A5074399091- Glioma Diagnosis and Treatment
- Cerebrovascular and Carotid Artery Diseases
- Advanced MRI Techniques and Applications
- Advanced Neuroimaging Techniques and Applications
- Meningioma and schwannoma management
- Brain Metastases and Treatment
- Intracranial Aneurysms: Treatment and Complications
- Acute Ischemic Stroke Management
- Functional Brain Connectivity Studies
- MRI in cancer diagnosis
- Vascular Malformations Diagnosis and Treatment
- Spinal Dysraphism and Malformations
- Multiple Sclerosis Research Studies
- Radiomics and Machine Learning in Medical Imaging
- Fetal and Pediatric Neurological Disorders
- Pituitary Gland Disorders and Treatments
- Spine and Intervertebral Disc Pathology
- Cerebrospinal fluid and hydrocephalus
- Polyomavirus and related diseases
- Growth Hormone and Insulin-like Growth Factors
- Cerebral Venous Sinus Thrombosis
- Neurological Complications and Syndromes
- Adrenal and Paraganglionic Tumors
- Infectious Encephalopathies and Encephalitis
- Epilepsy research and treatment
Sapienza University of Rome
2016-2025
Azienda Ospedaliera Sant'Andrea
2016-2025
Tanta University
2024
Istituto Neurologico Mediterraneo
2020
European Society of Anaesthesiology
2019
University of Rome Tor Vergata
1997-2015
Policlinico Tor Vergata
2003-2015
Policlinico Umberto I
2015
CTO Andrea Alesini
2005-2014
Società Italiana di Cardiologia Interventistica
2013
to investigate the factors affecting survival and toxicity in patients treated with stereotactic radiosurgery (SRS), special attention volumes of brain receiving a specific dose (V10 - V16 Gy) as predictors for radionecrosis.Two hundred six consecutive 310 cerebral metastases less than 3.5 cm were SRS primary treatment followed prospectively at University Rome La Sapienza Sant'Andrea Hospital. Overall survival, control, local control estimated using Kaplan-Meier method calculated from time...
The aim of this study was to evaluate the evolution lumbar disk herniation in patients treated without surgery. Sixty-nine with a proved at magnetic resonance (MR) imaging underwent follow-up MR study. herniations evaluated during both examinations were measured and classified into four categories according change size that occurred. also divided three clinical classes on basis outcome. Sixty-three percent showed reduction more than 30% (48% had 70%), while only 8% demonstrated worsening...
We angiographically studied 80 patients within 6 hours after the onset of ischemic supratentorial infarction. From this group we selected 36 with middle cerebral artery occlusion who survived. In these patients, compared presence a collateral blood supply during early phase extent final parenchymal brain damage obtained by computed tomography 3 months event. The circulation first few stroke reduced size in stem-trunk occlusion. was more efficient had no significant stenosing lesions...
Abstract Cortical gray matter volume and resting state cortical electroencephalographic rhythms are typically abnormal in subjects with amnesic mild cognitive impairment (MCI) Alzheimer's disease (AD). Here we tested the hypothesis that MCI AD subjects, abnormalities of EEG a functional reflection atrophy across disease. Eyes‐closed data were recorded 57 healthy elderly (Nold), 102 MCI, 108 patients. was indexed by magnetic resonance imaging according to neuroimaging initiative project (...
<h3>Purpose</h3> To investigate the efficacy and safety of concurrent stereotactic radiosurgery (SRS) ipilimumab or nivolumab in patients with untreated melanoma brain metastases. <h3>Patients Methods</h3> Eighty consecutive 326 metastases receiving SRS combination were identified from an institutional database retrospectively evaluated. Patients started systemic treatment intravenous within one week SRS. Nivolumab was given at doses 3 mg/kg every two weeks. Ipilimumab administered up to...
Background and purposeFor skull base tumors, target definition is the key to safe high-dose treatments because surrounding normal tissues are very sensitive radiation. In present work we established a joint ESTRO ACROP guideline for volume of tumors.Material methodsA comprehensive literature search was conducted in PubMed using various combinations following medical subjects headings (MeSH) free-text words: "radiation therapy" or "stereotactic radiosurgery" "proton "particle beam "skull...
Prolactinomas are the most frequent pituitary adenomas. Prolactinoma may occur in different clinical settings and always require an individually tailored approach. This is reason why a panel of Italian neuroendocrine experts was charged with task to provide indications for diagnostic therapeutic approaches that can be easily applied contexts. The document provides 15 recommendations diagnosis 54 treatment, issued according GRADE system. level agreement among members formally evaluated by...
Object Areas of intramedullary signal intensity changes (hypointensity on T1-weighted magnetic resonance [MR] images and hyperintensity T2-weighted MR images) in patients with cervical spondylotic myelopathy (CSM) have been described by several investigators. The role postoperative evolution these alterations is still not well known. Methods A total 47 underwent imaging before at the end surgical procedure (intraoperative [iMRI]) for spine decompression fusion using an anterior approach....
Pituitary apoplexy (PA) is a rare and potentially fatal clinical condition presenting acute headache, vomiting, visual impairment, ophthalmoplegia, altered mental state possible panhypopituitarism. It mostly occurs in patients with haemorrhagic infarction of the pituitary gland due to pre-existing macroadenoma. Although there are pathological physiological conditions that may share similar imaging characteristics, both features can guide radiologist towards correct diagnosis, especially...
Isocitrate dehydrogenase (IDH) mutant and wildtype glioblastoma multiforme (GBM) often show overlapping features on magnetic resonance imaging (MRI), representing a diagnostic challenge. Deep learning showed promising results for IDH identification in mixed low/high grade glioma populations; however, GBM-specific model is still lacking the literature. Our aim was to develop GBM-tailored deep-learning prediction by applying convoluted neural networks (CNN) multiparametric MRI. We selected 100...