A5077089777- Meningioma and schwannoma management
- Pituitary Gland Disorders and Treatments
- Head and Neck Surgical Oncology
- Spinal Fractures and Fixation Techniques
- Glioma Diagnosis and Treatment
- Trigeminal Neuralgia and Treatments
- Cerebrospinal fluid and hydrocephalus
- Adrenal and Paraganglionic Tumors
- Surgical Simulation and Training
- Neurofibromatosis and Schwannoma Cases
- Growth Hormone and Insulin-like Growth Factors
- Spine and Intervertebral Disc Pathology
- Ophthalmology and Eye Disorders
- Cerebral Venous Sinus Thrombosis
- Radiomics and Machine Learning in Medical Imaging
- Bone Tumor Diagnosis and Treatments
- Medical Imaging Techniques and Applications
- Scoliosis diagnosis and treatment
- Medical Imaging and Analysis
- Traumatic Brain Injury and Neurovascular Disturbances
- Cardiac, Anesthesia and Surgical Outcomes
- Spinal Dysraphism and Malformations
- Intracranial Aneurysms: Treatment and Complications
- Musculoskeletal pain and rehabilitation
- Iron Metabolism and Disorders
Ospedale regionale di Lugano
2023-2024
Humanitas University
2014-2024
Istituti di Ricovero e Cura a Carattere Scientifico
2020-2024
Technical University of Munich
2023
Laboratory for Biomedical Neurosciences
2023
IRCCS Humanitas Research Hospital
2017-2023
Ente Ospedaliero Cantonale
2023
Fondazione Humanitas per la Ricerca
2015-2016
Azienda Socio Sanitaria Territoriale degli Spedali Civili di Brescia
2010
University of Brescia
2010
Prolactinomas are the most frequent pituitary adenomas. Prolactinoma may occur in different clinical settings and always require an individually tailored approach. This is reason why a panel of Italian neuroendocrine experts was charged with task to provide indications for diagnostic therapeutic approaches that can be easily applied contexts. The document provides 15 recommendations diagnosis 54 treatment, issued according GRADE system. level agreement among members formally evaluated by...
OBJECTIVE In the last 2 decades, endoscopic endonasal approach in treatment of clival chordomas has evolved to be a viable strategy achieve maximal safe resection this tumor. Here, authors present multicentric national study, intending analyze evolution over 20-year time frame and its contribution chordomas. METHODS Clival chordoma cases surgically treated between 1999 2018 at 10 Italian neurosurgical departments were included retrospective study. Clinical, radiological, surgical findings,...
Purpose: To evaluate factors influencing clinical and radiological outcome of extended endoscopic endonasal transtuberculum/transplanum approach (EEA-TTP) for giant pituitary adenomas (GPAs). Methods: We recruited prospectively all consecutive GPAs patients undergoing EEA-TTP between 2015 2019 in 5 neurosurgical centers. Preoperative radiologic features, visual hormonal outcomes, extent resection (EoR), complications recurrence rates were recorded analyzed. Results: Of 1169 treated adenoma,...
<b><i>Introduction:</i></b> Available data on pituitary incidentalomas mostly derive from small-scale studies, with heterogeneous inclusion criteria and limited follow-up. No paper has focused specifically clinically nonfunctioning incidentalomas (CNFPIs). <b><i>Objective:</i></b> To describe the characteristics natural history of patients diagnosed CNFPIs. <b><i>Methods:</i></b> Retrospective multicenter cohort study...
Acromegaly is commonly complicated by arthropathy and skeletal fragility with high risk of vertebral fractures (VFs).This study aimed to assess whether VFs may be associated sagittal spine deformities, arthropathy, impaired quality life (QoL), pain, disability.Thirty-eight patients acromegaly (median age: 55 years, 20 males) 38 matched control subjects were evaluated a low-dose coronal planes, X-ray imaging system (EOS®-2D/3D) for morphometric VFs, radiological signs deformities (Cobb...
Object Due to technological advances in neuroradiology recent years, incidental diagnoses of vestibular schwannomas (VSs) have increased. The aim this study was evaluate the hearing function after treatment with Gamma Knife surgery (GKS) for VSs patients adequately selected “good” or “useful” before and assess possible predictive factors preservation. Methods Of all treated authors' hospital between 2001 2007, they retrospectively studied 50 a unilateral VS whom there serviceable...
BACKGROUND: Image-guided navigation systems (IGS) grant excellent clinical and radiological results, minimizing risks correlated with spinal instrumentation. However, there is some concern regarding the real need for IGS its indications. OBJECTIVE: To analyze accuracy, technical aspect, radiation exposure data of principal based on computed tomography (CT) imaging. METHODS: The all patients treated instrumentation aid an system from January 2003 to March 2013 were retrospectively analyzed....
We investigated the potential of antibody-vectorialized superparamagnetic iron oxide (SPIO) particles as cellular specific magnetic resonance contrast agents to image lymphocyte populations within central nervous system (CNS), with final goal obtaining a reliable tool for noninvasively detecting and tracking in vivo. used bound monoclonal antibody. The particle is agent, by means its T₂* relaxation properties; antibody targeting vector, responsible homing target surface antigen. To...
Intracranial aneurysms occur in 3%-5% of the general population. While precise biological mechanisms underlying formation, growth, and sudden rupture intracranial remain partially unknown, recent research has shed light on potential role inflammation aneurysm development rupture. In addition, there are ongoing investigations exploring feasibility employing new drug therapies for controlling risk factors associated with aneurysms. CD68, a glycosylated glycoprotein human homolog macrosialin,...
Objective: Among the already difficult management of neuro-oncological patients, elderly population remains vulnerable. Because pathology and comorbidities, they present a significantly higher rate medical issues related to surgical management. Despite this, option, if feasible, gold standard in these an Enhanced Recovery After Surgery (ERAS) protocol could improve postoperative safety patients. With this purpose, we prepared study with aim defining hospital length stay (LOS), but also...
(1) Background: We investigated the role of [11C]-methionine PET in a cohort newly diagnosed glioblastoma multiforme (GBM) patients to evaluate whether it could modify extent surgical resection and improve radiation therapy volume delineation. (2) Methods: Newly GBM patients, ages 18-70, with Karnofsky performance scale (KPS) ≥ 70 available MRI were included. Patients treated different amounts followed by radio-chemotherapy. The RT planning was analyzed. A threshold SUVmax searched. (3)...