A5075792136- Alcoholism and Thiamine Deficiency
- Liver Disease Diagnosis and Treatment
- SARS-CoV-2 and COVID-19 Research
- Adipokines, Inflammation, and Metabolic Diseases
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Coffee research and impacts
- Tryptophan and brain disorders
- Paraoxonase enzyme and polymorphisms
- Folate and B Vitamins Research
- Oral and Maxillofacial Pathology
- Apelin-related biomedical research
- Systemic Sclerosis and Related Diseases
- Autoimmune Bullous Skin Diseases
- Cynara cardunculus studies
- Nigella sativa pharmacological applications
- Drug-Induced Hepatotoxicity and Protection
- Cannabis and Cannabinoid Research
- Antioxidant Activity and Oxidative Stress
- Dermatologic Treatments and Research
- Stress Responses and Cortisol
- Medical Imaging and Pathology Studies
- COVID-19 Clinical Research Studies
- Iron Metabolism and Disorders
- Eating Disorders and Behaviors
- Lipid metabolism and disorders
Başkent University
2018
Fırat University
2007-2010
We investigated the preventive effect of lycopene on nonalcoholic steatohepatitis-induced by high-fat diet in rats. Forty male Sprague-Dawley rats were divided into 4 groups. They fed standard diet, (HFD), plus at a dose 2 mg/kg body weight and BW for period 6 weeks. Inflammation, steatosis, α-smooth muscle actin (α-SMA), cytochrome P450 2E1 (CYP 2E1) expression increased significantly HFD decreased administered lycopene. Significantly elevated levels serum alanine aminotransferase (ALT),...
In the present study, we investigated protective effect of genistein in experimental acute liver damage induced by CCl4.Forty rats were equally allocated to 5 groups. The first group was designated as control (group 1). second injected with intraperitoneal CCl4 for 3 days 2). third subcutaneous 1 mg/kg 4 starting one day before injection. fourth 7 days. fifth 8 Plasma and tissue malondialdehyde (MDA) glutathione levels, well AST ALT levels studied. A histopathological examination...
There is a large amount of convincing data demonstrating that reactive oxygen species (ROS) are involved in initiation and development many different forms neuropsychiatric disorders. The levels oxidants antioxidants schizophrenia have been evaluated. However, measurements total antioxidant response (TAR) were not evaluated up to now. Therefore, the objectives this study investigate plasma TAR subtypes. A 76 patients with 25 healthy volunteers included study. Positive Negative Syndrome Scale...
To evaluate the effects of etanercept and thalidomide in mouse model bleomycin-induced scleroderma (BLM-IS).This study involved four groups (n = 8 mice each group). Dermal sclerosis was induced by repeated subcutaneous injections BLM (10 microg) for 4 weeks BALB/c mice. Control group received only phosphate-buffered saline. The second BLM; third fourth were also given an intraperitoneal injection 100 microg or 150 mg/kg thalidomide, respectively.BLM increased serum TGF-beta1, tissue...
In Brief Purpose: An increase in plasma concentrations of homocysteine (Hcy) proliferative diabetic retinopathy (PDR) has been described. The aim this study was to investigate vitreous Hcy levels patients with PDR. Methods: Plasma and samples were obtained simultaneously at the time vitreoretinal surgery from 20 PDR 12 nondiabetic nonproliferative ocular diseases. determined by high-performance liquid chromatography. Results: mean for group 3.64 ± 0.65 μmol/L 16.04 2.75 μmol/L, respectively....
Paraoxonase 1 (PON 1) is a high-density lipoprotein (HDL)-associated enzyme with antioxidant function protecting low-density (LDL) from oxidation. PON has two amino acid polymorphisms in coding region; L/M 55 and Q/R 192. These modulate paraoxonase activity of the enzyme. decreases coronary artery disease (CAD). In present study, distribution 192 effect these on activities 1, severity CAD 277 (+) patient 92 (-) subjects were examined. genotypes determined by PCR, RFLP agarose gel...
Brown tumor is an important sign of a number metabolic bone diseases. Normocalcemic hyperparathyroidism, rare childhood pathologic finding, reveals itself with brown tumors as the only initial sign. In this study, two cases normocalcemic hyperparathyroidism accompanied by mandibular are presented.
Betatrophin is defined as a new marker in glucose homeostasis and lipid metabolism. We aimed to investigate the role of serum betatrophin full-blown polycystic ovary syndrome (PCOS) patients 47-aged healthy women, 51 PCOS were included this cross-sectional study. concentrations significantly lower group displayed positive correlation only with tryglyceride control (p < .05). A cutoff level (464.5 ng/L) was determined for according Receiver Operating Characteristic curve. Using value, 64.7%...