A5013765993- Diabetes Treatment and Management
- Diabetes and associated disorders
- Diet and metabolism studies
- Autoimmune Bullous Skin Diseases
- Hyperglycemia and glycemic control in critically ill and hospitalized patients
- Pancreatic function and diabetes
- Liver Disease Diagnosis and Treatment
- Adipose Tissue and Metabolism
- Birth, Development, and Health
- Coagulation, Bradykinin, Polyphosphates, and Angioedema
- Diabetes, Cardiovascular Risks, and Lipoproteins
- COVID-19 and Mental Health
- Thyroid Cancer Diagnosis and Treatment
- Thyroid Disorders and Treatments
- Lipid metabolism and disorders
- Organ Transplantation Techniques and Outcomes
- Cardiovascular Function and Risk Factors
- Eating Disorders and Behaviors
- Fatty Acid Research and Health
- Vitamin D Research Studies
- Bariatric Surgery and Outcomes
- Apelin-related biomedical research
- Pituitary Gland Disorders and Treatments
- Parathyroid Disorders and Treatments
- Sexual function and dysfunction studies
Inonu University
2012-2024
Turgut Özal Tıp Merkezi
2022-2023
Endocrinology Research Center
2020
Fırat University
2007-2008
Non syndromic monogenic obesity is a rare cause of early onset severe in the childhood period. This form may not be distinguishable from other forms without genetic analysis, particularly if patients do exibit any physical abnormalities or developmental delay. The aim this study was to screen 41 different obesity-related genes children with non-syndromic obesity.Children (body mass index-standard deviation score >3) and (<7 years) were screened by next-generation sequencing based, targeted...
To evaluate the effects of etanercept and thalidomide in mouse model bleomycin-induced scleroderma (BLM-IS).This study involved four groups (n = 8 mice each group). Dermal sclerosis was induced by repeated subcutaneous injections BLM (10 microg) for 4 weeks BALB/c mice. Control group received only phosphate-buffered saline. The second BLM; third fourth were also given an intraperitoneal injection 100 microg or 150 mg/kg thalidomide, respectively.BLM increased serum TGF-beta1, tissue...
Prediabetes accompanied by metabolic syndrome accelerates the process leading to diabetes and causes an increase in complications. The current study aimed investigate clinical conditions accompanying prediabetes effect of association on outcomes prediabetics.
Circadian disturbances are known to affect lipid metabolism.Most of the phospholipid metabolites have been shown be under circaian control by metabolomics studies.Moreover, genes related glycerolipid synthesis were reported circadianly regulated.Data from various studies revealed a relationship between metabolism and circadian misalignments.Some proteins responsible for transfer phospholipids among plasma lipoproteins or membranes include (PLTP), lecithin cholesterol acyltransferase (LCAT),...
: The antidiabetic effect of SGLT2 inhibitors (SGLT2-is) is based on their ability to increase glucose excretion through urine by inhibiting the kidney-resident protein. Euglycemic diabetic ketoacidosis (EuDKA) an uncommon but potentially life-threatening adverse these medications, which are notable for antidiabetic, cardiovascular, and renal protective properties. This study aimed clarify impact SGLT2-is demographic, clinical, biochemical characteristics in patients with DKA.
COVID-19 is a viral disease that recognized now as pandemic by the World Health Organization. It known some infections may trigger autoimmune diseases. has been revealed also lead to pathogenesis of diseases, including Type 1 DM (T1DM) and thyroid Here, we aimed present young female patient with COVID-19, who followed up in our clinic, presented diabetic ketoacidosis (DKA), developed Hashimoto's during treatment process. In order emphasize emergence T1DM, it mask nonspecific DKA symptoms...
Thyroid disorders are associated with many cardiovascular risk factors. The importance of thyroid hormones in the pathophysiology heart failure is underlined by European guidelines Society Cardiology. However, role subclinical hyperthyroidism (SCH) left ventricular (LV) systolic dysfunction not entirely clear.This cross-sectional study included 56 SCH patients and 40 healthy volunteers. group was divided into two subgroups depending on presence fragmented QRS (fQRS). In both groups, global...
The aim of this study was to investigate the prevalence microvascular and macrovascular diabetic complications associated comorbidities in newly diagnosed pre-diabetic individuals.This cross-sectional includes 100 individuals. Fasting plasma glucose, HbA1c, oral glucose tolerance (OGTT) were tested according American Diabetes Association's diagnostic criteria for pre-diabetes, besides anthropometric measurements, lipid profiles, demographic biochemical parameters. Comorbidities like...
Metabolic syndrome (MetS) is a prevalent public health problem. Uric acid (UA) increased by MetS. We investigated whether administration of UA and 10% fructose (F) would accelerate MetS formation we also determined the effects irisin exercise. used seven groups rats. Group 1 (control); group 2 (sham); 3 (10% F); 4 (1% UA); 5 (2% 6 F + 1% 7, 2% UA). After induction (groups -7), was divided into three subgroups: 3A, no further treatment; 3B, 3C, treatment 4, UA, which 4A, 4B, 4C, Irisin 5, 5A,...
Objective: The aim of this study is to investigate whether morbidly obese female patients are suffering sexual dysfunction, in addition analyzing the effect body mass index (BMI) on functions. Method: A total 72 women admitted Endocrinology Department, whose BMI scores were 40 or over, and 28 healthy age-matched with group, under 30 included study. Considering effects functioning, control group evaluated by a psychiatric specialist. disorder according DSM-5, taking medicines that could...
Abstract Malignant thyroid lesions are the most common malignancy of endocrine glands with increasing rates in last two decades. Papillary cancer is malignancy. In our study, we aimed to quantitatively evaluate levels DNA repair proteins MSH2, MLH1, MGMT, which representative blocks patients diagnosed papillary carcinoma, chronic thyroiditis, or colloidal goiter. Total subtotal thyroidectomy material 90 nodular goiter, thyroiditis between 2009 and 2012 were retrospectively evaluated. Tissue...
Impacts of combined osteopenia
COVID-19 is the biggest pandemic of last century. While a large number cases and mortality rates direct research to clinic prognosis disease, mental health these patients has recently become matter concern. This study aims predict psychiatric morbidity possible associated markers in survivors.A total 102 survivors with infection participated this study. A questionnaire was applied participants evaluate demographic variables, history comorbid diseases, smoking, loss relative due COVID-19,...
Abstract Introduction Panhypopituitarism with acute myeloid leukemia (AML) is a very rare condition. Few cases reported in the literature have been generally associated poor prognosis. Clinical Case Here we present A 57-year-old female patient AML-M2. In first year of her follow-up, she was diagnosed central diabetes insipidus (DI)- Arginine vasopressin deficiency, when referred to endocrinology clinic complaints fatigue, polydipsia and polyuria. Hypopituitarism found following further...
Aim: Constipation is frequently seen in obese individuals. It still not fully known whether the constipation these individuals related only to excess weight or due other reasons. limited that hormones secreted from gut can play an important role constipation. In this study, we think such as intestinal peptide YY (PYY), SS, GLP-1, GLP-2 and Oxyntomodulin, which are have effects on bowel movements, may it will be tried determine how changes levels of mentioned with who problems. Materials...
Bu çalışma kapsamında diyabetik tanısı almış erişkin hastalarda sosyal destek ile umutsuzluk düzeyi arasındaki ilişki araştırılmaktadır. Tanımlayıcı araştırma olarak Türkiye’nin Güneydoğu Anadolu Bölgesi’nde yer alan bir devlet hastanesinin dahiliye klinik ve polikliniklerinde gerçekleştirilmiştir. araştırmanın evrenini, söz konusu takip edilen diyabet hastaları oluşturmaktadır. Araştırmanın örneklem sayısı, 0,05 hata, 0.95 güven aralığı evrenin temsil gücü güç analizi yapılarak 252 kişi...
Objective: Obesity is a global, chronic disease that affects both developed and developing countries. The purpose of this study to examine the effect morbid obesity affect decayed, missing, filled teeth (DMFT) index saliva values. Methods: included 50 morbidly obese, control group patients ranging in age from 18 68. DMFT was determined by clinical examination. kit used determine values [unstimulated flow rate (USFR), stimulated (SSFR), viscosity (SV), pH (SpH), buffering capacity (SBC)]....
Objectives: T wave’s peak and end interval (Tp-e), Tp-e/QT ratio Tp-e/QTc are novel markers of ventricular repolarization associated with arrhythmias. Increased arrhythmia incidence is reported in patients acromegaly. The purpose this study to evaluate using the Tp-e interval, ratio, Methods: Thirty-five acromegaly were included study. control group was consisted forty-one subjects without that having similar age, sex comorbidities. other parameters all evaluated electrocardiography....
Post-endoscopic retrograde cholangiopancreatography pancreatitis (PEP) is the most common serious adverse event in liver transplant patients The average incidence has been reported as 1.3%-15.1% prospective series. In our study, we have prospectively evaluated prevalence of nonalcoholic fatty pancreatic disease (NAFPD) after PEP via computerized tomography (CT) and determined ratio pancreas by ultrasound imaging patients.We retrospectively analyzed 2922 patient files, 146 were indicated for...
Abstract Background:The frequency of new-onset diabetes after transplant(NODAT) is 5-30% in liver transplant recipients. Aims: We aimed to analyze the and predictors NODAT patients undergoing transplantation(LTx) due acute failure(ALF), investigate whether pretransplant hypoglycemia had any effect on NODAT. Methods:Adult LTx ALF were analyzed retrospectively. The with chronic failure or excluded. measured random blood glucose(RBG) posttransplant fasting glucose(FBG). was diagnosed according...