. Here we describe a...
To evaluate the association between cardiorespiratory fitness (CRF) and cognition in a large sample of older adults, to examine clinical demographic factors that might moderate these associations.
Brain involvement in myotonic dystrophy type 1 (DM1) is characterised by cortical atrophy and white matter lesions. We compared the magnetic resonance imaging derived grey maps of 22 DM1 patients with those matched, healthy controls using voxel based morphometry to evaluate extension global regional DM1, as well its relationships clinical genetic features. Patients had significantly reduced brain tissue volumes. Grey volume was inversely correlated age; this inverse correlation stronger than...
Radiomic models outperform clinical data for outcome prediction in high-grade gliomas (HGG). However, lack of parameter standardization limits applications. Many machine learning (ML) radiomic employ single classifiers rather than ensemble learning, which is known to boost performance, and comparative analyses are lacking the literature. We aimed compare ML predict clinically relevant tasks HGG: overall survival (OS), isocitrate dehydrogenase (IDH) mutation,...
Abstract Malignant diseases are characterized by a critical trait known as invasiveness, where tumor cells tend to spread from the primary tissue layer into surrounding healthy tissues and distant organs. Presently, histopathology offers essential insights for diagnosing, classifying, predicting outcomes, guiding patient-specific treatments. However, histology two-dimensional data chosen cutting planes. Although 3D histological volumes can be generated through serial sectioning or whole...
Magnetic resonance with diffusion tensor image (DTI) may be able to estimate trajectories compatible subcortical tracts close brain lesions. A limit of DTI is shifting (movement the after dural opening and tumor resection).To calculate shift corticospinal tract (CST) in patients undergoing glioma resection predict directions CST.DTI was acquired 20 carried out through 12 noncollinear directions. Dedicated software "merged" all sequences tractographic processing whole dataset sent...